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Serological markers “CEA test & sAPRIL test” in Iraqi patients with colon cancer

Background: Colonic cancer is a very common disease world-wide being fourth most common cancer characterized by abnormal proliferation of the inner wall of colon then taking full colon wall thickness then spreading to surrounding lymph nodes and tissues and finally distant metastasis. It is one of most complicated diseases with debilitating symptoms which becomes more sever , prominent and specific with advancing stage with high percent of fatality and relatively short survival if diagnosed late or if left untreated.
Objective: To evaluate the efficacy of serum CEA & sAPRIL levels in the diagnosis and screening of colon cancer and their validity for this.
Patients and methods: This study was applied on 35 patients with colonic cancer, 35 patients with benign polyps and 15 negative controls. All individuals were subjected to blood sampling for measuring their serum CEA & sAPRIL using ELISA technique.
Results: In this study, majority of patients with colon cancer were presented at ages between 53-82 years of age (mean 68.5±6.4 years). Serum levels of sAPRIL & CEA were significantly elevated in those patients with advancing stages (C & D) compared with stages (A & B) and lower levels were found in patients who had surgical removal of tumor or received chemotherapy. Also a positive relation was found between sAPRIL & CEA with alcohol intake and smoking
Conclusion: according to this study sample it was found that sAPRIL and CEA together are strong indicators for colon cancer screening & diagnosis, and by this will reduce the need for more invasive screening & diagnostic tools.

 

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Publication Date
Tue Sep 20 2022
Journal Name
Journal Of The College Of Basic Education
Building challenge test for basic skills in soccer for students -third stage

The skill scale in most of sport activity monitoring a lot of dynamic behaviours conducted with playing situations that help the excerpt's in sport field to evaluate and put right solutions ,soccer one of games that studies in third stage in college and take skills ,dribbling , passing, shooting these skills helps to execute the plans in game ,the researchers notice that there is no test measure the skills of the game in the beginning of the first semester especially in the method of soccer in physical education college and the problem of the research were by answering the question that is there test connect between one or more that one of skill to measure the ability of students to execute the plans in soccer and the conclusion was the bui

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Publication Date
Fri Jul 28 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Evaluation of Dot. ELISA test for Diagnosis Visceral Leishmaniasis in Infected Children

  For the first time in Iraq, this study was conducted to evaluate the usefulness of Dot.ELISA, for detecting anti - Leishmania donovani antibodies in serum samples from suspected patient  (children under 8 years ) with Visceral Leishmaniasis V.L..  Sera from 73 V.L. , 60 Healthy controls, and 57   patient with other parasitic diseases other than V.L. (Amoebiasis, Giardiasis , Toxoplasmosis, Schistosomiasis , Hydatidosis, Ascariasis , Lupus Erythromatosus , Viral Hepatitis, and Cutaneous Leishmaniasis) were examined. Anti Leishmania donovani antibodies detected  in 71 out of 73  suspected Visceral Leishmaniasis . Data of this study showed that infection in male group was more than female group. Result o

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Publication Date
Wed Jul 01 2015
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Treatment of Forty Adult Patients with Hodgkin Disease; Baghdad Teaching Hospital Experience

Background: Hodgkin disease was the first cancer in which the curative potential of combination chemotherapy was demonstrated. The affected patients are often young and there is a great potential for adding years of productive life by giving curative therapy even when the disease is advanced.
Objective: to describe the experience of the hematology unit,Baghdad Teaching Hospital, in the management of 40 adult patients with Hodgkin disease.
Patients and Methods: a retrospective cohort study of forty adult Iraqi patients with Hodgkin disease between 2005 and 2013 in the hematology unit. Patients were treated initially with 6-8 cycles of ABVD chemotherapy protocol (doxorubicine+ bleomycin+ vinblastin+ dacarbazine) , nine patients recei

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Publication Date
Thu Apr 27 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
The Mann-Kendall Test for Temperature Trends in Some Selected Stations in Iraq

   In this paper, Mann-Kendall test was used to investigate the existence of possible deterministic and stochastic climatic trends in (Baghdad,Basrah,Mosul,Al-Qaim) stations. The statistical test was applied to annual monthly mean of temperatures for the period (19932009). The values of S-statistic were (62, 44, 52, 64) by comparing these values with the table of null probability values for S we get a probability of (0.002, 0.026, 0.010, 0.002) this result is less than α for the 95% confidence level (α = 0.05) indicating a significant result at this level of confidence. Concluded that an increasing trend in concentration is present at the 95% confidence level and the variance of the S-statistic is calculated and it is com

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Publication Date
Tue Feb 28 2023
Journal Name
Iraqi Journal Of Science
Evaluation of Plasma-microRNA320 level among Colorectal Cancer Iraqi Patients

Colorectal cancer (CRC) Patients showed different expression patterns of miRNAs which are involved in carcinogenesis in comparison to healthy controls individuals, miRNAs are involved in tumor progression and development of metastases. We investigate the expression profile of microRNA 320 and to quantify the expression level abundance among colorectal cancer patients in comparison to the healthy control group. The A total number of 60 plasma samples was collected from CRC patients along with 40 plasma samples from healthy controls and subjected to relative quantification using qPCR assay with a specified set of primers designed using s

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Publication Date
Fri Oct 01 2010
Journal Name
2010 Ieee Symposium On Industrial Electronics And Applications (isiea)
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Publication Date
Sun Jan 02 2011
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Evaluation of Rapid Chromatographic Immunoassay with Latex Agglutination Test and (ELISA) for Diagnosis of Human Toxoplasmosis

Background: there are different procedures for the diagnosis of females suspected with toxoplasmosis. However, time, cost, and accuracy of the test should meet patient’s needs.
Material and methods: one hundred and eleven female with suspected toxoplasmosis were under go three different procedures for the diagnosis of Toxoplasma gondii infection. Latex agglutination test, rapid chromatographic (immunoblot) and ELISA test were done for all patients. The results were described as frequency and percentage of positivity; also, specificity and sensitivity of immunoblot were assessed according to the result of other tests.
Results: The Latex test has shown 80% and 61.54% sensitivity and specificity respectively

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Publication Date
Sun May 01 2011
Journal Name
Information Sciences
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Publication Date
Sun Jul 24 2022
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Assessment of Smoking Dependence by FAGERSTRŐM Test and its Association with Some Comorbidities and Educational level

Background: Nicotine addiction is the inevitable result for many smokers. Regardless of control and intervention strategies for smoking cessation, it is important to determine the nicotine dependence score for each smoker. 

Objectives: To assess the nicotine dependence by FAGERSTRŐM Test for nicotine dependence (FTND score) and to find out the association of nicotine dependence with some smoking-related comorbidities and with the level of education.

Patients and Methods: This is a cross-sectional study on a total of 200 adult smokers who were attending different departments in Al-Imamain Al-Kadhimain Medical City during the period from April 2019 to October 2019. Demograp

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Publication Date
Mon Jan 02 2006
Journal Name
Journal Of The Faculty Of Medicine Baghdad
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