Background: Unilateral sinonasal disease is commonly encountered during the practice of the otolaryngologists, the etiology include a wide variety of diseases ranging from simple
acute inflammation to highly malignant diseases. The clinical, computed tomography and histopathology differs between inflammatory and neoplastic diseases.
Patients and Methods: A prospective study carried out at the Otolaryngology department, Baghdad Medical City, Hospital of specialized surgeries between Jan.2007 to Nov.2008.The study involved 114 patients with symptoms and signs of unilateral sinonasal disease, a careful history, complete clinical examination and radiological investigations were done to all patients as well

Background: Promotion of bone health is particularly important for young women at reproductive age group, as the critical years for building bone mass are from pre-adolescence to about age 30 years.
patients and Methods: This cross sectional study was performed on three groups, first group of 30 women who had used combined pills for more than 2 years, second group of 30 women who had used Depo-Provera for more than 2 years, last group contain 30 women who had used barrier method or they didn’t use any contraceptive as a control group.Bone mineral density (BMD) of lumbar spine (L2-L4), right proximal femur was determined by dual energy x-ray absorptiometry in (femoral neck, greater trochanter, ward’s t

Background: To compare the diagnostic value of hysteroscopy with conventional curettage and to evaluate the sensitivity of both methods to detect intrauterine endometrial pathology in patients with abnormal uterine bleeding.
patients and Methods: This prospective study carried on 100 patients underwent diagnostic hysteroscopy as well as dilatation and curettage for abnormal uterine bleeding in two teaching
hospitals, Al Yarmouk and Al Kadhmiya Teaching hospital / Baghdad from the period of Jan. 2002 to Dec. 2003, endometrial specimens were sent for separate histological study, the sensitivity of both methods were assessed according to the operative and histological findings.
Results: High sensitivity and

Background: cholecystectomy is one of the most frequently performed operations. Open cholecystectomy has been the gold standard for over 100 years .laparoscopic cholecystectomy was
introduced in 1980s.
Patient and methods: Two hundred patients admitted to first surgical unit in Baghdad teaching hospital from first May 2007- first May 2009 with gall stone disease both symptomatic and
asymptomatic, of both genders and any age were evaluated by history, examination and investigations and data was collected.
Results: Two hundred patients underwent LC in the study period. 181(90.5%)were females and 19(9.5%)were males. The most common age group was between 21-40 years (55%), bleeding was the commonest compl

Background: Common complications of subcutaneous insulin injection include lipoatrophy and lipohypertrophy which may lead to erratic absorption of the insulin with the potential for poor glycemic control and unpredictable hypoglycemia. Other cutaneous complications are local and systemic insulin allergy.
Patients and methods: The study included 150 patients with type1 diabetes mellitus attending thediabetic clinic of Children Welfare Teaching Hospital who were assessed for cutaneous
omplications of insulin therapy especially at the sites of the injections. Data collected evaluated using chi square and Pvalue.
Results: Out of 150 patients, the male to female ratio was 1:1.3, with mean age of 11.34 years

Background: Hypotonia is not a specific medical disorder, but a potential manifestation of many different diseases and disorders. The long-term effects of hypotonia on a child's development and later life depend primarily on the severity of the muscle weakness and the nature of the cause.
Patients &Methods: A prospective, cross sectional descriptive study in which 62 patients with hypotonia, age 3months to13 years, were evaluated in children welfare teaching hospital /Baghdad (a tertiary care center), over 4months Period (1st of January to 1st of May,2008 ) . Children were categorized into groups of central , peripheral& systemic hypotonia, and specific diagnosis of each of groups was made by clin

Background: Study the correlation between the left ventricular end diastolic volume (LVEDV), ejection fraction (EF) and the development of arrhythmia.
Patients and methods: Two hundreds patients with documented acute coronary syndrome and myocardial infection with dysrhythmia documented by ECG and holter monitoring assessed at the cardiac department at Baghdad teaching hospital over the period Jan-Dec 2007. These dysrhythmias were corelated with left ventricular end diastolic volume and ejection fraction.
Results: The patients were divided into 4 groups according to LVEDD and EF. The 1st group, 40 patients (20%) found to have non sustained ventricular tachycardia was associated with higher LVEDD (62-72

Background: Hydatid disease also known as echinococcosis or hydatidosis , is caused by infection with larva (metacestoide) of tape worms of the genus Echinococcus.
Materials and methods: Twelve Rabbits were immunized with three types of antigens (Hydatid cyst fluid antigen; Protoscoleces antigen and Germinal and Laminated layer antigen) according to a specific immunization program and we used indirect hemagglutination test( IHAT) and Enzyme Linked Immuno Sorbent Assay(ELISA) for detecting the anti-Echinococcus antigens in the serum of these animals.
Results: The highest titter of antibodies were recorded in the Rabbit serum when use the first antigen (Hydatid cyst fluid) by using IHA method (1:64)after

Background: several new inflammatory markers have emerged as strong predictors of cardiovascular disease in healthy and non-healthy subjects, one of these markers is hs-CRP, which has been proposed as independent risk factor for cardiovascular disease, and it is positively associated with body weight. Little is known, however, about the utility of hs-CRP and other biomarkers in obese hypertensive Iraqi post menopausal women.The aim of study is to examine the hypothesis that there is a relation between obesity, hypertension and a chronic low-grade inflammatory status (represented by high hs-CRP).
Patients and Methods: A total number of 99 postmenopausal women classified into obese hypertensive group (

Background: The hippocampus is empirically assumed to have different functions, of which the best known are: the representation of self-location in cognitive dimensions, and the storage and retrieval of memory.
Materials and methods: Eleven adult male albino rats were used. Brain specimens were processed into paraffin blocks, sectioned (10 μm thick), and stained using Haematoxylin and Eosin, and Luxol Fast Blue MBS counterstained with Cresyl Violet. Morphometric analysis was done through eyepiece micrometers.
Results: The lamellae of the hippocampus were morphometrically evaluated in context of embryogenesis and nerve fiber content.
Conclusion: This study confirmed the existence of differences in nerve

Background: Cerebral ventricular enlargement has been associated with many neurological disorders. Whether this enlargement is primary or secondary to these pathological conditions remains controversial. To define such enlargement, one must have measurements in normal subjects (controls).
Patients and methods: One hundred-twelve (66 male and 46 females) apparently healthy normal subjects, with age ranging between 10-69 years were subjected to C. T scans as part of routine diagnostic workup for complaint of headache or recent minor motor-vehichle accident The ratio (measured as percent) of the ventricular-cross area of the lateral ventricle The maximum width (MTW) of the third ventricle was also deter

Background: Nodal osteoarthritis is one of the most common arthropathy worldwide, the etiology is uncertain but many biochemical markers are recognized. Many studies have shown that leptin might have a role in the pathogenesis of osteoarthritis, but little is known about the relation between serum leptin and nodal osteoarthritis.
Subjects and method: 52 women with nodal osteoarthritis and 40 apparently healthy women as a control were included in the study; serum leptin was measured in all subjects. Student t-test was applied to find out the significance of difference in the mean v
Results: There was a significant difference in the mean of serum leptin between patients and control groups.
Conclusion:

Background: Oral squamous cell carcinoma continues to be a major health problem in Iraq as well as in other countries. Many attempts were made to study molecular markers in oral squamous cell carcinoma and to link them to tumor grade, stage and prognosis, besides studying their role in carcinogenesis. The present study has been designed to detect mRNA of c-myc in oral squamous cell carcinoma compared to oral dysplasia and to link the marker to grade and degree of the two pathologies.
Materials and methods: Forty two cases, including 30 cases of oral squamous cell carcinoma and 12 cases of oral dysplasia were included in this study. Sections on positively charged slides were made from their paraffin blocks

Background: Faith healing is common in Arab culture. Obsessive-compulsive disorder is linked to religious beliefs and this can affect its management as patients may seek help from faith healers rather than mental health professionals.
Patients and methods: Patients who received a diagnosis of OCD according to DSM-IV-TR completed a questionnaire containing questions about age, gender, marital state, residence, income, level of education, and occupation. Also, data was collected on help-seeking from a faith healer and on religiosity. The data was analyzed by using the statistical package of the social sciences (SPSS).
Results: 58.5% of OCD patients had sought help from faith healers and this was significantly

Background: Emergency ambulance personnel (EAP) are vulnerable to PTSD. In Iraq, EAPs were exposed to life threatening situation during political violence conflict post 2003 Gulf war. This study was carried out to report on PTSD among EAP.
Patients and Methods: A total of 189 male EAPs were selected randomly from the Dept. of ambulance in Baghdad. A questionnaire form was filled for each EAP. The form included the
symptoms of PTSD according to DSM- IV (intrusive, avoidance and hyperarousal symptoms). Demographic data and exposure to violence accident, type of accident and duration of damage were included, also.
Results: The mean age of EAP was 38.5 ± 9.4 years. There was 122 (64.5%) had PTSD. Age, 

This article aims to cast a shadow over the history of mental health education and training in Iraq and a projection of Islamic scientific heritage in Baghdad during the seventh century. It also discloses the foundation of first teaching and training centers in psychiatry focusing on the marked contribution of the pioneer psychiatrists. Introduction. Up to our knowledge there is no elaborate published literature focusing on historical role of Iraq in mental health education and training and its current reality apart from scares data about mental health in Mediterranean region as a whole. In this article, we try calling the attention to the outstanding contribution of Iraq in mental health and medical educati

Background: depressed mood and anxiety are common symptoms in hospitalized cancer patients .it is often presumed that anxiety and depression affect the occurrence and experience of physical symptoms . the researcher was aimed to assess the level of depression among cancer patients and the chemotherapy side effects and to find out the significant difference between depression level regarding these side effects.
Patients and methods: A descriptive analytical study was conducted on a purposive sample of 50 cancer patients from both sexes who were admitted to Radiation and Neuclur Medicine Hospital in Baghdad for the purpose of giving chemotherapy for the period from April 4th to June 20th , 2008. A structure

Background: To study prevalence and method of diagnosis of acute rubella Infection during early pregnancy in Iraq.
Patients and Methods: Clinical signs and symptoms of acute rubella infection were looked for in (170) pregnant women looked before (12) weeks of gestation .Serial rubella specific IgG and IgM serological testing was done in these (170) women before (12) weeks of pregnancy, after (3) weeks, and again at (18-20) weeks of gestation.
Results: Three woman had clinical signs and symptoms of rubella infection from (26) woman were IgM positive at (9) weeks of pregnancy; (94) were IgG +ve but IgM –ve initially and also on repeat sampling after (3) weeks; while (50) women were nonimmune (IgG and I

Background: Disinfection of denture and soft denture liners became among the priorities for cross contamination control as well as patient's health. All the trials aimed to have maximum infection control with minimal adverse changes in the materials properties.
Materials and methods: Discs of 30x2mm were made from Coe Super Soft and Coe Soft denture liners. Every 5 specimens were immersed separately and daily in CHX, Sodium hypochlorite and chlorine dioxide, control group specimens were immersed in the distilled water. Hardness property of the experimental and control groups was evaluated by using Shore A durometer after 1, 7, 30 days. 
Results: Statistical analysis indicated non significant difference

Background: Benign prostatic hyperplasia and prostatic adenocarcinoma are two of the most common pathologic mass lesions. Both are encountered mainly in elderly males. The caspases family is a group of at least 15 known proteases that serve as initiator & effector molecules of the apoptosis pathway. Caspase-3, in particular, is thought to play a pathogenetic role in both prostatic hyperplasia and carcinoma. Finasteride is a medication that has routinely been given to patients with hyperplasia and carcinoma; its prostate size-reducing effect is thought to be mediated through caspases.
Patients and methods: fifty patients with prostatic mass lesions were included in this study (20 with hyperplasia &

Background : AgNOR parameters are well known to pathologists as a proliferation marker with advantage over other proliferation markers of being cheaper, simpler and able to assess
proliferation speed as well as state , AgNOR stainability was found to be well preserved in smears kept for up to 2 years , studies have shown that AgNOR values can serve as a useful
prognostic parameter and a marker for tumour progression in different carcinomas (1) This study was conducted to see the importance of AgNOR staining in the peritoneal fluid
cytopathological examination
Patient and Methods: It was a descriptive and prospective study conducted in Department of cytopathology in the medical city and Department of pathol

Background: Many workers have described the prevalence of HBV markers and anti-HCV among selected populations including health care personnel in Iraq. The purpose of this study is to describe the demographic characteristics and risk factors of hepatitis B and C in a sample of Iraqi health care workers (HCWs).
Materials and methods: A total of 1656 HCWs selected from Baghdad city was included in this study. A questionnaire form was filled for each HCW by direct interview. The data requested
included demographic characteristics and risk factors of exposure to HBV and HCV. HCWs were screened for the presence of HBsAg, anti-HBs and anti-HCV.
Results: A higher prevalence of HBsAg, anti-HBs and anti-HCV was de

Background: Human leukocyte antigen (HLA) is the most polymorphic genetic system in man. The genes of this region influence susceptibility to certain diseases.
Patients and methods: Immunofixation test is the method used to asses C4 polymorphism of 100 blood samples of 60 AIH patients and 40 healthy normal controls.
Results: An increased frequency of C4A*Q0 was observed for patients group versus control group with P-value (0.003).
Conclusions: This finding demonstrated that C4A*Q0 might play a role in AIH susceptibility.

Background: The role of cytokines in cancer immunity and carcinogenesis in general has been well established, which play an important role in the pathogenesis of many solid cancers.This study aimed to estimate serum levels of IL-2 and IL-4, and to shed light on the correlation of these interleukins with progression of breast cancer.
Patients and Methods: The study included 80 women, it comprised of 45 breast cancer patients, 12 patients with benign breast lesions and 23 apparently healthy controls. ELISA method has been used for estimation the level of IL-2 and IL-4 in serum of three studied groups.
Results: This study showed elevation of IL-4 level in the sera of breast cancer patients with significant dif

Background: Cytokines have long been implicated in the pathogenesis of autoimmune diabetes in a number of studies, and playing a role in the initiation of β-cell damaging process. The objective of this study is to gain more understanding about the role of cytokines in initiation of T1DM, through assessment of IFN-γ, IL-10 and IL-6 in diabetic patients.
Patients and methods: A total of 60 patients who were newly diagnosed as having T1DM (diagnosed less than five months) were included in the present study. Fifty apparently healthy control subjects were underwent the measurement of serum IFN-γ, IL-10 and IL-6 by ELISA.
Results: Higher serum levels of IFN-γ, IL-10, and Il-6 were observed in the investigated

Background: To study prevalence and method of diagnosis of acute rubella Infection during early pregnancy in Iraq.
Patients and Methods: Clinical signs and symptoms of acute rubella infection were looked for in (170) pregnant women looked before (12) weeks of gestation .Serial rubella specific IgG and IgM serological testing was done in these (170) women before (12) weeks of pregnancy, after (3) weeks, and again at (18-20) weeks of gestation.
Results: Three woman had clinical signs and symptoms of rubella infection from (26) woman were IgM positive at (9) weeks of pregnancy; (94) were IgG +ve but IgM –ve initially and also on repeat sampling after (3) weeks; while (50) women were nonimmune (IgG and I

Back ground: A urinary tract infection is one of the most common diseases occurring from neonate up to geriatric age groups
Patients and Methods: A total of (100) Midstream urine (MSU) samples were collected from patients having signs and symptoms of Lower urinary tract infection. These patients were attending Urology Clinic, Ramadi General Hospital.
Result: Culturing of (100) MSU samples on MacConky and blood agar resulted in (5) types of bacteria which included: Escherichia coli (46%) and it was found the most frequent bacteria causing LUTI. This is followed by Klebsiella pneumonia (23%), Pseudomonas aeruginosa (13%), Proteus mirabilis (10%) and Staphylococcus epidermidis (8%).
Conclusion: Out of

Back ground: A urinary tract infection is one of the most common diseases occurring from neonate up to geriatric age groups
Patients and Methods: A total of (100) Midstream urine (MSU) samples were collected from patients having signs and symptoms of Lower urinary tract infection. These patients were attending Urology Clinic, Ramadi General Hospital.
Result: Culturing of (100) MSU samples on MacConky and blood agar resulted in (5) types of bacteria which included: Escherichia coli (46%) and it was found the most frequent bacteria causing LUTI. This is followed by Klebsiella pneumonia (23%), Pseudomonas aeruginosa (13%), Proteus mirabilis (10%) and Staphylococcus epidermidis (8%).
Conclusion: Out of

Background: Molecular DNA hybridization has confirmed more than 120 different human papilloma virus (HPV) genotypes. A small group of them have high- risk oncogenic potential. Many studies have described an association of such high risk-HPV genotypes with a variety of oral lesions including squamous cell carcinoma, leukoplakia, and lichen planus. 
Materials and Methods: A total number of 42 tissue specimens, representing 27 patients with oral lichen planus and 15 apparently-healthy oral tissues, were included in this study. The molecular methods for HPV detection and genotyping were performed by in situ hybridization(ISH) using cocktailed- and specific high- risk HPV DNA probes, respectively.
Resu

Background: The critically ill patient is at risk of developing intensive care acquired infection, with the lungs being especially vulnerable. Ventilator associated pneumonia (VAP) occurring after two days of mechanical ventilation and it is the most nosocomial infection seen in the intensive care unit .The establishment of an accurate diagnosis of ventilator associated pneumonia remains problematic and yet there is still no accepted "gold standard" for the diagnosis.
Patients& Methods: This is a cross section study for 328 patients admitted to intensive care unit at medical city teaching hospital. Full history, physical examination and investigation were done after 48 hours of admission according to