Background: The base of the denture is largely responsible for providing the prosthesis with retention, stability, and support by being closely adapted to the oral mucosa. However; the process of bone resorption is irreversible and may lead to an inadequate fit of the prosthesis; this can be overcome by relining. Materials and methods: Acrylic based soft denture liner is prepared by preparing polymer from purified methylmethacrylate monomer with (10-2) initiator and (30%) dibutylphthalate plasticizer concentrations. Biological properties were evaluated in comparison with the control material through subcutaneous specimens' implantation in the New Zealand rabbits. Excisional biopsies were taken after (1, 3, days 1, 2, 3, 4 weeks) period. Microscopically, sections are studied to explore the consequences of thecontact with tested material and tissue response. Tensile strength, percentage of elongation, compressive, bond, and peel strengthwere evaluated; as well as water sorption and solubility is compared with the control material. Results: Histological study of the sections contained experimental and control materials showed normal tissue response by normal infiltration of the inflammatory cells; acute in the first days then chronic inflammatory cells were seen in the subsequent periods. Finally capsular enclosure of the specimens was well characterized and seen after 4 weeks. Results of the mechanical properties showed non-significant differences for the tested properties except the percentage of elongation; control material recorded significantly higher value. Moreover, statistically; water sorption of the experimental material was significantly lower than the control material; while the tested materials showed non-significant differences regarding the solubility test. Conclusion: The recommended formula of preparing heat-cured; acrylic based denture soft liner showed acceptable properties. Further evaluations of the experimental material were suggested.
This work investigates the effect of the gas nitriding process on the surface layer microstructure and mechanical properties for steel 37, tool steel X155CrVMo12-1 and stainless steel 316L. Nitriding was conducted at a temperature of 550 °C for 2 hours during the first stage and at 750 °C for 4 hours during the second stage. SEM and X-ray diffraction tests were performed to evaluate the microstructural features and the major phases formed after surface treatment. SEM and X-ray diffraction tests were performed to assess the microstructural features and the primary phases formed after surface treatment. The new secondary precipitates were identified as γ′-Fe4N, ε (Fe2–3N), and α-Fe, exhibiting an uneven chain-like pattern wit
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Lasmiditan (LAS) is a recently developed antimigraine drug and was approved in October, 2019 for the treatment of acute migraines; however, it suffers from low oral bioavailability, which is around 40%.
This study aimed to improve the LAS bioavailability via formulation as nanoemulsionbased in situ gel (NEIG) given intranasally and then compare the traditional aqueous-LASsuspension (AQS) with the two successful intranasal prepared formulations (NEIG 2 and NEIG 5) in order to determine its relative bioavailability (F-relative) via using rabbits.
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This paper displays the effect of uncoated and coated chopped carbon fibers with alumina Al2O3 or Tri calcium phosphate (TCP) on the impact strength of acrylic poly methyl methacrylate (PMMA) denture base resin. To improve bonding between carbon fibers and coating materials powders, the surface of carbon fibers has been treated with Para amino benzoic acid (C9H10N2O3) and poly vinyl alcohol (PVA) was also used. The morphology of the coating layers has been examined by field emission scanning electron microscope (FE-SEM). From the results, PMMA reinforced with uncoated chopped carbon fiber has high impact strength value but still have bad aesthetic. Samples prepared b
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In this work a novel drug delivery system through modification of poly acrylic acid with Methionine as a spacer between the poly acrylic acid which was converted to its acyl chloride and reacted with Methionine as spacer unit which has been reacted with Ampicillin drug. In vitro drug release study had been conducted successfully in basic medium in pH 7.4 and acidic medium in pH 1.1 at 37?. Due to many problems associated with drug release and, this modification could decrease the side effect of drug. The prepared prodrug polymer was characterized by spectra method [FTIR and 1H?NMR]. Physical properties and intrinsic viscosity of drug polymer were determined. The good results were obtained in the presence of spacer unit with compar
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In this work we explain and discuss new notion of fibrewise topological spaces, calledfibrewise soft ideal topological spaces, Also, we show the notions of fibrewise closed soft ideal topological spaces, fibrewise open soft ideal topological spaces and fibrewise soft near ideal topological spaces.
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In this paper, the C̆ech fuzzy soft closure spaces are defined and their basic properties are studied. Closed (respectively, open) fuzzy soft sets is defined in C̆ech fuzzy-soft closure spaces. It has been shown that for each C̆ech fuzzy soft closure space there is an associated fuzzy soft topological space. In addition, the concepts of a subspace and a sum are defined in C̆ech fuzzy soft closure space. Finally, fuzzy soft continuous (respectively, open and closed) mapping between C̆ech fuzzy soft closure spaces are introduced. Mathematics Subject Classification: 54A40, 54B05, 54C05.
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