Rheumatoid arthritis (RA), is an autoimmune, and inflammatory disease that is closely related to the destruction of cartilage and bone. DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. Recent evidence has demonstrated that DC-SIGN is involved in the pathophysiological of chronic inflammation, so DC-SIGN has been linked to several autoimmune and may play an essential indicator in the pathogenesis and progression of RA. Therefore, the purpose of this study is to determine the serum level of DC-SIGN in RA patients, as well as the level of DC-SIGN based on demographic characteristics. Fifty Iraqi RA patients were enrolled in the study, and a control sample of 38 healthy individuals (ascertain by laboratory and clinical tests) were included and matched by gender, age, and ethnicity with the patients. The DC-SIGN concentration was calculated in the patients’ serum and compared to control using the ELISA assay and the results revealed significantly increased serum level of DC-SIGN (12.047 ± 1.114 vs. 6.863 ± 0.806 ng/ml) was recorded in RA patients compared to controls. When correlating results, it was shown that the concentration of DC-SIGN in the serum did not record a significant difference between gender and age, as well as the blood groups. To determine the impact of the therapeutic status in RA patients on the DC-SIGN level, it was found that the concentration of DC-SIGN level was higher in untreated patients compared to treated patients. Regarding viral infection, when an investigation was conducted in RA patients infected with SARS-CoV-2, the serum level of DC-SIGN in RA patients with COVID-19 showed no change in concentrations compared to uninfected RA patients.
The organization is affected by and affects the attending environment. Whereas the accounting information system is one of the informational systems existing in any organization.
The research partake capability of developing information system in economic units through design “A Integrated System of Accounting and Management Information “to enable using the relationships of an integrated from all subsystems in economic unit specially: Accounting Information System (AIS) and Management Information System (MIS).
Also the research partake a set of basic requisites that will contribute in application An Integrated System of Accounting and Management Informat
... Show Moreكان لسياسات االحتالل دور بارز في فشل مشروع إعادة بناء الدولة في افغانستان، وفي الوقت نفسه تتحمل دول االحتالل المسؤ و لية الكاملة عن بعض هذه ً كبي ارً السياسات مثل عدم التخطيط الجيد لمرحلة االحتالل وإعادة بناء الدول ة، ثم إن جزءا من فشل هذه السياسات يرجع الى البيئتين المحلية واإلقليمية ، كذلك كان للخبرة السياسية والدستورية وللواقع االجتماعي الثقافي األفغاني تأثيرهما المهم في قدرة المجتمع األفغاني ً على قبول
... Show MoreThe emergence of e-marketing to make the world a small village does not comply with barriers, the place nor the time, which led to the transformation of marketing in various service sectors, regional and international general and the insurance sector, especially from traditional marketing to electronic marketing, bringing e-marketing of insurance services is the effective tool to achieve for growth, was able to jump to the overall marketing efforts to the contemporary trends in line with the current and its variables, and this significant acceleration in technological development has made insurance companies are racing to offer their insurance services on the latest applications of modern technology through multiple sites on the Internet
... Show Moreفي ظل التطورات التقنية التي حدثت خلال السنوات القليلة الماضية ومحاولة الإستفادة من تطور هذه التقنيات في مختلف مجالات الحياة، سعى العديد من منظمات الأعمال ـ بمختلف نشاطاتها وهياكلها القانونية ـ لتوظيف أعمالها بالإستفادة من تقنيات المعلومات ـ بمختلف أنواعهاـ وظهر مفهوم جديد في التعاملات أطلق عليه "التجارة الإلكترونية".وبما أن أية وحدة اقتصادية تعمل ضمن نظام مفتوح يؤثر و
... Show Moreهدف البحث إلى التعرف على مستوى الازدهار النفسي فضلاً عن التعرف على الفروق في مستوى الازدهار النفسي بين الطلبة على وفق الجنس (ذكر – انثى) والتخصص الدراسي (علمي – انساني) والمرحلة الدراسية (أول- رابع)، تألفت عينة البحث من (300) طالبا وطالبة من طلبة جامعة بغداد، وتم تطبيق مقياس البحث - مقياس (الازدهار النفسي) وهو (من إعداد الباحثة)، وقد اسفرت نتائج البحث عن: - إن طلبة الجامعة لديهم مستوى ازدهار نفسي عال. - عدم وجود فروق ف
... Show MoreBekanntlich hat jede Sprache ihre eigenen charakteristischen Besonderheiten. Davon ausgehend gibt es auch gewisse Unterschiede zwischen dem Arabischen und dem Deutschen. Zu den wichtigsten Gebieten der deutschen Grammatik gehören die zusammengesetzten Sätze, vor allem Satzgefüge mit den über- und untergeordneten Sätzen. Dazu gehören auch die Äquivalente der Nebensätze, besonders die Infinitiv- und Partizipialkonstruktionen.
Die vorliegende Recherche hat eine der grammatischen Strukturen des Arabischen und des Deutschen nämlich die dass-Sätze und Infintivsätze mit zu und deren Wiedergabemöglichkeiten in den beiden Sprachen zum Inhalt, weil die Infinitivsätze mit zu den Deutschlernenden beson
... Show MoreFood comes after air and water in terms of importance in the survival of human beings, In addition, it is the support and strength of health and support, if lost or destroyed man would die or get sick and become a heavy burden on himself and his society. Food, like other sources of life, is subject to various risks and corruption comes from countless sources. Among these dangers is the result of spontaneousness, lack of knowledge or compulsion due to the interaction of variables beyond the will of the producer and the consumer, such as pollution of water, air and environment and their reflection on food consumed by people. However, we can’t deny that some reasons of corruption are intentional and resulting from a planning in advance in
... Show MoreAssyrian merchants established in the second millennium BC Assyrian commercial settlements in Anatolia, and these settlements had a great cultural value