One of the challenges faced by traditional intrusion detection systems based on machine learning or deep learning is instability when dealing with unbalanced network traffic, leading to failure in detecting certain attacks (minority classifications). Additionally, they struggle with multi-stage attacks, resulting in an increase in false alarms. This paper presents a hierarchical intrusion detection system supported by a Prediction Verification Layer (PVL) and a Feature Inheritance Mechanism (FIM). Where PVL contributes to documenting the system’s final decision and increasing sensitivity to minority attacks, FIM also helps in inheriting features from previous layers and correcting errors as much as possible. Additionally, it allows for ad

Community detection is one of the most fundamental applications in understanding the structure of complicated networks. Furthermore, it is an important approach to identifying closely linked clusters of nodes that may represent underlying patterns and relationships. Networking structures are highly sensitive in social networks, requiring advanced techniques to accurately identify the structure of these communities.Most conventional algorithms for detecting communities perform inadequately with complicated networks. In addition, they miss out on accurately identifying clusters. Since single-objective optimization cannot always generate accurate and comprehensive results, as multi-objective optimization can.Therefore,we utilized two objective

Recently, detecting dynamic patterns for growing communities in social networks have attracted significant attention. The objective of dynamic community detection is to analyze and identify clusters in complex networks that change over time. Different optimization algorithms, including both single-objective and multi-objective approaches, have been employed to address the challenge of dynamic community detection. Although current evolutionary algorithms for identifying community structure can traverse extensive areas of partition space, they often become stuck in local minima. In addition, limited studies have addressed this issue by integrating local search strategies with evolutionary algorithms for community identification. This paper in

EGFR-mutant non–small cell lung cancer (NSCLC) initially responds well to EGFR tyrosine kinase inhibitors (EGFR-TKIs), yet resistance is nearly inevitable and responses to immune checkpoint inhibitors (ICIs) remain limited. In a retrospective cohort of 57 patients with advanced EGFR-mutant NSCLC treated with nivolumab or pembrolizumab, the objective response rate was 12.3%, although responses were concentrated in a small subgroup with concurrent high PD-L1 expression and dense intratumoral CD8⁺ immune-cell infiltration. Emerging evidence links these outcomes to chemokine-network dysregulation that alters immune trafficking and spatial organization. Oncogenic EGFR signaling shifts chemokine networks away from effector T-cell recruitment

The use of sugarcane molasses (SCM) as a sustainable stabilizing agent for geomaterials, particularly granular subbase soils, has recently attracted growing attention as an alternative to traditional stabilization methods employing cement, lime, or bitumen, which are often associated with high costs and environmental concerns. This study presents a mechanistic–experimental evaluation of SCM for stabilizing granular subbase materials at dosages of 2.5%, 5%, 7.5%, and 10% by weight of dry granular material. A comprehensive testing program was conducted, including compaction characteristics, California Bearing Ratio (CBR), resilient modulus (Mr), permanent deformation under repeated loading, optical microscopy, and FTIR spectroscopy.

Abstract This study examines the patterns of women's participation in foreign policymaking and analyzes the extent to which their integration into diplomatic institutions contributes to strengthening the effectiveness of foreign policy decision-making. It focuses on the institutional and administrative frameworks that have facilitated women's access to diplomatic leadership positions and decision-making processes within ministries of foreign affairs and other foreign policy institutions.The study assumes that the effectiveness of women's participation is determined not merely by their numerical representation but by the extent to which such participation is supported by institutional reforms founded on merit, transparency, and professional

Phthalates are ubiquitous environmental contaminants widely used as plasticizers in poly vinyl chloride products, and growing evidence implicates them in metabolic activity reduction and epigenetic dysregulation. However, their direct effects on non-transformed human cells remain incompletely characterized. The present in vitro study evaluated the reduction in cell viability and DNA methylation–modulating effects of three widely distributed phthalates, di(2-ethylhexyl) phthalate (DEHP), di-n-butyl phthalate (DnBP), and di-isononyl phthalate (DINP), on normal human fibroblast (NHF) cells. Cells were exposed to serial concentrations (31.25–1000 μg/mL) for 72 h, and the viability was assessed by MTT assay, followed by IC50 determinati

Background: Fluoropyrimidines are widely used in the treatment of various solid tumors. One-third of cancer patients develop severe treatment-related toxicity. A part of fluoropyrimidine-related toxicity arises due to impaired activity of dihydropyrimidine dehydrogenase (DPD) caused by genetic variants in the DPYD gene. Objective: This study aims to determine the frequency of DPYD mutations among patients with adverse effects of 5-fluorouracil therapy. Materials and Methods: This cross-sectional study recruited 46 patients with 5-FU adverse effects. All demographic, clinical, and laboratory findings were recorded. Molecular testing was conducted to detect the DPYD mutation using the PGX-5FU StripAssay® kit, which identifies the IVS14 + 1G>

Electric vehicles are emerging as a sustainable alternative to conventional transportation. However, route planning in Internet of Vehicles environments remains challenging because conventional routing algorithms based on travel distance or time do not adequately consider electric vehicle-specific constraints. Existing routing strategies often overlook the combined effects of battery energy, traffic congestion, and charging requirements, resulting in inefficient routing decisions. This paper proposes an adaptive Energy, Congestion, and Charging-Aware Routing (ECCAR) protocol that uses energy-feasibility verification, cost-based charging-station selection, and route re-optimization for electric vehicles in Internet of Vehicles enviro

Purpose: Current denture liner materials suffer from low tear strength, poor abrasion resistance, weak bond strength to denture material, and increasing risk of denture stomatitis due to adherence. The aim of this study was to evaluate the effects of the addition of cellulose nanofibers (CNFs) to commercial soft denture liner material on the adherence of and physical and mechanical properties. Materials and Methods: CNFs at concentrations of 0.0, 0.5, and 1.0 wt.% were incorporated into a soft liner material. Antifungal effects were assessed by quantifying the adherence of . The Shore A hardness, tensile strength, peel bond strength, and surface roughness tests were employed to assess the properties of the denture liner materials. Chemica

The gastrointestinal system is one of the many organs in the body that have been affected by the new viral illness known as coronavirus disease 2019 (COVID-19). To find out the GIT symptoms are into patients with Covid-19 and how they correspond with the severity of the illness. At the Al-Shifaa facility, 172 patients infected with COVID-19 participated in our study. A clinical examination, laboratory tests (CRP, D.Dimer, and serum ferritin), a chest CT scan, and a medical history were performed on each patient. The severity of the illness and other factors were taken into consideration while evaluating the gastrointestinal symptoms. Data collection from 172 patients, 91 patients infected with COVID-19 infection, 91 patients (52.9%) had GIT

بعد دخول تنظيم داعش إلى مناطق غرب وشمال العراق وتمدد التنظيم جاءت فتوى المرجعية الدينية التي ثبتت ظهور الحشد الشعبي الذي صار أهم اذرع المؤسسة العسكرية والأمنية في العراق وبعد تعافي الأجهزة الأمنية نتيجة الدعم الجماهيري والشعبي من خلال وجود الحشد الشعبي كقوة داعمة ومكملة للأجهزة الأمنية تم تحرير كافة المناطق التي سيطر عليها تنظيم داعش الإرهابي .  الكلمات المفتاحية: (الحشد الشعبي، المرجعية الدينية، تنظي

Background: Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder affecting women of reproductive age. Oxidative stress may contribute to its pathogenesis. Paraoxonase-1 (PON1) is an antioxidant enzyme associated with high-density lipoprotein, and its genetic polymorphisms may alter enzyme activity. This study aimed to investigate the association between PON1 L55M polymorphism (rs854560) and PCOS in Iraqi women.Methods: This case-control study included 80 women aged 20–35 years who were in good general health   and matched for age and body mass index (BMI). Genomic DNA was extracted using a commercial kit. The PON1 L55M polymorphism was amplified by polymerase chain reaction and genotyped by direct sequen

his research aims to identify fear of missing out on opportunities among university students in terms of gender and specialization (scientific and humanities). To achieve this objective, the researchers adopted the fear of missing out on opportunities scale developed by Subhi Hamid and Issa Al-Daghistani(2023). The scale, in its final form, consisted of 10 items. The researchers confirmed the psychometric properties of the scale. Then, it was administered to 140 male and female students selected using stratified random sampling from four colleges at the University of Baghdad (College of Arts, College of Education, College of Engineering, and College of Science) during the 2024-2025 academic year

Sustainable development has recently gained significant attention in the field of water Quality (WQ), which is critical for a healthy lifestyle. Our work suggests an intelligent hybrid model for assessing water quality using a water portability dataset, which was used to evaluate the water quality. The dataset contains physical and chemical features such as pH, Organic Carbon, sulfate, etc. Based on the combination of a Decision Tree Algorithm (DTA) and fuzzy logic Approaches, the findings revealed that sulfate was the most important factor in the model, with an accuracy of 1.00, followed by pH with an accuracy of 0.9667, and solids and chloramines with an accuracy of 0.95. The other parameters achieved a similar accuracy of 0.9167, showing

تحظى دراسة الصحف أو مواقفها من الأحداث التاريخية باهتمام كبير من قبل الباحثين في مجال التاريخ الحديث لكونها أحدى المصادر التي لا يمكن الاستغناء عنها ، وذلك لمرافقتها الأحداث السياسية والاقتصادية والاجتماعية بشكل يومي فهي تعمل على جمع المعلومات بشكل دقيق وتحليل محتواها ومتابعة كل المستجدات حول الأخبار المنشورة فيها ، ولقد كان للصحافة اللبنانية ولاسيما صحيفة الأنوار دوراً كبيراً في جمع ونقل والتفاعل مع

   هدف البحث الى دراسة التعديلات الدستورية للحقوق المدنية في الولايات المتحدة الامريكية وتحليلها، منذ اصدار دستور الولايات المتحدة 17 ايلول 1787؛ وبداية اولى التعديلات الدستورية في مرحلة الاعمار أي ما بعد الحرب الاهلية الامريكية، وصدور التعديل الخاص بحقوق التصويت للمواطنين الامريكيين، فضلا عن التعديلين الرابع عشر والخامس عشر ، والتي اسهمت في تأطير الحقوق المدنية بشكل رسمي وقانوني ، لكن تطبيقها تطلب الم

Objective: This paper attempts to shed light on the despoilment of membership of Egyptian Parliament members during 1976-1979 and be a run down to how does revocation against them had comprehended provisions of 1971 Egypt constitution. ‎ Method: This is a historical-analytical design to study reasons provided on the Membership Revocation for Members of the Egyptian People's Assembly, which comes because of the loss of credibility, and not performing the ‎obligations of the membership. Study data ‎were sourced from legislative documents and legal documents. This was followed by detailed case studies of Kamal ‎El-Din Hussein, Sheikh Ashour Mohamed Nasr, and Abdel Fattah Hassan. Results: There was a political motive behind thes

يتناول هذا البحث موقف ( صحيفة الاهرام) المصرية من تطورات الصراع في جمهورية الكونغو الديمقراطية خلال الفترة (1964 -1965) وهي مرحلة اتسمت باحتدام الازمات السياسية والنزاعات الداخلية في الكونغو مع زيادة التدخل الاجنبي في شؤون البلاد المتمثل بالولايات المتحدة الامريكية وبلجيكا وعلى هذا الاساس تم اختيار موضوع البحث والذي حددت بدايته بالتزامن مع عودة مويس تشومبي الى السلطة ، وما رافقها من صراعات وتمردات في الاقاليم

A superb demonstration of one of the wonders of technology providing the people with great aid is the employment of Artificial Intelligence in the medical field, and mainly the introduction of Clinical Decision Support Systems (CDSS). Nevertheless, non-’black-box’ AI systems have a significant problem, that is, although they are visible and understandable, there is still a considerable issue of trust by healthcare professionals. Explainable AI (XAI) technology is a means to overcome all the obstacles by unveiling more and offering the explanations of the procedures that AI performs in decision making. This study was conducted by examining various widely used approaches to XAI, which illustrate how XAI verifies the trustworthiness of CDS

The growing emphasis on sustainable construction has prompted interest in repurposing agricultural by-products as alternatives to conventional aggregates in asphalt mixtures. While natural sand is widely available, its use can lead to less stable, more tender mixes, which can limit various specifications. This study explores the potential of palm date seed (PDS) powder as a partial and full replacement for natural sand in asphalt concrete. A series of laboratory tests was conducted to evaluate the effect of PDS incorporation on the mechanical and durability performance of asphalt mixtures, including Marshall properties, resilient modulus, fatigue resistance, moisture susceptibility, and permanent deformation. Additionally, microstructural a

Background : Ebastine (EBS) is an antihistamine medication commonly used to alleviate symptoms associated with allergic rhinitis and pruritic skin conditions, such as urticaria and other pruritic dermatoses. The main advantage of oral lyophilisates is their high porosity, which facilitates rapid salivary penetration, short disintegration times, and improved bioavailability.

Method : EBS-loaded Solusome nanovesicles were formulated via the thin-film hydration technique using Soluplus® as a stabilizing agent within the nanovesicle system. The Solusome nan

A numerical investigation was performed on triangular solar air collectors by integrating unique layouts of triangular and alternating triangular copper metal foams with graded and non-graded pore densities. A three-dimensional CFD model was established to solve the governing equations of coupled systems for porous and non-porous domains. The two-energy-equations model was implemented to simulate heat transfer in porous media. The mathematical model was validated with numerical and experimental tests, with maximum mean absolute percentage error of 5% and 7%, respectively. To compromise heat transfer improvement with pressure losses, a partial metal foam insertion was adopted, covering 10% to 25% of the air duct volume. The findings indicate