Breast cancer is the most prevalent malignancy among women worldwide, in Iraq it ranks the first among the population and the leading cause of cancer related female mortality. This study is designed to investigate the correlations between serum and tissue markers in order to clarify their role in progression or regression breast cancer. Tumor Markers are groups of substances, mainly proteins, produced from cancer cell or from other cells in the body in response to tumor. The study was carried out from April 2018 to April 2019 with total number of 60 breast cancer women. The blood samples were collected from breast cancer women in postoperative and pretherapeutic who attended teaching oncology hospital of the medical city in Baghdad and the serum markers evaluated by ELISA technique are Carbohydrate Antigen 15-3 (Ca 15-3), Carbohydrate Antigen 27.29 (Ca 27.29), Anti-Mullerian Hormone (AMH), Tumor Necrosis Factor-Alpha (TNF-α), Interleukin-6 (IL-6), Interleukin-10 (IL-10) and Human Epidiymis Protein-4 (HE4). Tissue samples were collected for the same breast cancer women who attended medical city, Baghdad with total number 30. The tissue markers evaluated by Immunohistochemical technique are Estrogen Receptor (ER), Progesterone Receptor (PR), Human Epidermal Growth Factor Receptor 2 (Her 2/neu) and Cyclin E. The results showed a positive significant correlation (p = 0.017) between Ca 27.29 and Her-2/neu, (p = 0.038) between IL-6 and cyclin E phenotype, (p = 0.051) between TNF-α and Cyclin E intensity, (p = 0.005) between HE4 and Her-2/neu, and negative significant correlation (p = 0.058) between IL-10 and ER score and (p = 0.045) between HE4 with Cyclin E intensity. We conclude from these correlations that positive correlations increasing disease progression, like correlation between Ca 27.29 and Her-2/neu, cyclin E with IL-6 and cyclin E with TNF-α. And the negative correlations may contribute to delay disease, like correlation between IL-10 and ER. From the correlations results in this study, it is clear that the Ca 27.29, Her-2 / neu, cyclin E markers play an important role in disease progression.
الكندي هو ابو يوسف يعقوب بن اسحاق بن الصباح . كما هو عند ابن جلجل (1) بن عمران بن اسماعيل بن محمد بن الأشعث بن قيس الكندي . كما يضيف ابن النديم(2) كان أبوه اسحق بن الصباح أميرا ً على الكوفة للمهدي والرشيد . على ما يقرره ابن نباته المصري(3) ، كان جده الأشعت بن قيس من أصحاب النبي الكريم وكان قبل ذلك ملكا ً على جميع(كندة)
دور مكننة المعلومات المحاسبي في اتخاذ القرارات
This research is an attempt to prove the scientific tendency in the Islamic philosophical heritage through a review of the most important ideas of intellectual and philosophical theories brought by the philosophers of this
Praisebe to God, Lord of the worlds, and blessings and peace be upon the most honorable messengers, our Prophet Muhammad, may God bless him and granthim peace. And after
In this paper we will explain ,how use Bayesian procedure in analysis multiple linear regression model with missing data in variables X's as the new method suggest , and explain some of missing Patterns under missing mechanism , missing complete at random MCAR and compare Bayesian estimator with complete case estimator by use simulation procedure .
Parties as active units in this process in order to work must have access to sources of funding in order to maintain their political presence in society and participate in the process of electoral competition, To win the election, bolstering the huge role that money has played in influencing the principle of equality among contestants in the elections. Those who own money will have a greater chance of winning the elections while less competitive opportunities for others who do not own the money or what they own does not give them the competitive ability to win elections. From this point of view, controlling political finance through legal regulation and institutional, media and popular monitoring has become an important requirement
... Show MoreAll praise be to Allah, Lord of the worlds, and prayers and peace be upon the most honourable of the prophets and messengers, our beloved Muhammad, and on his family and companions until the Day of Judgment
This research is marked by "a look at the art of farming in Islam" to sign Mehdi Mohaqiq worthy of translation into Arabic because it is known in the arts and sciences of agriculture in the Islamic heritage, which was known and which has been translated into Arabic, has dealt with the following topics:
- The attention of Muslim scholars to study the works of Greece
- The discretion of the caliphs and the judges and the Senate Agriculture ordered
الفيدرالية : نظرة في منطلقاتها الفكرية وآفاقها المستقبلية
العلوم الاجتماعية في جامعة بغداد .. التاريخ والتطورات