Breast cancer is the most prevalent malignancy among women worldwide, in Iraq it ranks the first among the population and the leading cause of cancer related female mortality. This study is designed to investigate the correlations between serum and tissue markers in order to clarify their role in progression or regression breast cancer. Tumor Markers are groups of substances, mainly proteins, produced from cancer cell or from other cells in the body in response to tumor. The study was carried out from April 2018 to April 2019 with total number of 60 breast cancer women. The blood samples were collected from breast cancer women in postoperative and pretherapeutic who attended teaching oncology hospital of the medical city in Baghdad and the serum markers evaluated by ELISA technique are Carbohydrate Antigen 15-3 (Ca 15-3), Carbohydrate Antigen 27.29 (Ca 27.29), Anti-Mullerian Hormone (AMH), Tumor Necrosis Factor-Alpha (TNF-α), Interleukin-6 (IL-6), Interleukin-10 (IL-10) and Human Epidiymis Protein-4 (HE4). Tissue samples were collected for the same breast cancer women who attended medical city, Baghdad with total number 30. The tissue markers evaluated by Immunohistochemical technique are Estrogen Receptor (ER), Progesterone Receptor (PR), Human Epidermal Growth Factor Receptor 2 (Her 2/neu) and Cyclin E. The results showed a positive significant correlation (p = 0.017) between Ca 27.29 and Her-2/neu, (p = 0.038) between IL-6 and cyclin E phenotype, (p = 0.051) between TNF-α and Cyclin E intensity, (p = 0.005) between HE4 and Her-2/neu, and negative significant correlation (p = 0.058) between IL-10 and ER score and (p = 0.045) between HE4 with Cyclin E intensity. We conclude from these correlations that positive correlations increasing disease progression, like correlation between Ca 27.29 and Her-2/neu, cyclin E with IL-6 and cyclin E with TNF-α. And the negative correlations may contribute to delay disease, like correlation between IL-10 and ER. From the correlations results in this study, it is clear that the Ca 27.29, Her-2 / neu, cyclin E markers play an important role in disease progression.
السخرية والمفارقة في شعر احمد مطر
جاء ابن كثير في عصر نشط فيه التأليف في كل فن من فنون الدراسات الدينية والعربية، ومن الطبيعي أن يكون التأليف في ميدان السيرة النبوية مواكبًا لهذا النشاط الذي استقى مواده ونصوصه من الثروة الضخمة من الكتب والآراء والروايات التي سجلها العلماء والمحدثون والحفاظ قبل ذلك العصر.
يتناول هذا المقال تصورًا مستقبليًا لمؤسسات المعلومات في عام 2050، حيث يستعرض كيف ستتغير بنيتها لتصبح ذكية ومستدامة، ويستعرض دور أخصائي المعلومات في بيئة رقمية متقدمة. كما يناقش تطور مصادر المعلومات وخدماتها، ونُظم تنظيمها، بالإضافة إلى تنوع المستفيدين، مع إبراز دور هذه المؤسسات في دعم التنمية المستدامة
Введение
Международные контакты обусловили интерес к изучению основной формы общения – диалога. Форма диалога в каждом из контактирующих в процессе общения языков должна быть рассмотрена в разных аспектах – не только лингвистическом, но и социолингвистическом и этическом. Это объясняется тем, что в речевой коммуникации необходима как адекватность выражения мысли, так и соблюдение тради
... Show MoreDeveloping disorders or ingeneral disability considered one of infortant cases which socities faces as a case with several a spects that may lead to disability . the movement of growth anf developing in the society thus the gardiauship of abnormal individuals became insisting issue which has social and human necessity .
The children of autism considered as special categories that guardian ship and care started of them inhoticeble image at the last time .
Hence, the researcher interested in this problem that made her studying it the study aimed to educte the child of autism that exist in kindergarten .the resrarcher depended on (Adel Abdullah) test for child autism that consists o
... Show Moreدراسة طبيعة الاستراتيجية الامريكيه في اقليم جنوب آسيا وصراعات القوى الإقليمية الهند وباكستان
This research seeks to show the state of the sad female self in Iraqi women's poetry, reveal its psychological potential within the text, analyze the phenomenon of sadness and explain its presence in poetic texts, show the influences of social life, the turmoil that was the main resource for the crisis of the creative woman's self and how to confront it, explain the motives and reasons why the creative woman wrote about the sadness of herself through techniques and methods unique to her
The research came to a statement in explaining the impact of movement in general in the Arabic language, as a word and sentence, in the Holy Qur’an in particular, and the Arabic syntactic movement in understanding the Qur’anic text.
The research contained two sections. Each section has two demands, an introduction, and a preface. The most prominent titles of the research are the aspect of parsing, which is one of the characteristics of the Ḍād; the definition of parsing in language and terminology; the impact of movement on understanding the Arabic text in general; and in understanding the Qur’anic text in particular