The apoptotic activity of methionine γ- lyase from Pseudomonas putida on cancer cell lines was indicated by measuring the concentration of cytochrome c in the supernatants of cell lines. The result revealed high concentration of cytochrome c in the supernatants of cancer cell lines (RD, AMGM and AMN3) respectively while the concentration of anti-apoptotic protein (Bcl-2) was very low.

Let R be a prime ring and δ a right (σ,τ)-derivation on R. In the present paper we will prove the following results:
First, suppose that R is a prime ring and I a non-zero ideal of R if δ acts as a homomorphism on I then δ=0 on R, and if δ acts an anti- homomorphism on I then either δ=0 on R or R is commutative.
Second, suppose that R is 2-torsion-free prime ring and J a non-zero Jordan ideal and a subring of R, if δ acts as a homomorphism on J then δ=0 on J, and if δ acts an anti- homomorphism on J then either δ=0 on J or J
Z(R).

Let R be a commutative ring with 1 and M be a (left) unitary R – module. This essay gives generalizations for the notions prime module and some concepts related to it. We termed an R – module M as semi-essentially prime if annR (M) = annR (N) for every non-zero semi-essential submodules N of M. Given some of their advantages characterizations and examples, and we study the relation between these and some classes of modules.

Our active aim in this paper is to prove the following Let Ŕ be a ring having an
idempotent element e(e  0,e 1) . Suppose that R is a subring of Ŕ which
satisfies:
(i) eR  R and Re  R .
(ii) xR  0 implies x  0 .
(iii ) eRx  0 implies x  0( and hence Rx  0 implies x  0) .
(iv) exeR(1 e)  0 implies exe  0 .
If D is a derivable map of R satisfying D(R )  R ;i, j 1,2. ij ij Then D is
additive. This extend Daif's result to the case R need not contain any non-zero
idempotent element.

     Let R1be a commutative2ring with identity and M be a unitary R-module. In this6work we7present almost pure8ideal (submodule) concept as a9generalization of pure10ideal (submodule).  lso, we1generalize some9properties of8almost pure ideal (submodule). The 7study is almost regular6ring (R-module).

In this paper, the concept of Jordan triple higher -homomorphisms on prime

rings is introduced.  A result of Herstein is extended on this concept from the ring  into the prime ring .  We prove that every Jordan triple higher -homomorphism of ring  into prime ring  is either triple higher -homomorphism  or triple higher -anti-homomorphism of  into .

This study was design to characterize the immune response in experimentally Pseudomonas aeruginosa mastitis mice treated probiotic bifidocin and cazacin of Bifidobacterium spp. and Lactobacillus casei. We quantified the level of the IFN-γ and TNF-α cytokines in blood by ELISA technique. IFN-γ level was significantly higher in infected group compared to control (340.21 ± 41.61, 8.45 ± 0.83 pg/ml, respectively). While the level of IFN-γ was significantly higher in mastitis mice than bifidocin and cazacin treated mice. Also, TNF-α level showed a significant increase in mastitis mice compared to controls (320.11±40.33, 8.45±0.83pg/ml, respectively). Among mastitis and bifidocin (9 and 18 mg/ml), cazacin (11 and 22 mg/ml) treate

Let R be a semiprime ring with center Z(R) and U be a nonzero ideal of R. An additive mappings are called right centralizer if ( ) ( ) and ( ) ( ) holds for all . In the present paper, we introduce the concepts of generalized strong commutativity centralizers preserving and generalized strong cocommutativity preserving centralizers and we prove that R contains a nonzero central ideal if any one of the following conditions holds: (i) ( ) ( ), (ii) [ ( ) ( )] , (iii) [ ( ) ( )] [ ], (iv) ( ) ( ) , (v) ( ) ( ) , (vi) [ ( ) ( )] , (vii) ( ) ( ) ( ), (viii) ( ) ( ) for all .

     This paper develops the work of Mary Florence et.al. on centralizer of semiprime semirings and presents reverse centralizer of semirings with several propositions and lemmas. Also introduces the notion of dependent element and free actions on semirings with some results of free action of centralizer and reverse centralizer on semiprime semirings and some another mappings.

Nilpotency of Centralizers in Prime Rings