Preferred Language
Articles
/
zBfxeo0BVTCNdQwCCBWg
Gut dysbiosis and immunological profile in endometriosis
...Show More Authors
Abstract<p>Ectopic growth of normal cells or debris originating from endometrium, the inner layer of female reproductive tube leads to endometriosis. The main symptoms are dyspareunia, dysmenorrhea, and sometimes chronic pelvic pain. Unfortunately, it has no cure or treatment, only symptoms relief medication or surgical removal. Endometriosis causes estrogen imbalance leading to intestinal bacterial estrobolome dysregulation and subsequent change in immune response. Our study aims to investigate the linkage between gut dysbiosis and immunological response in endometriotic mice. Balb/c mice were ovariectomized (OVX) 7 days before intraperitoneal transplantation of 2mm2 endometrial tissue from OVX donors to OVX- or intact ovary recipients. Colonic content was collected 2 weeks post transplantation for 16s rRNA pyrosequencing. Peritoneal exudate was collected and stained to determine the phenotype of infiltrating cells by flow cytometry. Results revealed a significant increase in the number of exudate cells, natural killer (NK) cells and myeloid derived suppressor cells (MDSCs) in endometriotic mice. Phylogenetic taxonomy showed an increase in the biomass of the bacteria in endometriotic OVX mice in comparison with endometriotic nonovariectomized mice. However, the abundance of Phylum Tenericutes, Order Clostridiales, Dehalobacterium sp. and Anaeroplasma sp. were decreased. Collectively, endometriosis changed estrogen metabolism and gut microbiota which resulted in the immune modulation. (Supported by NIH P01AT003961, R01AT006888, R01MH094755, P20GM103641, R01AI129788 and R01AI123947 to PN and MN, and MoHESR to AKM).</p>
Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Fri Nov 01 2019
Journal Name
Journal Of Physics: Conference Series
The Bifurcation analysis of Prey-Predator Model in The Presence of Stage Structured with Harvesting and Toxicity
...Show More Authors
Abstract<p>For a mathematical model the local bifurcation like pitchfork, transcritical and saddle node occurrence condition is defined in this paper. With the existing of toxicity and harvesting in predator and prey it consist of stage-structured. Near the positive equilibrium point of mathematical model on the Hopf bifurcation with particular emphasis it established. Near the equilibrium point E<sub>0</sub> the transcritical bifurcation occurs it is described with analysis. And it shown that at equilibrium points E<sub>1</sub> and E<sub>2</sub> happened the occurrence of saddle-node bifurcation. At each point the pitch fork bifurcation occurrence is not happened. </p> ... Show More
View Publication
Crossref (1)
Crossref
Publication Date
Sat Sep 30 2023
Journal Name
Iraqi Journal Of Science
Investigating the Antioxidant and Apoptosis Inducing Effects of Biologically Synthesized Silver Nanoparticles Against Lymphoma Cells in Vitro
...Show More Authors

     The current study aimed to synthesize silver nanoparticles (Ag NPs) in a safe and eco-friendly biological method using green tea extract, characterize them using UV-vis spectroscopy, FTIR, XRD, FESEM, and AFM tools, then investigate their antioxidant potentials against DPPH and their cytotoxicity toward lymphoma cells using MTT and ethidium bromide/propidium iodide dual staining assays, and their genotoxic capacities by assessing their effects on the gene expression of p53, caspase3, bcl-2, and bax genes by qPCR and DNA fragmentation.  Results confirmed the synthesis of silver nanoparticles; the UV-vis results showed a peak of absorbance at 414 nm; FTIR analysis showed absorbance bel

... Show More
View Publication Preview PDF
Scopus Crossref
Publication Date
Mon Dec 01 2014
Journal Name
Iraqi Journal Of Science,
Detection of human leukocyte antigen and celiac disease auto antibodies in serum of patients with multiple sclerosis
...Show More Authors

To determine the important pathogenic role of celiac disease in triggering several autoimmune disease, thirty patients with Multiple Sclerosis of ages (22-55) years have been investigated and compared with 25 healthy individuals. All the studied groups were carried out to measure anti-tissue transglutaminase antibodies IgA IgG by ELISA test, anti-reticulin antibodies IgA and IgG, and anti-endomysial antibodies IgA and IgG by IFAT. There was a significant elevation in the concentration of anti-tissue transglutaminase antibodies IgA and IgG compared to control groups (P≤0.05), there was 4(13.33%) positive results for anti-reticulin antibodies IgA and IgG , 3(10%) positive results for anti-endomysial antibodies IgA and IgG . There were 4 pos

... Show More
Publication Date
Thu Jun 01 2023
Journal Name
Baghdad Science Journal
Simultaneous Determination of Piroxicam and Codeine Phosphate Hemihydrate in a Pharmaceutical Dosage Form Using Validated HPLC Method
...Show More Authors

An easy, eclectic, precise high-Performance Liquid Chromatographic (HPLC) procedure was evolved and validated to estimate of Piroxicam and Codeine phosphate. Chromatographic demarcation was accomplished on a C18 column [Use BDS Hypersil C18, 5μ, 150 x 4.6 mm] using a mobile phase of methanol: phosphate buffer (60:40, v/v, pH=2.3), the flow rate was 1.1 mL/min, UV detection was at 214 nm. System Suitability tests (SSTs) are typically performed to assess the suitability and effectiveness of the entire chromatography system. The retention time for Piroxicam was found to be 3.95 minutes and 1.46 minutes for Codeine phosphate. The evolved method has been validated through precision, limit of quantitation, specificity,

... Show More
View Publication Preview PDF
Scopus Crossref
Publication Date
Sat Sep 30 2023
Journal Name
Journal Of Accounting And Financial Studies ( Jafs )
The effect of changing interest rates on net interest income and earnings per share in commercial banks
...Show More Authors

ABSTRACT:

              Interest rates are one of the important aspects that affect the banking business directly, which is characterized by unstable dynamic dynamics, which must be viewed on a daily and continuous basis through the macroeconomic view, which directly affects the bank’s income realized from loans as interest received or interest paid on its deposits as an expense. Hence the earnings per share. The relationship between interest rates and between net income and earnings per share was measured and a correlation was found between them, and then the effect between them was measured using regression equations and they were applied and th

... Show More
View Publication Preview PDF
Publication Date
Sun Jan 01 2017
Journal Name
Proceeding Of Second Thermal And Fluids Engineering Conference
Solidification Enhancement in Triplex-Tube Latent Thermal Energy Storage System Using a Combination of Nanoparticles and Fins
...Show More Authors

View Publication
Crossref (1)
Crossref
Publication Date
Tue Feb 25 2025
Journal Name
Journal Of Engineering
Parametric Study Of Laminar Free Convection In Horizontal Annulus With And Without Fins On The Inner Cylinder
...Show More Authors

View Publication
Publication Date
Sun Dec 01 2019
Journal Name
Journal Of Engineering Science And Technology (jestec)
Water Quality Assessment And Total Dissolved Solids Prediction For Tigris River In Baghdad City Using Mathematical Models
...Show More Authors

Total dissolved solids are at the top of the parameters list of water quality that requires investigations for planning and management, especially for irrigation and drinking purposes. If the quality of water is sufficiently predictable, then appropriate management is possible. In the current study, Multiple Linear Regression (MLR) and Artificial Neural Network (ANN) models were used as indicators of water quality and for the prediction of Total Dissolved Solids (TDS) along the Tigris River, in Baghdad city. To build these models five water parameters were selected from the intakes of four water treatment plants on the Tigris River, for the period between 2013 and 2017. The selected water parameters were Total Dissolved Solids (TDS

... Show More
Publication Date
Tue Aug 01 2017
Journal Name
Journal Of Engineering
Rigid trunk sewer deterioration prediction models using multiple discriminant and neural network models in Baghdad city, Iraq
...Show More Authors

The deterioration of buried sewers during their lifetime can be affected by several factors leading to bad performance and can damage the infrastructure similar to other engineering structures. The Hydraulic deterioration of the buried sewers caused by sewer blockages while the structural deterioration caused by sewer collapses due to sewer specifications and the surrounding soil characteristics and the groundwater level. The main objective of this research is to develop deterioration models, which are used to predict changes in sewer condition that can provide assessment tools for determining the serviceability of sewer networks in Baghdad city. Two deterioration models were developed and tested using statistical software SPSS, the

... Show More
Publication Date
Thu Mar 01 2018
Journal Name
Journal Of Baghdad College Of Dentistry
Waterpipe Smoking Effect on Clinical Periodontal Parameters, Salivary Flow Rate and Salivary pH in Chronic‎ Periodontitis Patient
...Show More Authors