Rheumatoid arthritis (RA), is an autoimmune, and inflammatory disease that is closely related to the destruction of cartilage and bone. DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. Recent evidence has demonstrated that DC-SIGN is involved in the pathophysiological of chronic inflammation, so DC-SIGN has been linked to several autoimmune and may play an essential indicator in the pathogenesis and progression of RA. Therefore, the purpose of this study is to determine the serum level of DC-SIGN in RA patients, as well as the level of DC-SIGN based on demographic characteristics. Fifty Iraqi RA patients were enrolled in the study, and a control sample of 38 healthy individuals (ascertain by laboratory and clinical tests) were included and matched by gender, age, and ethnicity with the patients. The DC-SIGN concentration was calculated in the patients’ serum and compared to control using the ELISA assay and the results revealed significantly increased serum level of DC-SIGN (12.047 ± 1.114 vs. 6.863 ± 0.806 ng/ml) was recorded in RA patients compared to controls. When correlating results, it was shown that the concentration of DC-SIGN in the serum did not record a significant difference between gender and age, as well as the blood groups. To determine the impact of the therapeutic status in RA patients on the DC-SIGN level, it was found that the concentration of DC-SIGN level was higher in untreated patients compared to treated patients. Regarding viral infection, when an investigation was conducted in RA patients infected with SARS-CoV-2, the serum level of DC-SIGN in RA patients with COVID-19 showed no change in concentrations compared to uninfected RA patients.
يُسلط البحث الضوء على الدور الجيواستراتيجي للمرأة في مجالي الإغاثة والتنمية ضمن نظام الحوكمة الصحية الدولية، متخذاً من منظمة الصحة العالمية (WHO) أنموذجاً تحليلياً لتقييم فاعلية العمل الإنساني. تنطلق الدراسة من إشكالية "المفارقة الهيكلية"؛ ففي حين تُشكل المرأة (70%) من القوى العاملة وتمثل فاعلاً محورياً وعنصراً حاسماً لامتصاص الصدمات ومنع تفكك النظم المجتمعية في بؤر الأزمات المعقدة (كما أثبتت النماذج في غزة، ا
... Show Moreصوت أهمية في العمل الإبداعي مثلما له الأهمية نفسها في عملية نقد هذا العمل لما تترتب عليه من آثار نطقية معبّرة، وبهذا يكون عملا هامّا في تنسيق البناء الفني العام للقصيدة، بوصف اللغة ظاهرة صوتية والكتابة تعبيرا عن ذلك النظام الصوتي.
After the twenty – first century become necessary for us motorcade era in educational a chevements by searching for the best strategies and teaching methods and techniques artotalbagesh resorting to the strategy
Did not use in use in the teaching of the foreseeable material general by voice and teaching perspective for the student of the class fourth science
In particular ,so the researcher asking the question follows:
Can the peer education strategy to have an impact in perspective drawing skill development ?
From here it demonstrated the importance of current research know the impact of p
... Show MoreMilling Machining is a widely accepted nontraditional machining technique used to produce parts with complex shapes and configurations. The material is removed in two stages roughing and finishing, the flat end cutter removed the unwanted part of material, then finished by end mill cutter. In milling technique, the role of machining factors such as cutting depth, spindle speed and feed has been studied using Taguchi technique to find its effectiveness on surface roughness. Practical procedure is done by Taguchi Standard matrix. CNC milling is the most conventional process which is used for removing of material from workpiece to perform the needed shapes. The results and relations indicate that the rate of feed is v
... Show MoreComputational linguistics is a modern branch of linguistics concerned with computer processing of natural languages. It makes computer as human brain simulate to human mind to understand language endoscopy and application. It stems from the use of computers to create programs and information systems that help the user to solve linguistic issues such as translation, analysis, parsing, and others This research seeks to show the employability of Arabic grammar, especially the past tense of it, in the light of this theory The study made use of the computer program (Madamera) to apply its samples of past phrasal verbs, In its methodology
The wisdom of the Creator ensures the call of every prophet with a miracle that would be something beyond what is familiar from the customs
جاء التقويم ليكون مكملا للعمليات التعليمية يساعد على الوقوف على نتائجها وسبل النهوض بها والوقوف على المعوقات التي تقف امام مسيرتها وقد عنيت عمليات التقويم باهتمام كبير من قبل القائمين على العمليات التعليمية اذ عقدت العديد من المؤتمرات والندوات واجريت العديد من الدراسات عالميا ومحليا من اجل الوقوف على هذه العملية المهمة الداعمة للتعليم والنهوض بمستويات المتعلمين ، ومن بي
... Show MoreHere is a professional and precise English translation of the text, formatted for clarity and academic/report standards: ## Translation Sustainable management of irrigation water is one of the most critical challenges facing the agricultural sector in Iraq, including the Al-Mahmoudiya district. As a vital rural and agricultural area, Al-Mahmoudiya relies on agriculture as a primary source of livelihood, particularly for cultivating grains, vegetables, and certain horticultural crops. Farmers in the district mainly depend on the Tigris and Euphrates rivers and their branching canals, as well as groundwater in certain areas. However, the prevailing irrigation methods remain traditional, leading to significant water waste and low water-use e
... Show Moreالمقدمة Introduction شهد العالم في العقود الأخيرة تطورًا مذهلًا في تقنيات الثورة الرقمية، وفي مقدمتها الذكاء الاصطناعي، الذي يُعد اليوم أحد أكثر مظاهر الكيانات الرقمية تقدمًا وإثارة للجدل. فقد تجاوز الذكاء الاصطناعي كونه أداة برمجية تُستخدم لإتمام مهام بسيطة، وأضحى فاعلًا رقميًا له تأثير حاسم في مجالات متعددة، كالصحة، والصناعة، والتعليم، والعدالة، والأمن، والعلاقات الاجتماعية، وغيرها. وقد بات من المألوف الحد
... Show More