The main goal of this paper is to introduce and studya new concept named Ᵹ*-supplemented which can be considered as a generalization of W-supplemented modules and Ᵹ-hollow module. Also, we introduce a Ᵹ*-supplement submodule.Many relationshipsof Ᵹ*-supplemented modules are studied. Especially, we give characterizations of Ᵹ*-supplemented modules and relationship between this kind of modules and other kind modules for example every Ᵹ-hollow (Ᵹ-local) module is Ᵹ*-supplemented and by an example we show that the converse is not true.

       In this paper normal self-injective hyperrings are introduced and studied. Some new relations between this concept and essential hyperideal, dense hyperideal, and divisible hyperring are studied. 

The main goal of this paper is introducing and studying a new concept, which is named H-essential submodules, and we use it to construct another concept called Homessential modules. Several fundamental properties of these concepts are investigated, and other characterizations for each one of them is given. Moreover, many relationships of Homessential modules with other related concepts are studied such as Quasi-Dedekind, Uniform, Prime and Extending modules.

This article introduces a novel procedure to detect an approximate solution to Fredholm fractional integro-differential equations with linear type (LFFIDE) defined using Caputo fractional derivative. The new procedure approximates the solution using three types of polynomials: Laguerre polynomials, Hermite polynomials, and Legendre polynomials, thereafter transforming the problem into a linear programming problem. The approximate solutions are compared using testing examples to examine the efficiency of the suggested approach. Also, a comparison with the other methods using the same polynomials illustrates The effectiveness and consistency of the proposed technique. Finally, the error analysis of the proposed technique and convergent are di

The relationship between government revenues and the fiscal balance represents a central pillar in the analysis of fiscal sustainability. However, its modeling faces a fundamental challenge in the form of structural uncertainty, which is not captured by point estimates in traditional models such as ARDL, as these models assume structural stability that is inconsistent with the nature of rentier economies. The current study aims to develop a fuzzy framework by constructing a Fuzzy Autoregressive Distributed Lag (FARDL) model. This is achieved through integrating the Autoregressive Distributed Lag (ARDL) approach with fuzzy logic theory, thereby enabling the incorporation of uncertainty into the inherent structure of the economic rela

يتناول هذا البحث لهجات شبه الجزيرة العربية وهي مجموعة من اللهجات التي تنتمي إلى اسرة لغوية واحدة وقد عمدنا إلى هذا المصطلح الذي اطلقته الدكتورة ولاء صادق الأسدي نسبة إلى الموقع الذي انطلقت منه القبائل الناطقة بتلك اللهجات وهو شبه الجزيرة العربية ,وقد تم اطلاق لفظة اللهجات بدلا من (اللغات) على اعتبار ان تلك اللهجات منبثقة من لغة جامعة واحدة وهي ما يطلق عليها اللغة الأم لتلك اللهجات وإن ذكرنا في هذا البحث الاخت

Introduction:Visceral leishmaniasis (VL), also known as kala-azar, is a diffuse protozoan infection caused by Leishmania donovani complex. VL is principally caused by L. donovani and L. infantum (synonym L. chagasi in South America). The parasite targets the reticulo-endothelial system, with penetration of the spleen, liver, bone marrow and lymph nodes lead to organomegaly and pancytopenia. Organic pentavalent antimonials have been the first-line drugs for the therapy of leishmaniasis for the latest six decades, and clinical resistance to these drugs has emerged as a primary obstacle to successful treatment and control. Miltefosine has been shown to be higher or equivalent to presently approved essential medicines for at least one of viscer

Aim: The aim of this study was to investigate the effect of LPS in immune response through detecting some immune markers by IHC technique in the liver of mice infected with Leishmania donovani (VL). Methods: Three groups of eighteen mice were created: the first was control negative (non-infected), the second was control positive (infected with 2X107 promastigotes of Leishmania donovani), and the third group was infected with 2X107 promastigotes of Leishmania donovani and treated with 40 ng/ml of LPS. The treatment was given orally twice daily for one month. Mice were dissected, and the liver separated for an immunohistochemistry study for the markers (BCL-2, Caspase-3, CD3, CTLA-4). Results: The results showed there was significant elevatio

في هذه الدراسة تم أستخدام ثلاثة مستخلصات نباتية تعود للنباتات التالية : نبات الزعتر البري Thymus vulgaris, دباغ الرمان Punica grantum ولحاء البلوط (الجفت) Quercus robur.  اظهرت النتائج تأثير كبير للمستخلص المائي والكحولي للجفت على اكياس الطفيلي مقارنة بالنباتين الاخرين, يليه في ذلك المستخلص المائي والكحولي لدباغ الرمان ثم في النهاية يأتي المستخلص المائي والكحولي للزعتر البري

Leishmaniasis a vector- borne disease caused by obligate intra -macrophage protozoa, is characterized by diversity and complexity. Leishmania are one of different genera within the family Trypanosomatidae. Visceral leishmaniasis occurs universally, but >90% of the cases are in five countries: north-eastern India, Bangladesh, and Nepal in the Indian subcontinent, Sudan in Africa and north-eastern Brazil in South America. Sodium stibogluconate (Sb) has become ineffective in the 1990’s in most of the high -burden areas and must be replaced. However, none of the traditional alternatives was satisfactory. Oral drugs are very suitable as the need for hospitalization and related costs are eliminate

Hydatiosis is a widespread chronic zoonotic parasitic disease caused by helminthic larval stage of tapeworm Echinococcus granulosus.. In last year's many methods are used to activate and modulate the response of immune system of the host in order to evade the invasion of the parasite. The present investigation was aimed to find out the effect of attenuated protoscolices on the viability of lymphocytes which play very important role in the immune response against many parasites and the reflect of this attenuation on hydatid cyst protoscolices infectivity in vivo. Four groups of white male BALB/c mice were experimentally infected with helium-neon laser attenuated protoscolices that exposed to helium –neon laser for (10,30,50,100) minutes re

Visceral leishmaniasis (VL) is a parasitic disease that affects public health. It is described by weight reduction, irregular fever bouts, anemia, and amplification of the spleen and liver.

The combined effects of glycemic dysregulation, dyslipidemia, and cellular stress responses lead to increased expression of glucose-regulated protein-78 (GRP-78), a key mediator in type 2 diabetes mellitus (T2DM) development. Due to its involvement in glucose and lipid metabolism, GRP-78 is considered a potential therapeutic biomarker. This study aimed to assess the impact of various antidiabetic medications on GRP-78 levels in individuals with T2DM. A cross-sectional study comprised 134 participants: 96 T2DM patients who were divided into patients under treatment with glucovance 500 (n=38), or insulin injection (n=42), and newly diagnosed diabetic patients (n=16). A control group of 38 healthy subjects were enrolled. Serum levels G

     Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age, characterized by anovulatory, infertility and metabolic disturbances. This study aimed to assess the diagnostic accuracy of Leucine-rich alpha-2-glycoprotein-1 (LRG1) and xanthine oxidase (XO) activity as novel biomarkers for PCOS, as well as to explore the relationship between LRG1 and XO activity across different groups. A total of 150 married women, aged 18-46 years were enrolled and divided into three groups: 50 with PCOS under treatment, 50 PCOS without treatment conditions shared by women with polycystic ovary conditions, and 50 healthy women. Serum samples were analysed to measure LRG1, xanthine oxidase (XO) activity,