Breast cancer is the most prevalent malignancy among women worldwide, in Iraq it ranks the first among the population and the leading cause of cancer related female mortality. This study is designed to investigate the correlations between serum and tissue markers in order to clarify their role in progression or regression breast cancer. Tumor Markers are groups of substances, mainly proteins, produced from cancer cell or from other cells in the body in response to tumor. The study was carried out from April 2018 to April 2019 with total number of 60 breast cancer women. The blood samples were collected from breast cancer women in postoperative and pretherapeutic who attended teaching oncology hospital of the medical city in Baghdad and the serum markers evaluated by ELISA technique are Carbohydrate Antigen 15-3 (Ca 15-3), Carbohydrate Antigen 27.29 (Ca 27.29), Anti-Mullerian Hormone (AMH), Tumor Necrosis Factor-Alpha (TNF-α), Interleukin-6 (IL-6), Interleukin-10 (IL-10) and Human Epidiymis Protein-4 (HE4). Tissue samples were collected for the same breast cancer women who attended medical city, Baghdad with total number 30. The tissue markers evaluated by Immunohistochemical technique are Estrogen Receptor (ER), Progesterone Receptor (PR), Human Epidermal Growth Factor Receptor 2 (Her 2/neu) and Cyclin E. The results showed a positive significant correlation (p = 0.017) between Ca 27.29 and Her-2/neu, (p = 0.038) between IL-6 and cyclin E phenotype, (p = 0.051) between TNF-α and Cyclin E intensity, (p = 0.005) between HE4 and Her-2/neu, and negative significant correlation (p = 0.058) between IL-10 and ER score and (p = 0.045) between HE4 with Cyclin E intensity. We conclude from these correlations that positive correlations increasing disease progression, like correlation between Ca 27.29 and Her-2/neu, cyclin E with IL-6 and cyclin E with TNF-α. And the negative correlations may contribute to delay disease, like correlation between IL-10 and ER. From the correlations results in this study, it is clear that the Ca 27.29, Her-2 / neu, cyclin E markers play an important role in disease progression.
Studying and considering the text of the holy Quran is a task of necessity which needs a valuable as well as reliable contribution from all the concerned parties because of the greatness of this holy and scared text. The text of the holy Quran
دراسة التفكير الاستراتيجي وأبعاده وأثره في تمكين الموارد البشرية
تواجه المنظمات فــي القرن الحالي تحديات جديدة تختلف عــن تلك التــي كانت تواجهها خلال العقود المنصرمة، مما يستدعي الحاجة للتجديد التنظيمي واكتساب ميزة استراتيجية والاحتفاظ بمعرفـة عالية، لقد غدا الكثير من المفكرين والباحثين والمستشارين والمديرين يعتبرون المعرفـة المورد الاساس للميزة التنافسية بدلا" من رأس المال واصبحت الموجودات المادية ذات قيمة محدودة ما لم يعرف الافراد ماذا يفعلون بها، وهكذا فأن
... Show Moreان العولمة هي ظاهرة العصر وبحكم شمولية ابعادها وعمق اثارها اصبحت قضيتها تثير جدلا واسعا بين الباحثين (واصحاب القرار) متضمنا المصطلح والمفهوم والتجليات والمضمون والوسائل والاهداف، ولقد بدأت ملامح وخصائص هذه الظاهرة تتسارع لتشكل الهندسة الجديدة لاقتصاد القرن الحادي والعشرين وفي ظل هذا الاتجاه نحو تقسيم العمل الدولي ظهرت نتائج ومزايا عكست مديات التغيرات على مجمل الحياة الاقتصادية والاجتماعية للمجتمعا
... Show MoreThe aim of this paper is to determine the effect of internal marketing through three dimensions: vision, development, and reward - on organizational citizenship behavior in three private universities in Iraq. Organizations’ view of their members as internal customers could be made them more realistic in dealing with the reasons for leaving and going to other organizations. This can promote business organizations to build an organizational environment that contributes to making the organization look like the homeland of those workers. The research method is descriptive and analytical. The tool for data collection was the questionnaire. Statistical software (SPSS V.23 and AMOS V.23) was used to analyze the data. The research sample was r
... Show Moreيتكون العالم ، أنذاك ، من دارين - دار الإسلام حيث الأقاليم الإسلامية ودار الحربوهي بلاد المشركين الذين لا صلح بينهم وبين المسلمين (1) ، أي ما خضع للعدو ضمن حدود سيادته ، ولكن عندما يحتفظ أهالي البلاد المفتوحة صلحاً بحقوق ملكية الأرض فأنه ،على رأي الماوردي ، يصبح خراجهم جزية ولا جزية على رؤوسهم(2) ولهم حرية تبايع أرضهم فيما بينهم أو بيعها للمسلمين أو لأهل الذمة (3) . ولا يمكن أن تعد أرضهم
... Show Moreظهر التقييس كمفهوم لقياس الضرائب وتحديد الأجور والرواتب منذ مدة ليست طويلة وتم استخدامه في العديد من بلدان العالم. ولاجل تحقيق العدالة في توزيع الدخول ورفع المستوى المعيشي لذوي الدخول المحدودة، اذ يتطلب من الدولة إتباع أسلوب التقييس للأجور والرواتب للموظفين ،إضافة إلى استخدام التقييس في فرض الضرائب وتحديد السماحات اعتمادا على مستوى التضخم في الاقتصاد. خاصة وان الهدف الأساسي من إتباع أسلوب التقييس هو
... Show Morethe subject of medical activity in eras Rashidi and Umayyad is one of the most important for study because Medicine is related to human life and health Medicine is important science which should be identified and interested. the Prophet Muhammad emphasized God bless him and to pay attention to the study of medicine through the Hadith.
From the above can be placed in a summary of the Iraqi personal to the subject in the context of urban family Integration: As personal so hard and durable organization to some extent on the nature of the individual temperament, his mind and his body structure Vhoalve determines the unique environment compatibility.
Valchksah not inherited However, the inherited components, building of the body of the individual and the way they complement each other and members of Trivhalta functions performed by temperament and preparations all in compliance with Vchksath become a product of the interaction between the possibility of nature and the environment.
From here we can say that the family a big role in the personal configuration,
Quran is a basic reference of production it is as a source to all sciences, Ayat of Quran would mention the importance of benefits of animals. Quran contain full surrat named in animal names as Al-Baqara that is to clarify its benefits and importance in human’s life.