Rheumatoid arthritis (RA), is an autoimmune, and inflammatory disease that is closely related to the destruction of cartilage and bone. DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. Recent evidence has demonstrated that DC-SIGN is involved in the pathophysiological of chronic inflammation, so DC-SIGN has been linked to several autoimmune and may play an essential indicator in the pathogenesis and progression of RA. Therefore, the purpose of this study is to determine the serum level of DC-SIGN in RA patients, as well as the level of DC-SIGN based on demographic characteristics. Fifty Iraqi RA patients were enrolled in the study, and a control sample of 38 healthy individuals (ascertain by laboratory and clinical tests) were included and matched by gender, age, and ethnicity with the patients. The DC-SIGN concentration was calculated in the patients’ serum and compared to control using the ELISA assay and the results revealed significantly increased serum level of DC-SIGN (12.047 ± 1.114 vs. 6.863 ± 0.806 ng/ml) was recorded in RA patients compared to controls. When correlating results, it was shown that the concentration of DC-SIGN in the serum did not record a significant difference between gender and age, as well as the blood groups. To determine the impact of the therapeutic status in RA patients on the DC-SIGN level, it was found that the concentration of DC-SIGN level was higher in untreated patients compared to treated patients. Regarding viral infection, when an investigation was conducted in RA patients infected with SARS-CoV-2, the serum level of DC-SIGN in RA patients with COVID-19 showed no change in concentrations compared to uninfected RA patients.
This study deals with it the era of Taher Bin Al Hussein for his son Abdullah when preside Diyarbakir and Rabia in succession of ALMa`amoon Abbasi in the political and historical dimensions
تناول البحث موضوعاً شديد الأهمية وهو الأمن الاجتماعي منظور اليه في سياق الحماية الجنائية لأمن الدولة والتحديات التي يتعرض لها بعد حصول تغيير حاسم في أساليب الحرب. كما يقدم البحث تقسيماً مختلفاً لأجيال الحروب نقتصر على اربعة منها استناداً إلى التغيير في أهداف الحرب الاستراتيجية وليس إلى مجرد وسائل ارتكابها لان هذه الوسائل لا تصلح لوصف التغييرات الحقيقية في أنماط الحروب والاهداف التي تسعى إلى تحقيقها. ويؤكد
... Show Moreاستهدفت هذه الدراسة تحليل واقع الاقتصاد العراقي على خلفية تحليل القدرة التنافسية بما يفضي الى وضع ملامح عامة لإستراتيجية بناء للقدرة التنافسية الوطنية للنهوض بالواقع الاقتصادي. وقد افترضت الدراسة ان الاقتصاد العراقي يعاني من اخفاقات شديدة في الاداء لا تتصل بطبيعته ولاتعتبر سمة اصيلة من سماته بل هي ظرفية وطارئة رغم وجودها منذ عقود.
ان حالة الوهن المرافق للفعاليات الاقتصادية تتصل بغيا
... Show MoreThis search in the virtues of the daughter of the Prophet Muhammad, to read on their boards want to recount loving and faithful), as stated in the introduction to the author, Abdullah Bin Ibrahim Al-Mirghani (D. 1207 H.) to give reasons in writing the manuscript, which was of an introduction and three chapters and a conclusion was the first in the door thanks to the great lady and on her birthday and her marriage and her death and subsequent events and the third in her them prayers and then the finale which was in love with the Prophet and calling for God to pardon and forgiveness and a good end. I was interested in this manuscript by Mirghani, Hadith and all accounts in reference to the virtues of the great lady to examine a manuscript
... Show Moreأشارت الجهود المعرفية السابقة إلى وجود اهتمام متزايد بالجماعات (Groups) على أساس أنها اللبنات الأساسية لقيام المنظمات. وقد فرض تعدد المنظمات في المجتمعات المعاصرة وتباينها من حيث أهدافها وطبيعة نشاطها، تجزئة فعالياتها إلى تخصصات عدة على وفق إطار تقسيم العمل، وبما أدى إلى تقسيم الأفراد العاملين إلى جماعات مختلفة في أدائها وأحجامها وشكلها، والتي تعمل جميعها لتحقيق هدف&
... Show MoreFraud crimes, which is a form of crimes against the funds in public office, is one of the crimes of traditional and cutting-edge in the same time, but it took a distinct character from other traditional crimes because of what is based upon, behavioral fundamentals and foundations and expressive image of personal qualities, concentrated in the mental work, the inventive sophistication, and skillful abilities of the perpetrators of these crimes, in addition to what is owned by crooks today a behavioral ability represented in underestimating laws and instructions. Fraud is considered one of the organized crime methods It is the most important method of its methods, all crimes practiced by the cro
... Show MoreConstruction projects have become a changing dramatically in recent decades and that the goal of the beneficiaries of the implementation of structural project is to complete the work with less time and within the cost of the specific and the best possible quality may sometimes happen that highlights the importance of time on the rest of the items at the implementation of projects for various reasons, including the need to use the project as soon as possible possible change rapidly to customer's requests, but the high cost of the project represents the biggest obstacle for entrepreneurs with its effects on the quality and the time workers, and is a measure of those elements in monetary terms is the key to integration between them, so the
... Show MoreComputational linguistics is a modern branch of linguistics concerned with computer processing of natural languages. It makes computer as human brain simulate to human mind to understand language endoscopy and application. It stems from the use of computers to create programs and information systems that help the user to solve linguistic issues such as translation, analysis, parsing, and others This research seeks to show the employability of Arabic grammar, especially the past tense of it, in the light of this theory The study made use of the computer program (Madamera) to apply its samples of past phrasal verbs, In its methodology
Whatever forms embodied in nature or in the product by forming elements, Kahadjom, fonts, and colors that characterized that her aesthetic and expressive values evoked to multiple indications of which are unequivocal, including what is iconic. Each one of these constituent elements of her form of extreme importance