Rheumatoid arthritis (RA), is an autoimmune, and inflammatory disease that is closely related to the destruction of cartilage and bone. DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. Recent evidence has demonstrated that DC-SIGN is involved in the pathophysiological of chronic inflammation, so DC-SIGN has been linked to several autoimmune and may play an essential indicator in the pathogenesis and progression of RA. Therefore, the purpose of this study is to determine the serum level of DC-SIGN in RA patients, as well as the level of DC-SIGN based on demographic characteristics. Fifty Iraqi RA patients were enrolled in the study, and a control sample of 38 healthy individuals (ascertain by laboratory and clinical tests) were included and matched by gender, age, and ethnicity with the patients. The DC-SIGN concentration was calculated in the patients’ serum and compared to control using the ELISA assay and the results revealed significantly increased serum level of DC-SIGN (12.047 ± 1.114 vs. 6.863 ± 0.806 ng/ml) was recorded in RA patients compared to controls. When correlating results, it was shown that the concentration of DC-SIGN in the serum did not record a significant difference between gender and age, as well as the blood groups. To determine the impact of the therapeutic status in RA patients on the DC-SIGN level, it was found that the concentration of DC-SIGN level was higher in untreated patients compared to treated patients. Regarding viral infection, when an investigation was conducted in RA patients infected with SARS-CoV-2, the serum level of DC-SIGN in RA patients with COVID-19 showed no change in concentrations compared to uninfected RA patients.
There are many characters which belong to small & medium projects, this is not relate to their size only but also to its quality charchcters & the quantities indicators.
There is a focus in the ownership, management, Resources beside the limited internal control system.
the auditor must put his program according to the project’s circumstance, so auditing the small projects differs than other projects which maybe is less complex and done by limited persons
This research aims to show the responsibility of certified public accountant in evaluation the risks of the small & medium projects through depending the audit- based risk program which develop the useful information.
كان الفساد وما زال أحد المواضيع الرئيسة التي شغلت اهتمام الباحثين والدارسين في المجالات المعرفية المختلفة بضمنها المجال الإداري نظراً للتأثير السلبي والمباشر لإدارات المؤسسات الحكومية العامة على نجاح برامج وخطط التنمية في تحقيق أهدافها المجتمعية, إذ أن عملية تنفيذ هذه البرامج تقع على عاتق إدارات هذه المؤسسات في إطار التزام العاملين فيها بتحقيق الأهداف والسياسات التنموية العامة للدولة ، وحرصهم على تلبية ا
... Show MoreThe fashion accused important optical avenge with the rest of visual elements
, That style of fashion design stir up beautiful feelings by using fashion forming
that is suitable with the nature of designable treatments to other elements .
The fashions contains the nature of relation ships of educational address and
the kind of beliefs , So the visual beauty is limited for those relation which are the
designer fashion tried to redesign and set them anew . so as to goes with beautifully
with the last visual for fashions.
Experimental investigations have been carried out to investigate the pH-control problems of industrial electroplating wastewater treatment plants. The accurate and sensitive PID control system could treat most problem and disturbances in the normal operation of the water treatment. However, conventional treatment was replaced by proprietary treatment agent called a QUASIL which was found to be more effective for a wide range of pH.
Abstract
In light of the great technological development and the emergence of globalization has increased global competition, where it became competitive exercise pressure on all sectors. In light of this companies mast enviorment depend on the means that keeps them on the competitive position through access to information about competitors in order to help them to draw a strategy that will achieve a competitive edge either through excellence or reduce the costs of their products and this means intelligence competitive and reverse engineering that help to gain information on competitors analyze and put of the decision-maker From this point formed the idea of research in the statement of the role of
... Show Moreهدف البحث إلى التعرف على اصالة الذات فضلاً عن التعرف على الفروق في اصالة الذات بين الطلبة على وفق متغير الجنس (ذكر – انثى) والتخصص الدراسي (علمي – انساني) والمرحلة الدراسية (أول- رابع)، تألفت عينة البحث من (140) طالبا وطالبة من طلبة جامعة الموصل-كلية التربية الاساسية، وتم تطبيق مقياس البحث - مقياس (اصالة الذات) وهو (من إعداد الباحثة)، وقد اسفرت نتائج البحث عن: - إن طلبة الجامعة يتمتعون بأصالة الذات. - عدم وجود فروق في
... Show Moreتُعد فكرة الذكاء الاصطناعي من العلوم الحديثة التي ارتبطت بالإنسان منذ العقود الخمسة الماضية، وأصبحت السياسة الرقمية جزءاً لا يتجزأ من المجتمع لكونها تُستخدم في أغلب مجالات حياة الانسان. وهذا ما شجع صانعوا السياسات التكنولوجية الجديدة في التفكير بكيفية توظيفها لخدمة مصالحهم العليا السياسية والعسكرية، للتعزيز من قوتهم ونفوذهم، وغاضين النظر عن بذل الجهود للتفكير في تنظيمهم للذكاء الاصطناعي التوليدي، ووضعه
... Show Moreيهدف البحث إلى قياس تاثير راس المال المودع للمستثمرين غير العراقيين والمستثمر في أسهم شركات المدرجة في سوق العراق للأوراق المالية في القيمة السوقية لتلك الشركات
The research aims to study and analyze the reality of the internal control system in the company surveyed . To find out how effective and efficient internal control system , problem – centered research that addressed the performance of the internal control system .
The research Description applied and the interview Alchksahvi analysis and interpretation of results . The researchers recommended the need for attention to the training courses and the need for segregation of duties and functions in the main and subsidiary records , taking in to account periodic reconciliations between the lists and financ
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