Background: Hepatitis is a disease of the liver caused by the infectious and non-infectious agents.
Patients &methods: A total of 600 blood donors attending blood bank at Baghdad city were included in this study , they were screened by Enzyme Immune sorbent Assay for detection of HBs Ag and anti-HCV ,that confirmed by recombinant immunoblot assay .the possible influence of the various factors on the prevalence was analyze too.
Results: Form the total donors there were 37(6.2%)and 6(1.7%)positive for HBV &HCV respectively .peak prevalence for HBs Ag was noticed in age groups (20-29)years .
Conclusion: Screening blood donors for both HBV and HCV is indispensable for safe blood transfusion. . In gen

Background: The role of cytokines in cancer immunity and carcinogenesis in general has been well established, which play an important role in pathogenesis of many solid cancer. This study aimed to shed light on the possible role of IL-6 in pathogenesis of CRC and its relationship with serum CEA level.
Patients and methods: This study covered 50subjects. It comprised of 30 patients with CRC, compared with 20 healthy normal controls. Serum IL-6 and CEA analysis were performed by ELISA.
Results: This study revealed a significant elevation in serum IL-6 level among CRC patients (16.2 pg/ml) in comparison to that of healthy control (4.8 pg/ml) (p<0.001). As well as an interesting significant increase of

Background: Homocysteine (Hcy) is a sulfur containing amino acid that is formed as an intermediary in methionine metabolism. Raised plasma homocysteine levels, which may contribute
to the increased risk of chronic liver disease.
Patients and Methods: Sixty two patients with chronic liver disease and 26 healthy individuals were included as normal controls for the study. The HPLC system was used for the determination of Hcy and vitamin B12.
Results: A highly significant Hcy concentrations were noted in all patients with cirrhosis, chronic hepatitis or liver mass. There was a trendency towards higher Hcy concentrations in more advanced stages of liver disease. The study showed that the concentrations of tot

Background: Autoimmune hepatitis (AIH) is an unresolving inflammation of the liver of unknown cause associated with interface hepatitis on histological examination,hypergammaglobulinemia and presence of circulating autoantibodies. Antibody-mediated tissue injury might be responsible for tissue injury in AIH therefore; a number of studies have been focused on the immunoglobulines in these patients .The aim of the study is to estimate the level of immunoglobulins (IgG, IgA and IgM ) in different types of Autoimmune hepatitis ( AIH).
Patients and Methods: The study was performed on 73 Iraqi patients with autoimmune hepatitis (AIH), attending the teaching hospital for gastroenterology and liver disease in a p

Background: There is a general acceptance which illustrated that auto antibodies act as a central immunological disturbance in most of the auto immune diseases, among these auto immune diseaselies the SLE
Patients and Methods: Thirty five patients with SLE were compared to twenty age and sex matched, control subjects and studied for the presence of auto antibodies, plus IL-4 and IL-6 using Elisa method and immune fluorescent method (for ANA only)
Results: Data showed that IL-6 detectable levels were statistically significant in patients with positive anti ds-DNA, but not significant statistically in ANA positive patients although it was detected in 24 (70.6%) of positive ANA patients, while there was no sta

Back ground: Visceral leishmaniasis is an endemic protozoan disease in Iraq. Recovery from this disease confers a solid and permanent immunity. Immunological assessment of our patients was carried out and the results showed a significant reduction in the percentage of CD3, CD56 and a significant increase in the percentage of CD19 in the peripheral blood lymphocyte of VL in comparison with control group.
Patients and methods: Indirect immunofluorescence technique analysis was performed to detect the percentage of CD3, CD19and CD56 positive lymphocytes.
Results: Our results in the patients groups showed decrease in the percentage of CD3, CD56 and increase in the percentage of CD19. Follow up of patients after

Background: Interleukin -6 (IL-6) as the key mediator of the acute phase reaction is of interest .elevated protein concentrations of IL-6 in the blood have been shown in patients with type 2
diabetes. This study aimed to investigate the association of IL-6 and type 2 diabetes. 
Materials and Methods: Blood samples were collected from 40 patients with type 2 diabetes and 40 person apparently healthy control were examined for IL-6 level by Enzyme Linked Immune Sorbent Assay. HbA1c determined by high pressure liquid chromatography .total cholesterol, HDL cholesterol and triglyceride were determined enzymatically. Other risk factors study like age, sex and BMI.
Results: results shows that IL-6 was highe

Background: Hydatid disease remains an important & challenging medical problem.
Case report: A62 year old male patient was admitted complaining of upper abdominal discomfort. Six days earlier he suffered from acute pain in the right upper quadrant, mild systemic allergic manifestation, a fever of 38.5oC and chills. He was managed by a new surgical approach of myoplasty of the right hemidiaphragm combined with preoperative decompression of the bile duct by an endoscopic sphincterotomy. A case search identified study describing rupture of a hydatid cyst of the hepatic dome into biliary tract. The incidence of intrabiliary rupture of hepatic hydatid cysts is 25% in patients treated with external surgical

Background: The purpose of this study was to compare the parametric measurements of transient otoacoustic (TEOAEs) in normal hearing subjects between two clinical centers in Iraq and to examine the community effect on TEOAEs characteristics.
Patients and Methods: Transient otoacoustic emission (TEOAEs) were obtained from eighty subjects (160 ears)-males and females aged (10-20 years), with Forty (40) subjects in Baghdad audiology center and forty subjects in Sulaimania audiology center (North of Iraq)[ Kurdistan-Iraq], in standard, non-linear “Fast Screen” mode. Hearing thresholds, tympanometric, and TEOAE-parameters were recorded between two clinical center groups.
Results: The cross correlation (

الخلفية: مشاكل الثدي بما في ذلك سرطان الثدي في تزايد في العراق خلال السنوات الأخيرة ، ومع ذلك ، فإن برامج الكشف المبكر والفحص باستخدام التصوير الشعاعي للثدي( بشكل رئيسي) ومساعدة الموجات فوق الصوتية كفحص تكميلي قد خفضت معدلات الوفيات بشكل كبير من هذا المرض الخبيث.

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المرضى وطرق البحث : وهي دراسة مكونة من 53 مريضة أتت للكشف عن سرطان الثدي في مستشفى الأورام التعليمي التابع لمجمع مدينة الطب في بغداد - العرا

العوامل المسببة لركود الصفراء في مرحلة الطفولة المبكرة في مستشفى حماية الأطفال التعليمي

نبذة مختصرة:

الخلفية: يتم تعريف الركود الصفراوي لحديثي الولادة على أنه ارتفاع مستمر في مستوى المصل من البيليروبين المترافق بعد الأيام الـ14 الأولى من الحياة. هناك العديد من الأسباب لحدوث الركود الصفراوي لحديثي الولادة ويجب تفريقها عن بعض لأن ال

خلفية البحث: ان المغذيات الدقيقة الأساسية الموجودة في تراكيز منخفضة جدا في الجسم مثل السيلينيوم والزنك والنحاس تلعب دورًا

مهمًا في العمليات الفيسيولوجية المختلفة وتعتبر أساسا في الأداء السليم لجهاز المناعة وقد أظهرت العديد من الدراسات أن هده المغذيات

الدقيقة قد يكون لها دور في الصرع الحراري عند الاطفال.

الهدف: تحديد مستوى الزنك والنحاس في ا

 Background :The retroperitoneal tumors is usually confined to lesions arising from tissues (muscles, fat, lymph nodes, nerves, and, developmental remnant) of this compartment but excluding origin from the retroperitoneal organs (panaceas, kidney, ureters and adrenals). The aim of the study is to focus a light on the types of retroperitoneal tumors, ways of the investigations and the presentations.
Methods :A prospective review study of 25 patients with retroperitoneal tumors has been collected in the Medical City Teaching Hospitals During the period between Jan 2001 to Mar 2004. The data included age, gender, risks factors, clinical presentations, diagnostic modalities and results of histopathology.
Results :14 males (56%) a

Back ground: Colorectal cancer is one of the leading causes of death allover the world especially in the developed countries. Each year approximately one million veterans aged 50 and older will develop colorectal cancer over the remainder of their lives and nearly 433,000 will die from it. Because most cancers are diagnosed after local or regional spread, nearly half of all patients diagnosed with colorectal cancer will die lWarly detection and management definitely decrease mortality.
Patient and methods: This is a prospective study on fifty patients with colorectal cancer admitted at the first surgical unit in Baghdad teaching hospital since March 2000 till March 2003 The data collected from those fifty patients were analyzed accor

نبذة مختصرة
خلفية: يؤدي التعرض المتزايد لعوامل الخطر لفقدان السمع إلى زيادة التعرض للصمم بين الولدان المولودين في البلدان النامية.

اهداف الداسة: تهدف هذه المقالة إلى دراسة مدى انتشار عوامل الخطر لعيب السمع عند الأطفال حديثي الولادة وتحديد تأثيرها على نتيجة اختبار السمع الصوتي الناتج عن الانبعاثات.
الطريقة: أجريت هذه الدراسة المقطعية لمدة سنة واحدة. تم

Background : The contribution of diastolic dysfunction in patients with preserved left ventricular (LV) systolic function to impaired functional status and cardiac mortality in myocardial infarction (MI) is unknown.
Materials and Methods : Assessment of LV diastolic function was performed by Doppler analysis of the mitral and pulmonary venous flow and the propagation velocity of early mitral flow by color M-mode Doppler echocardiography in 150 consecutive patients at day 5-7 following their first acute MI.
Results : Patients were classified into four groups: group A: preserved LV systolic and diastolic function (n=59); group B: LV systolic dysfunction with preserved diastolic function (n=8); group C: LV diastolic dysfunction with

Background: Alcohol remains the single most significant cause of liver disease throughout the Western world, responsible for between 40 and 80% of cases of cirrhosis in different countries. Many of the factors underlying the development of alcoholic liver injury remain unknown, and significant questions remain about the value of even very basic therapeutic strategies.
Patients and Methods: In a cross sectional study, 113 alcoholic patients with evidence of liver disease in the absence of other significant etiology attending the Gastoenterorology and Hepatology Teaching Hospital between December 2001 and December 2003 were studied for the hematological and biochemical spectrum of alcoholic liver disease in

Background: Clinical classification of patients with acute coronary syndrome is essential step in identifying severe cases before referring them, fairly quickly, for the ultimate investigation of coronary angiography .Hence it is important to find out the extent at which the severity of the disease, based on clinical classification, agrees with its severity at angiography and to see whether traditional Risk factors or pas ischaemia played a role.
Patients and Methods : The angiographer data of 178 consecutive pts with Acute Coronary Syndrome (ACS) were retrospectively analyzed. The pts consisted of 114 with Unstable Angina (UA)  and 64 pts with Non-ST-Segment Elevation Myocardial Infarction (NSTEMI). Pati

Background The Medicines and Health care products Regulatory Agency stated in 2003 that doctors should endeavor to avoid using products in treatments not covered by their product license. Foley catheters are commonly used in the management of epistaxis although their product license does not cover this.
Aims : To study the extent of the use of these catheters and the knowledge that otolaryngologists had of their legal status.
Method : By undertaking a questionnaire survey of some Otolaryngologists in Baghdad 
Results : Most members appear to use Foley catheters in the management of epistaxis; however most of them are not aware that the product is not licensed for this purpose. Because of this lack o

Background: - Diabetic foot infections may be classified as superficial or deep. Bacteria are liable to enter any cut or ulcer causing infection. Defect in treatment of infected deep diabetic foot may result in oesteomyelitis, limb loss, and even death.
Methods: - Microorganisms were isolated and identified from both superficial & deep foot ulcers infection of (60) diabetic patients.
Results: - The present results showed that high incidence (30.8%) of Escherichia coli (E-coli) was isolated from dry - superficial foot ulcers followed respectively by Staphylococcus epidermidis (S. epidermidis). 3.1 % and 15.4% of Proteus mirabilis (P. mirabilis), equal Percentages for Klebsiellae Pneumoniae (K. pneum

Seventy- four cases of clinically diagnosed Rheumatoid Arthritis (RA), fifty cases of systemic lupus erythematosus (SLE), and thirty healthy normal controls were investigated for detection of rheumatoid factor (RF), total serum immunoglobulins (Igs), antinuclear antibody (ANA), and ANA subtype anti-double stranded DNA (anti-ds DNA).
Patients with RA showed 58.1% positive for RF comparable with 14% positivity in SLE patients and 6.6% in normal individuals. Serum Igs (IgA,IgG) were found to be elevated in RA and SLE
patients (62.2% , 36.5%) (54% , 38%) respectively. This study revealed that ANA is found in 88% of SLE patients sera and 78% of these ANA is ds DNA in comparison with only 6.8% of RA sera wer

Background: to evaluate subcutaneous pancreatic transplantation in an experimentally induced diabetes mellitus in golden hamsters.
Methods - many indexes (histological /using two stains, histochemical /using three enzymes, morphometrical and biochemical /blood glucose level) were employed in this assessment. Alloxan was used as ß-cytotoxic therapy (to induce diabetes mellitus), and cyclophosphamide was employed as immunosuppressive agent.
Results - high rate of success of transplantation (clearly evident by microscopical features of viable endocrine and exocrine tissue of transplanted pancreas and great tissue vascularization, normal enzymatic activities and significant lowering of blood glucose level

Background: During the past several years, there has been a rapidly escalating clinical need to perform IHC stains that require quantitative interpretation. Automated Cellular
Imaging System is used to analyze immunohistochemically stained slides, primarily for cancer-related diagnostics. Studies have shown that the device offers accuracy,
precision, and reproducibility of immunostained slide analysis exceeding that possible with manual evaluation, which was the prevailing method.
Aim of the study In this article we will demonstrate that meaningful image analysis of immunohistochemical staining studies can be performed using inexpensive, widely distributed
graphics software (Adobe Photoshop) on a personal

Background: The Aim Of This Study Is To Determine The Modalities Of Treatment Of GTD In Baghdad Teaching Hospital And To Assess The Efficacy Of Our Management Protocols.
Patients &Methods: Department Of Obstetrics & Gynecology- Baghdad Teaching Hospital. Retrospective Analysis Of Case Records Between January 1999 To December2000. 41 Patients' Data Were Reviewed For Age, Gravidity, Parity, Blood Group, Antecedent Pregnancy And Clinical Presentation At The Time Of Diagnosis. Monitoring Of Hcg Level Before And After Chemotherapy, Other Investigations Were Reviewed, Looking For Number, Size And Site Of Metastasis. The Patient Were Classified According To WHO Scoring System. We Evaluate The Lines )f Ma

Background : A retrospective study was done in the Pediatric ward /AL-Kadhimiyia Teaching Hospital on cases diagnosed as idiopathic thrombocytopenic Purpura admitted since the first of January1992 – the end of December 2004.
Aim of the study : The objective of this paper is to review the natural history of idiopathic thrombocytopenic Purpura , presenting feature and response to treatment.
Patients and methods : The review included age ,sex , clinical presentation , physical finding , complications , investigation ,treatment and course of the diseases .
Results: total number of the patients were 65, peak age was between (2 -5) years, 40 cases (61.53%). Females were affected more than Males with male: female

Background: Diabetes mellitus type-1 is the most common endocrine metabolic disorder in childhood. Mononeuropathy, generalized polyneuro-pathy and autonomic neuropathy are frequent complications of diabetes mellitus and may give rise to troublesome manifestations.
Methods: sixty children suffering from type 1 diabetes mellitus admitted in Children Welfare Hospital- Medical City-Baghdad in the period from 1st Dec2000-31stJuly 2001 were included in
this prospective descriptive study. History, especially symptoms of peripheral neuropathy, examination specially signs of peripheral neuropathy, absent sinus arrhythmia and postural
hypotension and investigations like nerve conduction study were all performed and ana