Breast cancer is the most prevalent malignancy among women worldwide, in Iraq it ranks the first among the population and the leading cause of cancer related female mortality. This study is designed to investigate the correlations between serum and tissue markers in order to clarify their role in progression or regression breast cancer. Tumor Markers are groups of substances, mainly proteins, produced from cancer cell or from other cells in the body in response to tumor. The study was carried out from April 2018 to April 2019 with total number of 60 breast cancer women. The blood samples were collected from breast cancer women in postoperative and pretherapeutic who attended teaching oncology hospital of the medical city in Baghdad and the serum markers evaluated by ELISA technique are Carbohydrate Antigen 15-3 (Ca 15-3), Carbohydrate Antigen 27.29 (Ca 27.29), Anti-Mullerian Hormone (AMH), Tumor Necrosis Factor-Alpha (TNF-α), Interleukin-6 (IL-6), Interleukin-10 (IL-10) and Human Epidiymis Protein-4 (HE4). Tissue samples were collected for the same breast cancer women who attended medical city, Baghdad with total number 30. The tissue markers evaluated by Immunohistochemical technique are Estrogen Receptor (ER), Progesterone Receptor (PR), Human Epidermal Growth Factor Receptor 2 (Her 2/neu) and Cyclin E. The results showed a positive significant correlation (p = 0.017) between Ca 27.29 and Her-2/neu, (p = 0.038) between IL-6 and cyclin E phenotype, (p = 0.051) between TNF-α and Cyclin E intensity, (p = 0.005) between HE4 and Her-2/neu, and negative significant correlation (p = 0.058) between IL-10 and ER score and (p = 0.045) between HE4 with Cyclin E intensity. We conclude from these correlations that positive correlations increasing disease progression, like correlation between Ca 27.29 and Her-2/neu, cyclin E with IL-6 and cyclin E with TNF-α. And the negative correlations may contribute to delay disease, like correlation between IL-10 and ER. From the correlations results in this study, it is clear that the Ca 27.29, Her-2 / neu, cyclin E markers play an important role in disease progression.
This study identified intellectual and applied research in key variables (Strategic Control and Strategic Pitfalls) through internal dimensions then founded the (Federal Board of Supreme Audit) is the good area for analyzing the relationship and effect between variables by (125) questionnaire selected from (148) was distributed to the top and middle management as a seniors in controlling action. Appropriate methods, statistical tools, and programs were used to enhance the basic outputs, represented as a set of Conclusions and recommendations from the real control work with a specificity of potential Pitfalls in the effectiveness impact by Strategic Control in other dimensions which Studied.
تهدف هذه دراسه
The purpose of this research that, the performance budget is the best style of budget styles that can help and contribute in forming preparing federal typical budget in Iraq , By taking advantage of the application of the principles of scientific rules that would ensure optimal allocation and investment of the financial resources of the state and achieve the best performance and the lowest possible cost, both with regard to the administrative and accounting side, reducing the waste of public money, so that can enhance the success , power , and safety of financial activity of managerial system that it focuses on the magnetite and quality of the work done and the objectives wanted to meet. so application of performance budget require
... Show Moreجديرة تلك المجلة العريقة (Journal of management history) لما تقوم به من دور متميز في تأصيل الفكر الاداري وتنسيب الموضوعات لأصحابها الحقيقيين. فالمجلد (12)، العدد (3) لعام (2006) من هذه المجلة حمل مراجعة تاريخية كبيرة لعنوان عميق هو
(The emergence of job satisfaction in organization behavior A historical overview of the dawn of jop attitudes research)، للباحث (Thomas A. Wright) الاستاذ في قسم العلوم الادارية بجامعة نيف
تحتكم العملية البنائية في المنجز الخطي الى م6جموعة من العوامل والمتغيرات المترابطة بتسلسل منطقي، لتنتج رؤية موحدة لإنجاز عمل فني تتوافر فيه الابعاد الوظيفية والجمالية والتعبيرية، ففي بنائية النسق الفني ليس المهم هو العنصر بقدر أهمية نظام العلاقات الذي يجعل هذا العنصر البنائي ينسجم مع باقي العناصر، وبالتالي تبرز قيمته كونه داخل بنية تنطوي على ضبط مكوناتها بدقة، لتفضي الى تقديم منجز للمتلقي منبثق من رؤية فا
... Show Moreالمقدمة
تعد السياحة احد مستلزمات الحضارة الحديثة لما تفرزه من آثار ايجابية ودور متميز في دعم الاقتصاد الوطني وتقليل نسبة البطالة وتنشيط الحركة التجارية بين البلدان، اذ لا يمكن ان نتصور وجود بلد متحضر بلا فنادق ولا سياحة وتقديم مختلف السلع والخدمات سياحية التي يمكن ان تسبع الحاجات والرغبات واذواق السياح من خلال وجود منشآت سياحية تعكس النمط السياحي القائم على اختلاف انواعه
... Show MoreEpistemological skepticism was present strongly in the Islamic
philosophical heritage. Many texts were received by thinkers and
philosophers calling for
تنبع أهمية البحث من أهمية الخبرات اللغوية التي يكتسبها الأطفال في مرحلة الرياض لما لها من أهمية بالغة في تطوير النمو اللغوي لطفل الرياض وزيادة ذخيرته اللغوية في المرحلة المستقبلية القادمة.
أن ما يكتسبه الطفل في مرحلة الرياض من ألفاظٍ وكلمات تساعد على تنمية محصوله اللغوي وتمكنهُ من النطق اللغوي السليم وتطوير قابليتهِ على تكوين الجُمل والعبارات السليمة التي تُمهد لدخولهِ المرحلة الابتدائ
... Show MoreThe Heritage geographical Arab-Muslim of great value in the history of the evolution of thought geographical The themes of cities, like other subjects heritage books geographical Islamic related to geography descriptive and regional were subject to the style of Arabic writing,