Amorphization of drug has been considered as an attractive approach in improving drug solubility and bioavailability. Unlike their crystalline counterparts, amorphous materials lack the long-range order of molecular packing and present the highest energy state of a solid material. Co-amorphous systems (CAM) are an innovative formulation technique by where the amorphous drugs are stabilized via powerful intermolecular interactions by means of a low molecular co-former.

This review highlights the different approaches in the preparation of co-amorphous drug delivery system, the proper selection of the co-formers. In addition, the recent advances in characterization, Industrial scale and formulation will be discussed.

Extracting moving object from video sequence is one of the most important steps
in the video-based analysis. Background subtraction is the most commonly used
moving object detection methods in video, in which the extracted object will be
feed to a higher-level process ( i.e. object localization, object tracking ).
The main requirement of background subtraction method is to construct a
stationary background model and then to compare every new coming frame with it
in order to detect the moving object.
Relied on the supposition that the background occurs with the higher appearance
frequency, a proposed background reconstruction algorithm has been presented
based on pixel intensity classification ( PIC ) approach.

Achieving energy-efficient Wireless Sensor Network (WSN) that monitors all targets at
all times is an essential challenge facing many large-scale surveillance applications.Singleobjective
set cover problem (SCP) is a well-known NP-hard optimization problem used to
set a minimum set of active sensors that efficiently cover all the targeted area. Realizing
that designing energy-efficient WSN and providing reliable coverage are in conflict with
each other, a multi-objective optimization tool is a strong choice for providing a set of
approximate Pareto optimal solutions (i.e., Pareto Front) that come up with tradeoff
between these two objectives. Thus, in the context of WSNs design problem, our main
contribution is to

Calculating the Inverse Kinematic (IK) equations is a complex problem due to the nonlinearity of these equations. Choosing the end effector orientation affects the reach of the target location. The Forward Kinematics (FK) of Humanoid Robotic Legs (HRL) is determined by using DenavitHartenberg (DH) method. The HRL has two legs with five Degrees of Freedom (DoF) each. The paper proposes using a Particle Swarm Optimization (PSO) algorithm to optimize the best orientation angle of the end effector of HRL. The selected orientation angle is used to solve the IK equations to reach the target location with minimum error. The performance of the proposed method is measured by six scenarios with different simulated positions of the legs. The proposed

Abstract:

                 The research aims to clarify the impact of adopting the IFRS16 financial reporting standard on lease contracts in insurance companies on audit procedures. The change in the classification of lease contracts in the case of adopting the IFRS16 financial reporting standard necessarily requires audit procedures that are compatible with this change. A proposed audit program was prepared, guided by international auditing standards, based on the study of the client's environment and analysis of external and internal risks in the light of financial and non-financial indicators. The researchers reached a set of concl

General medical fields and computer science usually conjugate together to produce impressive results in both fields using applications, programs and algorithms provided by Data mining field. The present research's title contains the term hygiene which may be described as the principle of maintaining cleanliness of the external body. Whilst the environmental hygienic hazards can present themselves in various media shapes e.g. air, water, soil…etc. The influence they can exert on our health is very complex and may be modulated by our genetic makeup, psychological factors and by our perceptions of the risks that they present. Our main concern in this research is not to improve general health, rather than to propose a data mining approach

It  can be said that the Security of water  in  Basra from the visual task vital strategic issues of concern to the attention of researchers in various attributions and those interested in water, environmental, economic, social, cultural and political affairs ... etc. This view of the great importance of the issue of water in the occupied Basra, which is characterized by parochialism and scarcity, When looking at the sources of our daily lives and in our reality today. We find that millions of people living on the two main exporters Tabaaan oil and water. And depleted oil wealth However Manfred him the most attention because we entered it surpasses all other sources of income, but is not it a littl

PMMA/TiO2 homogeneous thin films were deposited by using plasma jet system under normal atmospheric pressure and room temperature. PMMA/TiO2 nanocomposite thin film synthesized by plasma polymerization. Titanium oxide was mixed with Methyl Methacrylate Monomer (MMA) with specific weight ratios (1, 3 and 5 grams of TiO2 per 100 ml of MMA). Optical properties of PMMA/TiO2 nanocomposite thin films were characterized by UV-Visible absorption spectra using a double beam UV-Vis-NIR Spectrophotometer. The thin films surface morphological analysis is carried out by employing SEM. The structure analysis are achieved by X-ray diffraction. UV-Visible absorption spectra shows that the increasing the concentration of titanium oxide added to the polym

Background: targeted cancer nanotherapy represents a golden goal for nanobiotechnology to overcome the severe side effects of conventional chemotherapy. Hybrid nanoliposomes (HLs) composed of L-α-dimyristoylphosphatidylcholine (DMPC) and Polyoxyethylene (23) dodecyl ether (C12 (EO)23 ) can integrate selectively into the cancer cell membrane inducing cancer cell death.
Objectives: to assess the capacity of locally (in hose) synthesized hybrid nanoliposome to inhibit the growth of cervix cancer cells (HeLa) and induce apoptosis.
Patients and Methods: hybrid nanoliposomes(nHLs) synthesized by sonication method from a mixture of 90% mol DMPC and 10% mol C12(EO)23 in tissue culture media RPMI-1640 for 6 hours at 300W and 40ºC then fil