Breast cancer is the most prevalent malignancy among women worldwide, in Iraq it ranks the first among the population and the leading cause of cancer related female mortality. This study is designed to investigate the correlations between serum and tissue markers in order to clarify their role in progression or regression breast cancer. Tumor Markers are groups of substances, mainly proteins, produced from cancer cell or from other cells in the body in response to tumor. The study was carried out from April 2018 to April 2019 with total number of 60 breast cancer women. The blood samples were collected from breast cancer women in postoperative and pretherapeutic who attended teaching oncology hospital of the medical city in Baghdad and the serum markers evaluated by ELISA technique are Carbohydrate Antigen 15-3 (Ca 15-3), Carbohydrate Antigen 27.29 (Ca 27.29), Anti-Mullerian Hormone (AMH), Tumor Necrosis Factor-Alpha (TNF-α), Interleukin-6 (IL-6), Interleukin-10 (IL-10) and Human Epidiymis Protein-4 (HE4). Tissue samples were collected for the same breast cancer women who attended medical city, Baghdad with total number 30. The tissue markers evaluated by Immunohistochemical technique are Estrogen Receptor (ER), Progesterone Receptor (PR), Human Epidermal Growth Factor Receptor 2 (Her 2/neu) and Cyclin E. The results showed a positive significant correlation (p = 0.017) between Ca 27.29 and Her-2/neu, (p = 0.038) between IL-6 and cyclin E phenotype, (p = 0.051) between TNF-α and Cyclin E intensity, (p = 0.005) between HE4 and Her-2/neu, and negative significant correlation (p = 0.058) between IL-10 and ER score and (p = 0.045) between HE4 with Cyclin E intensity. We conclude from these correlations that positive correlations increasing disease progression, like correlation between Ca 27.29 and Her-2/neu, cyclin E with IL-6 and cyclin E with TNF-α. And the negative correlations may contribute to delay disease, like correlation between IL-10 and ER. From the correlations results in this study, it is clear that the Ca 27.29, Her-2 / neu, cyclin E markers play an important role in disease progression.
The research aim is to identify the concept of fair value and its measurement approaches, shed light on the concept of fraud and its forms, motives, as well as how to identify fraud under the fair value method.
I have been using the program package SSPS statistical in the calculation of the research variables, and the research sample was a group of university professors and auditors working in the federal board of Supreme Audit.
The researcher has reached some conclusions, the most important; the lack of conclusive evidence about management's intent in adopting the use of fair value raises several doubts about the credibility of the statements prepared in under the fa
... Show Moreالمنظمات الدولية دراسة في منهجها وطبيعة فهمها
The method of request is one of the important rhetorical methods used by the creator in terms of rhetorical diversification, influence, artistic aesthetics and increasing textual coherence, and we tried through a group (Which torments are inferior) by the poet Majid Al-Rubaie, to shed light on these methods and their ability, displacement, relationality, direct and advertising interactions from them, and what they broadcast From metaphorical purposes is the second image of it, after its main image and title. This cohesion and harmony between the two images is an important and influential rhetorical trend.
Dans le romantisme et ses textes, il est important de mentionner qu'il n'existe qu'un seul thème romantique qui est l'amour, mais assez pour avoir fait du XIXème siècle, une révolution du texte romantique. L'amour consiste à la réduction de l'univers, à un seul être, puis la dilatation de ce seul être, voilà l'amour. cet amour passionnel n'est qu'un arrangement froid et réfléchi excluant d'emblée l'exaltation des sentiments. Néanmoins, cet amour passionnel peut être brutal. quant à la mort, dans le drame romantique, l'amour et la mort sont liés. Beaucoup d'histoires d'amour finissent le plus souvent par
... Show MoreThe semiotic approach to the unspoken seeks to analyze the text in an esoteric way, that is, to clarify what is hidden from it by reading between
There is no doubt that this topic has received more study and research than other analytical studies of contemporary poetry models, but many scholars did not stop at the limits of crystallizing the features of feminist poetic production, given its active role in building the features of the modern Arab literary entity.
We conclude that verbs in terms of the number of letters divided into abstract and enlarged
بصمات الذاكرة التاريخية في الحياة الوطنية العراقية
سار العباسيون على نفس النهج الذي كان عليه الأمويين في كثير من الانظمه والتقاليد والسياسات على الرغم من إن الدولة العباسية كانت تمثل بداية لعصر جديد في تاريخ الإسلام(1)،ومن تلك الأنظمة التي ورثوها عن الأمويين وطوروها هي اهتمامهم بالنظام الزراعي منذ بداية قيام دولتهم وهنا سنحاول تقديم بعض الانجازات
تعد مسالة بناء الدولة احدة المواضيع المهمة في حقل الدراسات السياسية والتي تعكس مظهراً متعدد الابعاد لمبدأ الثقة المنشود بين الحاكم والمحكوم، فمنذ أمد طويل تحاول الدول تحقيق تنميتها السياسية والبحث عن مقومات ترشيد سياسي لقدراتها المؤسساتية والوظيفية بهدف تعزيز اسس التكامل والاندماج بين المجتمع السياسي والمجتمع المدني. عليه انطلق جون راولز في مفهومه لبناء الدولة المعاصرة من بناء المجتمع العادل، فالعدالة ه
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