Vitamin D receptor (VDR) is a nuclear transcription factor that controls gene expression. Its impaired expression was found to be related to different diseases. VDR also acts as a regulator of different pathways including differentiation, inflammation, calcium and phosphate absorption, etc. but there is no sufficient knowledge about the regulation of the gene itself. Therefore, a better understanding of the genetic and epigenetic factors regulating the VDR may facilitate the improvement of strategies for the prevention and treatment of diseases associated with dysregulation of VDR. In the present investigation, a set of databases and methods were used to identify putative functional elements in the VDR locus. Histone modifications, CpG Islands, epigenetic marks at VDR locus were indicated. In addition, repeated sequences, enhancers, insulators, transcription factor binding sites and targets of the VDR gene, as well as protein-protein interactions with bioinformatics tools, were reported. Some of these genetic elements had overlapped with CpG Islands. These results revealed important new insight into the molecular mechanisms of the VDR gene regulation in human cells and tissues.
يتناول هذا البحث موضوع مهم في تاريخ العراق في العهد الملكي يتمثل في الانقلاب العسكري الذي قام به عدد من قادة الجيش العراقي بقيادة الفريق بكر صدقي رئيس أركان الجيش العراقي سنة 1936م وتم تشكيل حكومة من الانقلابيين استمرت حوالي تسعة أشهر وكتب عنها الكثير بعض هذه الكتابات كانت مع الانقلاب وبعضها كانت ضده وجاء هذا البحث ليسلط الضوء على ألصوره الذهنية التي حاولت ان ترسمها الصحف العراقية في حينها وتم دراسة الموضوعات
... Show Moreيهدف هذا البحث إلى معرفة أثر استخدام دورة التعلم في اكتساب المفاهيم الصرفية واستخلاصها لدى طالبات قسم اللغة العربية بكلية التربية للبنات وقد صيغت فرضيتان مفادهما أن ؛ 1- لا توجد فروق ذات دلالة إحصائية بين متوسط درجات طالبات المجموعة التجريبية اللاتي يدرسن المادة الصرفية في دورة التعلم ومتوسط درجات طالبات المجموعة الضابطة اللاتي يدرسن المادة الصرفية بالطريقة القياسية لاكتساب المفاهيم. 2- لا توجد فروق ذ
... Show MoreGod Almighty has prepared for this nation men who made its glory, built its glories, and elevated it to the sublime of its glory, until it was the best nation brought out to people.
Among these notables are those who served the Noble Qur’an, and sacrificed the most precious to reveal its secrets, and to defend the Noble Qur’an against atheists and skeptics, namely Imam (Zain El-Din Muhammad Ibn Abi Bakr Ibn Abd al-Qadir al-Razi, 666 AH), that venerable scholar, and the great sea, who He was known to be: an interpreter, linguistic, jurisprudent, jurisprudence on the Hanafi school of thought. Among his most prominent books are: (Mukhtar Al-Sahah) on language, (Explanation of the Haririya Maqamat) and (Hadiqat al-Ha
... Show Moreالمستخلص تهدؾ الدراسة الى ل اٌس مدى التطب كٌ والتبن للم اٌدة ال مٌظة ف المنظمات العامة ولد اشتمت مشكلة الدراسة النظر ةٌ من وجود فجوه معرف ةٌ وذلن لملة الدراسات والبحوث الت تناولت متؽ رٌ الدراسة بأبعاده )الرؤ ةٌ المح طٌ ةٌ, التمك نٌ, الشبكات ب نٌ اعضاء الفر قٌ, الترك زٌ, الم لٌ للتعامل مع حالات عدم التأكد( اعتمدت الدراسة منهج دراسة الحالة عن طر كٌ استعمال استمارة الفحص ف المنظمة الت تم اخت اٌرها دائرة العمل والتدر ب
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This research was conducted to test the hypothesis (There is no significant moderating effect for Dramaturgy on the relationship between impression management strategies and PTSD), (45) employees in Iraqi drilling company (Basra province) were selected as a sample. Findings showed that the percentage (0.91%) of the employees who are exposed to accidents as a result of work suffer from post traumatic stress disorder, which negatively affects their organizational behavior, thereby, reducing future performance, findings also showed that the employment of impression management strategies will assist management to address PTSD among employees wh
... Show Moreيهدف البحث الى قياس مدى التطبيق والتبني للقيادة الملهمة في المنظمات العامة، وقد اشتقت مشكلة البحث النظرية من وجود فجوة معرفية وذلك لقلة الدراسات والبحوث التي تناولت متغير البحث بأبعاده (الرؤية المستقبلية، الثقة بالنفس، تمكين العاملين، ادارة التغيير)، واعتمد البحث المنهج التحليلي عن طريق استعمال الاستبانة في المنظمة التي تم اختيارها وذلك لكونها تعد من المنظمات الاساسية في تقديم الخدمات التعليمية المهمة في
... Show MoreThe audit committees are considered to be one of the most important committees because of the role they play in supervising and monitoring the process of formation of the financial statements and correction of the internal supervising system also strengthening the independency of the internal and external audit. Matters which increases the efficiency and integrity of the financial statements which reflects positively on competence of board of directors and then enhance the position of the company through increasing the trust of the users of the financial statement within the company.
Therefore, this research deals with the evaluation of the performance of the audit committees in Iraqi banks according to the local rules and
... Show MoreThe Abbasid period is one of the most fertile Islamic ages attention to the bookcases have been prominent of each of the caliphs, ministers and dignitaries acquisition of books and stop in the coffers of public books, so that the largest number of students of science to see them. Baghdad's portfolio of scientific status in the late Abbasid times, which was characterized by weakness and division
Find extract This research aims to find out (after learning strategy cells in the development of critical thinking and reflective thinking at the fifth-grade students in the geographic literary material). And follow researcher Almhnj demo for the purpose of achieving the goals of current research and design on an experimental group and a control with a test group after me and adopted chose researcher sample Find a way Mqsidih students of junior high Kadhimiya Boys of the breeding Baghdad / Karkh II and to verify the effectiveness of the search coined researcher hypotheses following cases: - 1. No statistically significant between the mean scores of the experimental group and the students taught her students that strategy differences (lea
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