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Teratogenic Effect of Keppra (Levetiracetam) Drug on the Kidney in Albino Rat (Rattus rattus)

Levetiracetam (LEV) is new antiepileptic drugs (AEDs), usually used with other drugs in case of inadequate control of seizures. It is usually discharge with the breast milk. This study was conducted for the evaluation of the effect of levetiracetam on the kidney after 3 and 7 day newborn albino rats (Rattus rattus). A total of 20 rats were taken which were divided into two groups (A/control and B/ treated). The rat pregnant group (A) represents control group which has given distilled water orally during the pregnancy period and continued in taking of till one week newborn and (B) represents treated groups the drug was administered (350 mg/kg/day) orally during the pregnancy period and continued in taking of drug till one week newborn. The statistical analysis of the result revealed that the mean values of the glomeruli diameter at 3 and 7 days newborn of the treated groups showed significant increase (p<0.05), and the mean values of the renal tubules diameter at 3 days newborn of the treated groups showed no significant increase (p≥0.05), but at 7 day newborn of the treated group showed significant increase (p<0.05). Histological study of the kidneys in treated group at 3, 7 days newborn, showed histopathological effect of kidney tissue represented by cortex damage where glomerulus emerged (degeneration , loss there nucleus, glomerular dead cell , small in size, glomerular cells accumulation and enlargement space was present between the glomerulus and glomerulus space , shrinking and atrophy of glomerulus). As well as, the damage was evident in the medulla where tubules emerged (swelling epithelial cells of collecting tubules , enlargement in size together narrow space between the proximal convoluted tubule, degeneration of collecting tubules , loss there nucleus and detached cells of collecting tubule from basement membrane). This study disclosed that LEV can induce already not reported severe malformation if it is used constantly through the implantation, an organogenesis stages of pregnancy. Therefore, it is proposed that great caution should be practiced in using LEV during the early stages of pregnancy until further studies are performed to better understand these effects.

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Publication Date
Sat Mar 06 2010
Journal Name
J. Of University Of Anbar For Pure Science
Some Results on Epiform Modules

The concept of epiform modules is a dual of the notion of monoform modules. In this work we give some properties of this class of modules. Also, we give conditions under which every hollow (copolyform) module is epiform.

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Publication Date
Thu Nov 17 2022
Journal Name
Journal Of Discrete Mathematical Sciences And Cryptography
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Publication Date
Mon Jan 30 2023
Journal Name
Iraqi Journal Of Science
More on Result Involution Graphs

     The result involution graph of a finite group , denoted by  is an undirected simple graph whose vertex set is the whole group  and two distinct vertices are adjacent if their product is an involution element. In this paper, result involution graphs for all Mathieu groups and connectivity in the graph are studied. The diameter, radius and girth of this graph are also studied. Furthermore, several other graph properties are obtained.

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Publication Date
Tue May 30 2023
Journal Name
Iraqi Journal Of Science
Some Cases on Cozy Partitions

     The cozy partitions achieved more creativity by emerging with many topics in representation theory and mathematical relations. We find the precise number of cozy tableaux in the case  with any number of  and . Specifically, we use the MATLAB programme that coincided with the mathematical solution in giving precision to these numbers in this case.

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Publication Date
Mon Oct 17 2022
Journal Name
Journal Of The Faculty Of Medicine Baghdad
A Review on Viral Encephalitis-

Background: Inflammation of the brain parenchyma brought on by a virus is known as viral encephalitis. It coexists frequently with viral meningitis and is the most prevalent kind of encephalitis.

Objectives: To throw light on viral encephalitis, its types, epidemiology, symptoms and complications.

Results: Although it can affect people of all ages, viral infections are the most prevalent cause of viral encephalitis, which is typically seen in young children and old people. Arboviruses, rhabdoviruses, enteroviruses, herpesviruses, retroviruses, orthomyxoviruses, orthopneumoviruses, and coronaviruses are just a few of the viruses that have been known to cause encephalitis.

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Publication Date
Mon Jan 30 2023
Journal Name
Iraqi Journal Of Science
On Graph- Syriac Letters Partition

     The Syriac language is one of the ancient Semitic languages that appeared in the first century AD. It is currently used in a number of cities in Iraq, Turkey, and others. In this research paper, we tried to apply the work of  Ali and Mahmood 2020  on the letters and words in the Syriac language to find a new encoding for them and increase the possibility of reading the message by other people.

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Publication Date
Wed Aug 11 2021
Journal Name
International Journal Of Interactive Mobile Technologies (ijim)
Survey on 3D Content Encryption

<p class="0abstract">The rapidly growing 3D content exchange over the internet makes securing 3D content became a very important issue. The solution for this issue is to encrypting data of 3D content, which included two main parts texture map and 3D models. The standard encryption methods such as AES and DES are not a suitable solution for 3D applications due to the structure of 3D content, which must maintain dimensionality and spatial stability. So, these problems are overcome by using chaotic maps in cryptography, which provide confusion and diffusion by providing uncorrelated numbers and randomness. Various works have been applied in the field of 3D content-encryption based on the chaotic system. This survey will attempt t

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Publication Date
Mon Mar 01 2021
Journal Name
Journal Of Physics: Conference Series
On Quasi-Small Prime Modules
Abstract<p>Let R be a commutative ring with identity, and W be a unital (left) R-module. In this paper we introduce and study the concept of a quasi-small prime modules as generalization of small prime modules.</p>
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Publication Date
Thu Apr 27 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
On Semi-p-Proper Mappings

  The aim of this paper is to introduce a new type of proper mappings called semi-p-proper mapping by using semi-p-open sets, which is weaker than the proper mapping. Some properties and characterizations of this type of mappings are given.

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Publication Date
Fri Sep 02 2022
Journal Name
مجلة العلوم القانونية
Supervision Controls on Companies Concentration

The main objective of controlling companies Concentration is to prevent their potential anti-competitive effects on the competitive structure of the relevant market, in order to protect freedom of competition in it. In this context, it is necessary to verify that these operations do not impede effective competition or reduce it significantly by making it less than it was before, it is necessary to Anticipate all the effects In order to achieve the goal of controlling on it and revealing their potential restrictive effects. So there must be Auditing Norms that enable the authorities entrusted with the protection of competition and the prevention of monopolistic practices to evaluate these effects and determine their positive and negative as

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