Breast cancer is the most prevalent malignancy among women worldwide, in Iraq it ranks the first among the population and the leading cause of cancer related female mortality. This study is designed to investigate the correlations between serum and tissue markers in order to clarify their role in progression or regression breast cancer. Tumor Markers are groups of substances, mainly proteins, produced from cancer cell or from other cells in the body in response to tumor. The study was carried out from April 2018 to April 2019 with total number of 60 breast cancer women. The blood samples were collected from breast cancer women in postoperative and pretherapeutic who attended teaching oncology hospital of the medical city in Baghdad and the serum markers evaluated by ELISA technique are Carbohydrate Antigen 15-3 (Ca 15-3), Carbohydrate Antigen 27.29 (Ca 27.29), Anti-Mullerian Hormone (AMH), Tumor Necrosis Factor-Alpha (TNF-α), Interleukin-6 (IL-6), Interleukin-10 (IL-10) and Human Epidiymis Protein-4 (HE4). Tissue samples were collected for the same breast cancer women who attended medical city, Baghdad with total number 30. The tissue markers evaluated by Immunohistochemical technique are Estrogen Receptor (ER), Progesterone Receptor (PR), Human Epidermal Growth Factor Receptor 2 (Her 2/neu) and Cyclin E. The results showed a positive significant correlation (p = 0.017) between Ca 27.29 and Her-2/neu, (p = 0.038) between IL-6 and cyclin E phenotype, (p = 0.051) between TNF-α and Cyclin E intensity, (p = 0.005) between HE4 and Her-2/neu, and negative significant correlation (p = 0.058) between IL-10 and ER score and (p = 0.045) between HE4 with Cyclin E intensity. We conclude from these correlations that positive correlations increasing disease progression, like correlation between Ca 27.29 and Her-2/neu, cyclin E with IL-6 and cyclin E with TNF-α. And the negative correlations may contribute to delay disease, like correlation between IL-10 and ER. From the correlations results in this study, it is clear that the Ca 27.29, Her-2 / neu, cyclin E markers play an important role in disease progression.
مشكلة البحث واهميته:-
اخذ موضوع العولمة قدراً وافياً من الاهتمام سواء على المستوى الاكاديمي او على مستوى اجهزة الاعلام والرأي العام ومختلف التيارات السياسية والاقتصادية والاجتماعية ، فلا يخلو أي لقاء اقتصادي او سياسي او اجتماعي من الحديث عن العولمة اذ نشرت العديد من الابحاث والدراسات وعقدت الكثير من الندوات والمؤتمرات لدراسة العولمة وبيان اثارها ولعل ذل
... Show Moreان تقدير مسؤولية المحاسب في تصميم نظام المعلومات المحاسبي من منظور تاريخي سبقت استخدام الحاسوب كأداة معلوماتية للاعمال، لما له من رؤيا بالتطورات الرئيسية لنظام المعلومات والتي اهمها تحديد متطلبات مستخدمي المعلومات وتعيين مضمون وشكل مخرجات النظام من التقارير وتحديد مصادر البيانات وانتقاء القواعد المحاسبية الملائمة فضلاً عن الرقابة الضرورية لتكامل وفاعلية النظام.
ان النظم المحاسبية التقليدية غالبا
... Show MoreThe research aims to show the impact of the new modern malls on urban adjacent land uses; it handled concise study of the old markets, contemporary shopping malls, and the standards and regulations for commercial use. Sample study has been taken from new allocated malls in the city of Baghdad. The results of the sample analysis, and statistical analysis has proven hypothesis; that the locating of new malls impacted physical, social, and economic on urban adjacent, especially the exotic on urban fabric. It also turned out that the shopping demand from these malls is inelastic, which gives an opportunity to the planner and the decision-maker, to locate the modern new malls where spatial appropriate in the city are available. The major reco
... Show Moreيعد الرثاء أساساً من أسس الموروث الشعري العربي، وهو باب من أبواب الشعر الرئيسة. وقد وجد الإنسان فيه بغيته في التعبير عن مكنون نفسه ساعة تكتظ بالألم، ومنفذاً يخرج منه لواعجه وأشجانه إلى الخارج في شكل تعبيري يحرر الدمعة، ويعاتب الموت. والرثاء غرض متطور ينمو مع نمو المجتمع والحياة ويسجل التغيير الذي يحصل في كل مرحلة من مراحل التاريخ، وهو نتيجة مهمة من نتائج اصطدام الشاعر بالحياة والأحداث. لهذا وقع اختياري على شع
... Show MoreConcurrent Engineering approved that it is distinguished technology efficiency as it reflect its affection on international great companies . Its becomes vital field connected with its ability to develop the products directly, as well as, its concentration on all local and international competition which need to research and expanded
This study deals with (concurrent engineering) subject in
(Dyala State Company for Electrical Industry) , to bring the benefits of this technology to develop 
تزداد أهمية وجود اللغة العربية على الشبكات الحاسوبية مع توجه المجتمع نحو مجتمع المعلومات, ونحو الاقتصاد المبني على المعرفة. ويصطلح عالمياً على هذا الوجود بكلمة المحتوى, فكيف يمكن أن نزيده
This research aims to present a range of views and beliefs about the climate that have prevailed spontaneously in the Iraqi society and, whether agricultural or Bedouin communities and even popular communities within cities.
The development of human resources training programs has an applied and important role in the preparation of human cadresin terms of capacity to absorb technical sciences and skills and scientific and practical practices at faster rates in order to bealighed with continous development. Hence the recognition of the significant role that human resources play in the economy of any country,which has stressed the interest towards the economic unity of the qualified staff that it needsin atimely manner through the ongoing training process in the era of high technology day by day In this regard ,the current research deal with accounting of human resources and its impact on reducing costs in the military establishment and the
... Show Moreيهدف هذا البحث الى تحديد اثر الاختلاف في ادراكات العاملين للعدالة التنظيمية في المنظمات قيد البحث. وقد تم اعتماد الادراك كمتغير تفسيري، اما العدالة التنظيمية فمثلت المتغير الاستجابي بانواعها الثلاث (العدالة التوزيعية، العدالة الاجرائية، والعدالة التفاعلية)، ولتحقيق اهداف البحث فقد تم اختيار دائرة صحة بغداد/ الكرخ مجتمع للدراسة. وجرى تصميم استبانة ووفق مقياس خماسيي الدراجات وجرى تحليل البيانات باستخ
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