آمنة هيثم عبداللطيف
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Amenah H. Abdulateef
MSc
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assistant lecturer
College of Science for Women
,
Department of Biology
[email protected]
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Publication Date
Sat Dec 01 2018
Journal Name
Applied Soft Computing
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Publication Date
Mon Aug 26 2019
Heuristic Modularity for Complex Identification in Protein-Protein Interaction Networks
complex detection
graph partitioning
heuristic
modularity
Protein-Protein Interaction network
Due to the significant role in understanding cellular processes, the decomposition of Protein-Protein Interaction (PPI) networks into essential building blocks, or complexes, has received much attention for functional bioinformatics research in recent years. One of the well-known bi-clustering descriptors for identifying communities and complexes in complex networks, such as PPI networks, is modularity function. The contribution of this paper is to introduce heuristic optimization models that can collaborate with the modularity function to improve its detection ability. The definitions of the formulated heuristics are based on nodes and different levels of their neighbor properties. The modulari
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