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Association between Aggregatibacter actinomy-cetemcomitans bacterial load and NLRP3 inflam-masome activation in periodontitis patients with Diabetes
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Abstract: Background: Aggregatibacter actinomycetemcomitans is one of the most common periodontal pathogen that has a direct effect on periodontium. Diabetes and periodontitis considered as chronic diseases with a bidirectional relationship between them. Evidence has shown that the Node Like Receptor Pyrine-3  inflammasome, is crucial for both illnesses. Aim of study: This investigation was conducted to observe the association between bacterial load of A. actinomyctecomtans and serum level of NLRP3 inflammasome in periodontitis patient with and without type 2 DM and control group. Materials and Methods: This case-control study included 85 participants, whose ages ranged from (23-55) years. Split into three groups; the control group, which had a clinically and systemically healthy periodontium, and the two groups with periodontitis, one of which also had type 2 DM. Samples of the four most profound periodontal pockets were sampled for subgingival plaque, and from the gingival sulcus in the control group. The real-time (PCR) was utilized in this experiment. to quantify A. actinomyctecomtans DNA was isolated from samples of dental plaque. All subjects' serum was collected, and the concentration of NLRP3 was measured using an ELISA technique. Results: The results showed that the bacterial count was higher in two groups of patient than the control group, but there were no-significant differences. On the other hand, there was a significant correlation between the bacterial count and periodontal parameters in periodontitis with type 2 DM group, while in periodontitis group there was positive correlation with clinical attachment loss and bleeding on probing. A significant positive correlation also noticed between NLRP3 inflammasome and periodontal parameters in periodontitis patient with type2 DM. Regarding the group of periodontitis patients without systemic disease there was no significance correlation between inflammasome and clinical parameters. Finally, there is a non-significant correlation of A. actinomyctecomtans with inflammasome. Conclusions: A. actinomyctecomtans detection rate was strongly higher in patient groups compared to healthy subjects but statically non-significant. Moreover, the lack of correlation between A. actinomyctecomtans and the NLRP3 inflammasome indicates that NLRP3 activation is associated   with inflammatory processes that are induced by a number of external factors, other than bacteria.

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Publication Date
Sun Apr 30 2023
Journal Name
Iraqi Journal Of Science
Doubly Type II Censoring of Two Stress-Strength System Reliability Estimation for Generalized Exponential-Poisson Distribution
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 In this paper, a Bayesian analysis is made to estimate the Reliability of two stress-strength model systems. First: the reliability  of a one component strengths X under stress Y. Second, reliability  of one component strength under three stresses. Where X and Y are independent generalized exponential-Poison random variables with parameters (α,λ,θ) and (β,λ,θ) . The analysis is concerned with and based on doubly type II censored samples using gamma prior under four different loss functions, namely   quadratic loss function, weighted loss functions,  linear and non-linear exponential loss function. The estimators are compared by mean squared error criteria due to a simulation study. We also find that the mean square error is

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Publication Date
Thu Apr 27 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
On A Bitopological (1,2)*- Proper Functions
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   In this paper, we introduce a new type of functions in bitopological spaces, namely, (1,2)*-proper functions. Also, we study the basic properties and characterizations of these functions . One of the most important of equivalent definitions to the (1,2)*-proper functions is given by using (1,2)*-cluster points of filters . Moreover we define and study (1,2)*-perfect functions and (1,2)*-compact functions in bitopological spaces and we study the relation between (1,2)*-proper functions and each of (1,2)*-closed functions , (1,2)*-perfect functions and (1,2)*-compact functions and we give an example when the converse may not be true .
 

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Publication Date
Tue Oct 20 2020
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Comparison Among Three Estimation Methods to Estimate Cascade Reliability Model (2+1) Based On Inverted Exponential Distribution
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      In this paper, we are mainly concerned with estimating cascade reliability model (2+1) based on inverted exponential distribution and comparing among the estimation methods that are used . The maximum likelihood estimator and uniformly minimum variance unbiased estimators are used to get  of the strengths  and the stress ;k=1,2,3 respectively then, by using the unbiased estimators, we propose Preliminary test single stage shrinkage (PTSSS) estimator when a prior knowledge is available for the scale parameter as initial value due past experiences . The Mean Squared Error [MSE] for the proposed estimator is derived to compare among the methods. Numerical results about conduct of the considered

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Publication Date
Fri Apr 01 2016
Journal Name
Journal Of Economics And Administrative Sciences
Financial investment strategies – Conceptual Framework
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The investor needs to a clear strategy for the purpose of access to the financial market, that is, has a plan to increase The share of the profits thinking entrepreneur and new, and highlights the importance of this in that it sets for the investor when it goes to the market, and when it comes out of it, and at what price to buy or sell the stock, and what is the the amount of money it starts. Fortunately, he does not need to invent his own investment strategy, because over the years the development of effective methods of buying and selling, and once you understand how to work these methods investor can choose the most appropriate methods and adapted image that fit his style investment .

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Publication Date
Mon Apr 15 2024
Journal Name
Nibal
يعتبر الاتصال وسيلة هادفة من الوسائل الرئيسية التي تستخدمها المنظمة الإدارية في تحقيق أهدافها إذ أن جميع العاملين يتعاملون مع بعضهم البعض من خلال وسائل الاتصال المختلفة من أجل ضمان تسيير نشاطاتهم وتحقيق أهدافهم وهذا يدل على أن الاتصال يعتبر الوسيلة الاجتماعية التي يحقق الأفراد من خلالها سبل التفاهم والتفاعل البناء
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Publication Date
Thu Aug 01 2019
Journal Name
Journal Of Economics And Administrative Sciences
مقارنة مقدرات بيز لدالة المعولية لتوزيع باريتو من النوع الاول باستعمال دوال معلوماتية مضاعفة مختلفة
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The comparison of double informative priors which are assumed for the reliability function of Pareto type I distribution. To estimate the reliability function of Pareto type I distribution by using Bayes estimation, will be  used two different kind of information in the Bayes estimation; two different priors have been selected for the parameter of Pareto  type I distribution . Assuming distribution of three double prior’s chi- gamma squared distribution, gamma - erlang distribution, and erlang- exponential distribution as double priors. The results of the derivaties of these estimators under the squared error loss function with two different double priors. Using the simulation technique, to compare the performance for

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