The study aimed to compare the expression of miR-126-3p and miR-423-5p in patients and normal subjects, and correlate their expression with response to induction therapy. Circulating miR-126-3p and miR-423-5p were measured in the plasma of 43 adult AML patients and 35 age- and sex-matched controls by real time PCR. The foldchange in differential expression for each gene was calculated using the comparative cycle threshold (CT) method (also known as the 2−CT method). For statistical purposes, the fold change was calculated using DDCT (or 2–∆∆Ct) method to find the relative expression of miRNAs. The expression fold change of miR-126-3p was 1.73-fold increase in patients than controls (p= 0.010). The expression fold change of miR-423-5

Abstract Background: Acute myeloid leukemia (AML) results from sequential genetic alterations in a normal hematopoietic stem cell or its progenitors giving rise to an autonomous clone that dominates the bone marrow leading to marrow failure. MicroRNAs are short non-coding nucleic acid sequences that regulate post-transcriptional gene expression by base-pairing with their target mRNAs. MiRNAs can be secreted into extracellular fluids and carried to target cells by vesicles or bound to proteins. Intracellular and circulating miRNAs are believed to be useful markers in the diagnosis, prognosis, and treatment of various cancers. Practically, circulating miRNAs are more stable at room temperatures and extreme conditions. Purpose: This study aim

Achieving the Book of Return to the End of the Book of Alimony from the Manuscript of the Forum of the Abhar of the Sheikh (Abraham Bin
Muhammad ibn Ibrahim al-Halabi (d. 956 AH), who was a member of the Hanafi sect, was a long man
Fiqh, interpretation, modernity, Arab sciences, and readings
Hanafi as well as that he was Abid Zahid and the reason for his claim to this book that asked him some
He asked him to take advantage of it
Al-Hanafiya said, mentioning the sources from which he was taken, and presented his opinion and evidence on the correct
He mentioned the issues of the Hanafi jurisprudence in his book according to the chapters of the jurisprudence
Reaction is done to what you have achieved previously in the h

Goal  of  research  is  to  investigate  the  impact  of the  use  of  effective  learning  model in the  collection  of  the  fourth  grade  students/Department of  physics in the material  educational methods  and the  development  of  critical thinking  .to teach  this goal  has  been  formulated  hypothesis cefereeten zero  subsidiary  of the second hypothesis  .To  investigate  the  research  hypothesis  were  selected  sample  of  fourth-grade  students of the  department  of physics at the univers

This research deals with the rhetoric purposes of the passive voice in the holy Quran. First, we put an introductory to the concept of the Quran language and its difference of the spoken Arabic language during the revelation period. Besides; we gave a brief about the structure passive voice form of Arabic language. Second, we explained the purposes of passive voice used in the holly Quran with sufficient examples, commentaries and clarifications about all the cases. Rhetoric purposes that we deals with are: concision, emphasize an idea, avoid using the subject because it is known and clear for all or because it is really unknown, etc. This part has contained the most important purposes for the use of passive voice in holy Quran. At the end

All alive languages had passed linguistic changes that made the mother language not recognized by its present speakers. Some of these changes are: syntactical, semantical, orthographical, phonetical and lexical.During the period of changes which extends over centuries, there had been a lof of written texts, such as literately texts, biographies, personal memories and manuscripts which are conserved until now as a literatel, historic and linguistic testimonies.Spanish is one of these languages that had been changed, so, the poem of the Cid (1145) was written in a Spanish which differs from the Spanish in which Cervantes wrote the Don Quixote in (1605/1615) and the Spanish of both of them differs from the Spanish of Francisco Ayala and Azorin

El moviemiento literario español de posguerra ha visto un cambio muy transcendental al nivel de plantear los temas y la  técnica de formar el genero literario ,de forma que la poesίa ha ocupado un espacio muy significativo en ello ,dado que los poetas buscaban metedos creativos para atraer el público , siguiendo senedores que pudieran afectar de forma u otra en las mentes y sentimientos.

        En esta dirección ,Gabriel Celaya se resalta como voz que ha  traspasado el ánimo de dos promociones genericas que son la de 27 y la de 36, por lo cual podίa conllevar unas asencias muy basicas de la poesίa española que envuelven la precisión clásica y prodencia contemporanea, con

Los enunciados interrogativos desempeñan un papel de sumo interés en el habla del ser humano en todo el mundo, además de la gran importancia que desempeñan sus distintos enunciados y partículas en abreviar las oraciones y hacer llegar a nuestro interlocutor nuestra intención con pocas palabras, por eso a través de esta investigación vamos a enfocar la luz sobre uno de sus tipos fundamentales "los enunciados interrogativos directos", a través de un estudio morfológico contrastivo entre el árabe y el español, este fue el principal motivo para elegir este tema.
A pesar de que los enunciados interrogativos directos aparentemente no ofrecen mucha dificultad, pero dominar a dicho tipo de enunciados con todas sus divisiones, sus

_{Los enunciados interrogativos desempeñan un papel de sumo interés en el habla del ser humano en todo el mundo, además de la gran importancia que desempeñan sus distintos enunciados y partículas en abreviar las oraciones y hacer llegar a nuestro interlocutor nuestra intención con pocas palabras, por eso a través de esta investigación vamos a enfocar la luz sobre uno de sus tipos fundamentales "los enunciados interrogativos directos", a través de un estudio morfológico contrastivo entre el árabe y el español,  este fue el principal motivo para elegir este tema.}

_{A pesar de que los enunciados interrogativos directos aparentemente no ofrecen mucha dificultad, pero dominar a dicho tipo de enunciados con}