Background:
To assess the feasibility and early results of non-surgical transcatheter closure of atrial septal detect (ASD) using the Ampiatzer septal Occluder (ASO).
Patients and Methods:
From June 2003 to June 2005, i75 patients with ASD secundum, age range 3- 65 years, female to male ratio of 3:2. were evaluated for transcatheter closure using ASO at Ibn Al-
Bitar Hospital for Cardiac Surgery. Transthoracic echocardiography was performed in al patients using standard suhxyphoid, apical, parasternal and suprasternal views. In all
patients, the procedure was done under general anesthesia.
Results:
Based on transesophageal echocardiography (TEE) Findings, 60 patients (33.7%) did not meet the criteria for transcatheter closure (40 females and 20 males). One hundred
Fifteen patients were found to have ASDs suitable for device closure. The device was successfully deployed in allpatients except 11 of them (104/115) (90.4%).
In 11 cases with failure of ASO deployment, 6 patients had small floppy inferior rims which were not able to hold the device after the Minnesota wegeal maneuver. One adult
patient with a large ASD secundum and second degree AV block developed complete heart block during the procedure before the deployment of the occluder. One of them dislodged
into the left atrium (LA) immediately after deployment because of a very small inferior rim and the other one dislodged into the LA because of descrewing of the cable after multiple
manipulations. Both of them were referred for surgery. An other one of the 11 patients had developed a thrombus in the LA during the procedure because of delay in giving heparin
after placing the guide wire in the left upper pulmonary vein. In the last patient, the procedure was abandoned and the occluder recaptured into the sheath before release from
the cable because the TEE showed that the LA disc encroached on the mitral valve causing mitral stenosis.
Conclusion:
The transcatheter closure of secundum ASD is safe, efficacious with a very low rate of early and Sate complications. It is becoming an increasingly popular alternative to surgical
closure.
In this paper the research represents an attempt of expansion in using the parametric and non-parametric estimators to estimate the median effective dose ( ED50 ) in the quintal bioassay and comparing between these methods . We have Chosen three estimators for Comparison. The first estimator is
( Spearman-Karber ) and the second estimator is ( Moving Average ) and The Third estimator is ( Extreme Effective Dose ) . We used a minimize Chi-square as a parametric method. We made a Comparison for these estimators by calculating the mean square error of (ED50) for each one of them and comparing it with the optimal the mean square
In this research, Artificial Neural Networks (ANNs) technique was applied in an attempt to predict the water levels and some of the water quality parameters at Tigris River in Wasit Government for five different sites. These predictions are useful in the planning, management, evaluation of the water resources in the area. Spatial data along a river system or area at different locations in a catchment area usually have missing measurements, hence an accurate prediction. model to fill these missing values is essential.
The selected sites for water quality data prediction were Sewera, Numania , Kut u/s, Kut d/s, Garaf observation sites. In these five sites models were built for prediction of the water level and water quality parameters.
In this research, a type of gram negative bacteria was exposed to non-thermal plasma at a distance of (2 and 3 cm) from the plasma flow nozzle, with the use of an alternating power supply (5KHz), where exposure was made at two different voltages (4.9 and 8 kV). A negative gram of Pseudomonas aeruginosa bacteria was isolated and exposed to non-thermal plasma at different flow rates of argon gas whose value ranged from (1-5) liters/minute. The results showed that bacterial killing rate is directly proportional to distance while exposing the samples to non-thermal plasma, and the best factors by which a complete killing rate was obtained were at a distance of 2 cm with a voltage of 8 kV and a gas flow rate of 5 liters/min,
... Show MoreIn real situations all observations and measurements are not exact numbers but more or less non-exact, also called fuzzy. So, in this paper, we use approximate non-Bayesian computational methods to estimate inverse Weibull parameters and reliability function with fuzzy data. The maximum likelihood and moment estimations are obtained as non-Bayesian estimation. The maximum likelihood estimators have been derived numerically based on two iterative techniques namely “Newton-Raphson†and the “Expectation-Maximization†techniques. In addition, we provide compared numerically through Monte-Carlo simulation study to obtained estimates of the parameters and reliability function i
... Show MoreDNA methylation is one of the main epigenetic mechanisms in cancer development and progression. Aberrant DNA methylation of CpG islands within promoter regions contributes to the dysregulation of various tumor suppressors and oncogenes; this leads to the appearance of malignant features, including rapid proliferation, metastasis, stemness, and drug resistance. The discovery of two important protein families, DNA methyltransferases (DNMTs) and Ten-eleven translocation (TET) dioxygenases, respectively, which are responsible for deregulated transcription of genes that play pivotal roles in tumorigenesis, led to further understanding of DNA methylation-related pathways. But how these enzymes can target specific genes in different malignancies;
... Show MoreThe research aims to identify the extent of the impact of non-Iraqi trading of shares in the Iraq Stock Exchange on the overall financial investment in the market size. And it imposes a search and no statistically significant relationship between variable trading non-Iraqis, the size and the total volume of the market and took the search Iraq Stock Exchange sample to search being the only private place to trade securities in Iraq for the period of 2009- 2015 in order to see if there is a positive impact on the size of trading non-Iraqis or not. Search and adopted the annual reports issued by the Iraq Stock Exchange the main conclusion are:
Having a positive effect on the size of the trading of non-Iraqis in the financial vo
... Show MoreAim: This study aimed to assessing orthodontic knowledge and attitude among general dentists and non-orthodontic specialists. Background: Early detection of orthodontic disorders is essentialin motivating patients to intervene prior to long term complications when the disorders are not recongised. Methods: A questionnaire was distributed amongst dentistsother than orthodontists. This questionnaire consisted of three sections. The first one aimed to collect demographic, educational level and practice type information. Further two sections consisted of closed-end questions designed to evaluateknowledge and attitude of orthodontics. Results: A total of 313 responses to the survey were submitted. No significant correlation was observed, e
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The research aims to measure, assess and evaluate the efficiency of the directorates of Anbar Municipalities by using the Data Envelopment Analysis method (DEA). This is because the municipality sector is consider an important sector and has a direct contact with the citizen’s life. Provides essential services to citizens. The researcher used a case study method, and the sources of information collection based on data were monthly reports, the research population is represented by the Directorate of Anbar Municipalities, and the research sample consists of 7 municipalities which are different in terms of category and size of different types. The most important conclusion reached by the research i
... Show MoreCoagulation - flocculation are basic chemical engineering method in the treatment of metal-bearing industrial wastewater because it removes colloidal particles, some soluble compounds and very fine solid suspensions initially present in the wastewater by destabilization and formation of flocs. This research was conducted to study the feasibility of using natural coagulant such as okra and mallow and chemical coagulant such as alum for removing Cu and increase the removal efficiency and reduce the turbidity of treated water. Fourier transform Infrared (FTIR) was carried out for okra and mallow before and after coagulant to determine their type of functional groups. Carbonyl and hydroxyl functional groups on the surface of
... Show MoreAbstract
Background
Stathmin1 (also known as metablastin) is a major microtubule-depolymerizing protein that involved in cell cycle progression and cell motility.
Stathmin1 has been found to be up-regulated in some cancers and correlated with cell differentiation and proliferation.
Stathmin1 is a major cytosolic phosphoprotein that regulates microtubule dynamics and is associated with malignant phenotypes in various cancers, including non-small cell lung cancer.
Objective
To evaluate the role of Immunohistochemical expression of stathmin1 in non-small
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