Breast cancer is the most prevalent malignancy among women worldwide, in Iraq it ranks the first among the population and the leading cause of cancer related female mortality. This study is designed to investigate the correlations between serum and tissue markers in order to clarify their role in progression or regression breast cancer. Tumor Markers are groups of substances, mainly proteins, produced from cancer cell or from other cells in the body in response to tumor. The study was carried out from April 2018 to April 2019 with total number of 60 breast cancer women. The blood samples were collected from breast cancer women in postoperative and pretherapeutic who attended teaching oncology hospital of the medical city in Baghdad and the serum markers evaluated by ELISA technique are Carbohydrate Antigen 15-3 (Ca 15-3), Carbohydrate Antigen 27.29 (Ca 27.29), Anti-Mullerian Hormone (AMH), Tumor Necrosis Factor-Alpha (TNF-α), Interleukin-6 (IL-6), Interleukin-10 (IL-10) and Human Epidiymis Protein-4 (HE4). Tissue samples were collected for the same breast cancer women who attended medical city, Baghdad with total number 30. The tissue markers evaluated by Immunohistochemical technique are Estrogen Receptor (ER), Progesterone Receptor (PR), Human Epidermal Growth Factor Receptor 2 (Her 2/neu) and Cyclin E. The results showed a positive significant correlation (p = 0.017) between Ca 27.29 and Her-2/neu, (p = 0.038) between IL-6 and cyclin E phenotype, (p = 0.051) between TNF-α and Cyclin E intensity, (p = 0.005) between HE4 and Her-2/neu, and negative significant correlation (p = 0.058) between IL-10 and ER score and (p = 0.045) between HE4 with Cyclin E intensity. We conclude from these correlations that positive correlations increasing disease progression, like correlation between Ca 27.29 and Her-2/neu, cyclin E with IL-6 and cyclin E with TNF-α. And the negative correlations may contribute to delay disease, like correlation between IL-10 and ER. From the correlations results in this study, it is clear that the Ca 27.29, Her-2 / neu, cyclin E markers play an important role in disease progression.
جاءت هذه الورقة البحثية لتبين اهمية التلفزيون في حياة النشىء من حيث بناء شخصيته واكسابه مايلزم من المهارات التي تعدهم الاعداد الافضل للحياة في حاضرها ومستقبلها ولتظهر دوره كوسيلة تعليمية معينة يمكن الاستفادة منها في العملية التربويةفي البيت والروضة والمدرسة ولتواكب مراحل حياة الاطفال وخصائص النمو العقلي والجسمي والانفعالي في كل مرحلة
يتكون العالم ، أنذاك ، من دارين - دار الإسلام حيث الأقاليم الإسلامية ودار الحربوهي بلاد المشركين الذين لا صلح بينهم وبين المسلمين (1) ، أي ما خضع للعدو ضمن حدود سيادته ، ولكن عندما يحتفظ أهالي البلاد المفتوحة صلحاً بحقوق ملكية الأرض فأنه ،على رأي الماوردي ، يصبح خراجهم جزية ولا جزية على رؤوسهم(2) ولهم حرية تبايع أرضهم فيما بينهم أو بيعها للمسلمين أو لأهل الذمة (3) . ولا يمكن أن تعد أرضهم
... Show MoreWestern political philosophy is one of the philosophies that dealt with many ideas and proposals that include concepts born in ancient times, where Greek philosophy represents the basic roots of the development of political thought and the study of political phenomena and a starting point for political thought, and if the matter is completed with the Romans, and schools of thought that represented a model for building the state And up to the modern era, the absolute and the relative were the subject of discussion by most philosophers, the transition of thought was with Descartes, and the intellectual transformation from the absolute to the relative was with Nietzsche, and the basic root of all of that is represented by the German philoso
... Show Moreاشكالية النظرية في العلوم السياسية : مساهمة اولية
تناول هذا البحث الدور الحيوي الذي تؤديه المراكز البحثية في دعم القضايا الاجتماعية، مع التركيز على مركز دراسات المرأة في جامعة بغداد كنموذج تطبيقي. يوضح الباحث أن هذه المراكز لا تقتصر على إنتاج المعرفة النظرية، بل تسهم بشكل مباشر في معالجة التحديات المجتمعية، من خلال تقديم رؤى تحليلية ومقترحات عملية لصناع القرار. كما ويسلط الضوء على مساهمة مركز دراسات المرأة في تعزيز المشاركة السياسية للمرأة العراقية، خاصة
... Show MoreThe line is among a nation of civilized nations did not attain what Muslims took care
Affected by agricultural products in the Levant to a lot of factors that led to the rise in prices which as a result of natural factors, the most important and most notably the earthquakes that occurred in the dates of sporadic in the Levant,
الرؤية السايكلوجية وتطبيقاتها في مسرحية الشيخ والغانية
Appearance of the Kurdish press in the Kurdish literature was affected by as set of both external and internal factors. The former was realized in the spreading of press and publications especially at the neighboring countries in the second half of the 19th century. The latter factors, external ones ,were concerned the political situations undergone by the Kurdish people who severely suffered injustice practiced by the Othman authority .All these reasons had driven the educated to migrate to search for more safe places to practice their cultural actions with absolute freedom. Consequently, the first newspaper was issued on 22/4/1898 in Cairo which pointed the birth of the Kurdish press inside and outside Kurdistan region which
... Show MoreThe Fatimids were arguing with the Abbasids in everything, even in the causes of civilization, and the Islamic moderization had matured,