Breast cancer is the most prevalent malignancy among women worldwide, in Iraq it ranks the first among the population and the leading cause of cancer related female mortality. This study is designed to investigate the correlations between serum and tissue markers in order to clarify their role in progression or regression breast cancer. Tumor Markers are groups of substances, mainly proteins, produced from cancer cell or from other cells in the body in response to tumor. The study was carried out from April 2018 to April 2019 with total number of 60 breast cancer women. The blood samples were collected from breast cancer women in postoperative and pretherapeutic who attended teaching oncology hospital of the medical city in Baghdad and the serum markers evaluated by ELISA technique are Carbohydrate Antigen 15-3 (Ca 15-3), Carbohydrate Antigen 27.29 (Ca 27.29), Anti-Mullerian Hormone (AMH), Tumor Necrosis Factor-Alpha (TNF-α), Interleukin-6 (IL-6), Interleukin-10 (IL-10) and Human Epidiymis Protein-4 (HE4). Tissue samples were collected for the same breast cancer women who attended medical city, Baghdad with total number 30. The tissue markers evaluated by Immunohistochemical technique are Estrogen Receptor (ER), Progesterone Receptor (PR), Human Epidermal Growth Factor Receptor 2 (Her 2/neu) and Cyclin E. The results showed a positive significant correlation (p = 0.017) between Ca 27.29 and Her-2/neu, (p = 0.038) between IL-6 and cyclin E phenotype, (p = 0.051) between TNF-α and Cyclin E intensity, (p = 0.005) between HE4 and Her-2/neu, and negative significant correlation (p = 0.058) between IL-10 and ER score and (p = 0.045) between HE4 with Cyclin E intensity. We conclude from these correlations that positive correlations increasing disease progression, like correlation between Ca 27.29 and Her-2/neu, cyclin E with IL-6 and cyclin E with TNF-α. And the negative correlations may contribute to delay disease, like correlation between IL-10 and ER. From the correlations results in this study, it is clear that the Ca 27.29, Her-2 / neu, cyclin E markers play an important role in disease progression.
This paper generalizes and improves the results of Margenstren, by proving that the number of -practical numbers which is defined by has a lower bound in terms of . This bound is more sharper than Mangenstern bound when Further general results are given for the existence of -practical numbers, by proving that the interval contains a -practical for all
The housing sector in Iraq has suffered from multiple problems, the most prominent of which is the failure of the housing market to achieve housing production that faces population increases and a high number of households.
The research aims to foresight the future of the housing sector, and to identify the expectations of experts in the development of the housing sector and housing production, in order to overcome the obstacles and problems.
Foresight does not mean forecasting about future events, but rather it is a process and skill aimed at familiarity with providing sufficient knowledge to achieve the desired future goals, Accordingly, adopting a method of future foresight will reduce error, surprise and s
... Show MoreThe indicators were important core for any work, and may be occurring this indicators way of communicating among planers and decision makers, even also for public participating, do make any decision. The urban and regional planning is one of those science highly depending on using indictors, for two reasons, first, way to communicating ideas between specialist and non-specialist, (politician and decision makers), the second one, this field are multidisciplinary science, so the need indictors to clearing thoughts among different backgrounds in one team, as common language.
This research tries to clear importance of GIS in forming and building Spatial Planning Indicators, to cross communication problem among planning g
... Show MoreThis study examines the remaining architectural features in Kirkuk Castle,which does not include the heritage buildings outside it. The castle's fortifications are limited about military samples of the city during the Ottoman era ,concentrating on the importance remains of the walls that held on the edge of the hill leads to the interior, As well as some religious buildings such as mosques, shrines and churches, and the service buildings with most important caesarean dating back to the Seljuk era and a range of housing The importance of the subject lies in the study of these buildings , documentation, and knowledge of the designs and models of building to make it a link in the series of the late Islamic architecture
تنتاب العلاقةَ الأمريكية الإيرانية تجاذباتٌ ومشاحنات أدخلت العالم في حالة من الغموض السياسي، وجعلت بعض المراقبين والمحللين السياسيين لا يستبعدون توجيه الولايات المتحدة الأمريكية أو إسرائيل ضربة عسكرية لإيران، إذ يرى المدقق في واقع تلك العلاقة المضطربة: أن الأمور كلما بلغت حافة الهاوية عادت من جديد إلى ساحة الحوار والمفاوضات، ويبدو: أن الإستراتيجية الأمريكية التي يتبعها الرئيس (باراك أو
... Show MoreThe God Almighty prefer on the Arab nation, and entrusted to carry his message to the secular world as a whole, , gave her all necessities of life in terms of location, who are the heart in the earth's surface. From this blessed place emerged the greatest civilizations and the world has ever known for it than in human history, a four empires Alsamyat
ان علاقة وسائل الإعلام بحل الصراعات وبناء السلام المجتمعي كأحد الموضوعات المهمة التي تربط بين مجالي العلاقات الدولية والدراسات الإعلامية. ويعود مصطلح صحافة السلام إلى السبعينيات من القرن العشرين حيث يقدم هذه المفهوم مدخلا جديدا للإعلاميين يمُكنهم من البحث في الأسباب البنائية والثقافية للصراع ومدى تأثيره على حياة المواطنين وتقديم المضمون الذي يعكس القواسم المشتركة بين كافة أطراف الصراع في مجتمع معين وطر
... Show Moreالتجربة الاتحادية في دولة الامارات العربية المتحدة
مفهوم البعد الواحد في الرسم العراقي المعاصر
The historical documentation of the architectural archeology has a fundamental and great importance in evaluating the architectural product that has suffered from neglect