Breast cancer is the most prevalent malignancy among women worldwide, in Iraq it ranks the first among the population and the leading cause of cancer related female mortality. This study is designed to investigate the correlations between serum and tissue markers in order to clarify their role in progression or regression breast cancer. Tumor Markers are groups of substances, mainly proteins, produced from cancer cell or from other cells in the body in response to tumor. The study was carried out from April 2018 to April 2019 with total number of 60 breast cancer women. The blood samples were collected from breast cancer women in postoperative and pretherapeutic who attended teaching oncology hospital of the medical city in Baghdad and the serum markers evaluated by ELISA technique are Carbohydrate Antigen 15-3 (Ca 15-3), Carbohydrate Antigen 27.29 (Ca 27.29), Anti-Mullerian Hormone (AMH), Tumor Necrosis Factor-Alpha (TNF-α), Interleukin-6 (IL-6), Interleukin-10 (IL-10) and Human Epidiymis Protein-4 (HE4). Tissue samples were collected for the same breast cancer women who attended medical city, Baghdad with total number 30. The tissue markers evaluated by Immunohistochemical technique are Estrogen Receptor (ER), Progesterone Receptor (PR), Human Epidermal Growth Factor Receptor 2 (Her 2/neu) and Cyclin E. The results showed a positive significant correlation (p = 0.017) between Ca 27.29 and Her-2/neu, (p = 0.038) between IL-6 and cyclin E phenotype, (p = 0.051) between TNF-α and Cyclin E intensity, (p = 0.005) between HE4 and Her-2/neu, and negative significant correlation (p = 0.058) between IL-10 and ER score and (p = 0.045) between HE4 with Cyclin E intensity. We conclude from these correlations that positive correlations increasing disease progression, like correlation between Ca 27.29 and Her-2/neu, cyclin E with IL-6 and cyclin E with TNF-α. And the negative correlations may contribute to delay disease, like correlation between IL-10 and ER. From the correlations results in this study, it is clear that the Ca 27.29, Her-2 / neu, cyclin E markers play an important role in disease progression.
Abstract: Various peoples have contributed to building the Islamic civilization through the achievements and creativity of their scholars. In particular, the Kurdish scholars have provided new and great services to the Holy Qur’an that deserves attention. For example, it is no secret that Sheikh Ahmadian, with his interpretation, rendered a great service to the Glorious Book of God. His style is distinguished by modernity, seriousness and objectivity, and represents a lively response to the needs of the Kurdish Muslim people. Due to the importance of Ahmadian’s interpretation of the Qur’an, therefore, I have demonstrated his approach in this research in terms of dealing with his interpretation of the Qur’an with the Qur’an, the
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Conservation of Concept among Children: Semantic Study
Standards of audit have been defined issued them by professional organizations the audit risk is: Failure of the auditor inadvertently to amend his opinion on the financial statements in suitable method, although these statements are Interpolated Essentially. As result the deep impacts caused by electronic operating systems in the accounting data in the audit process which audit risk has gained attention of many professional sides, especially the audit process and quality is relating with level of discovery the auditor for the mistakes of origin (misrepresentations) all their types and give the necessary confidence for the auditor to express his technical opinion in fidelity and certified financial statements which prepared electronicall
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Los lingüistas no árabes suelen quedar perplejos a la hora de interpretar el fenómeno de Al-ḍdad, −normalmente traducido en español como palabras autoantónimas (1)− en la lengua árabe, en el que los arabistas, y entre ellos los españoles, han quedado sombrosos ante este fenómeno. El jefe del tribunal de la defensa de mi tesis me pidió que le explicara este fenómeno según mi teoría “El esquema básico de la referencia”; pues me dijo que no podía imaginar que una palabra tuviera dos significados opuestos, y en ese momento le expliqué la palabra albayn البين que significa la separación, o la relación o el enlace que comentar
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أعددت العدة لتسليط الضوء على خصوصية اختيار أداةاستفهام دون غيرها من الأدوات التي يصح أن تنوب عنها،مع التأكيد على ما يكمن وراء المعنى المجازي من مضمون. يفس: ر خصوصية الاستفهام وفضله في التعبير( وهذه المنهجية انصبت على15)?خمسة عشر موضعا(استفهام في استفهاميا ? في السورة المباركة ،وزعتها بين) ( )استفهام في الخطاب البشري ، وقد و الخطاب الإلهي) ( ) (زمام المعاني باقتدار، الإنكار و التعجب أمسك فيها غرضاولعل ذلك يناسب سورة
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يقف البحث الموسوم (تجربة الاختيار في الشعر الجاهلي وصدر الاسلام)، على العديد من النماذج الشعرية، التي عاش فيها الشاعر العربي تجربة الاختيار في العصر الجاهلي وصدر الاسلام، واتجه البحث الى تحليل العديد من النماذج المختارة من التراث العربي الشعري، وقد وقف البحث على بعض التجارب التي يقع فيها الشاعر في موقف الاختيار. و لذلك كان من المنطق ان يقسم البحث الى مبحثين: فكان الاول منها يقف على (تجربة الاختيار في الشعر
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