Rheumatoid arthritis and periodontitis use analogous effector destructive procedures, in that the inflammatory cells and pro-inflammatory cytokines that drive chronic bone erosion in RA and chronic periodontal destruction in Periodontitis are alike. Periodontitis (PD) has appeared as a hazard factor in a number of health situations as rheumatoid arthritis (RA). To determine the effect of anti-tumor necrosis factor alpha biological treatment (methotrexate and Enbrel or infliximab) on periodontal status of patients having rheumatoid arthritis with periodontitis in comparison to those having periodontitis without rheumatoid arthritis and control healthy subjects and to determine the serum levels of anti-cyclic citrullinated peptide (ACCP) in these groups. Periodontal parameters used in this study were plaque index (PI), gingival index (GI), bleeding on probing (BOP) and clinical attachment level (CAL). Serum levels of anti-cyclic citrullinated peptide (ACCP) was estimated by enzyme linked immunosorbent assays (ELISA). The Blood samples were gathered from 75 patients (25 patients had rheumatoid arthritis with periodontitis, 30 patients with periodontitis only and 20 evidently healthy volunteers). The current data revealed that the median value of plaque and gingival indices were higher in the periodontitis group than in rheumatoid arthritis with periodontitis group while CAL was slightly higher in rheumatoid arthritis with periodontitis group than periodontitis group. The percentage of BOP sites were higher in periodontitis group than rheumatoid arthritis with periodontitis. The serum level of anti-cyclic citrullinated peptide was found to be higher in the periodontitis group (601.846) followed by rheumatoid arthritis with periodontitis, which had the lowest median (163.99), while the median value of ACCP in control group was (218.617), and the result was statistically non-significant difference between the study groups p> 0.05. There was no correlation between anticyclic citrullinated peptide and clinical periodontal parameters in each group except in gingival index, bleeding on probing of the periodontitis group as there was significant correlation. Patients with RA receiving biological treatment had lower anti_cyclic citrullinated peptide antibody and lower periodontal indices when compared with the other patient that not taking biological therapy. Thus, suppression of pro-inflammatory cytokines might have a beneficial effect in reducing inflammatory activity in rheumatoid arthritis disease and in minimizing the periodontal destruction of chronic periodontitis.
Abstract
There have been a number of positive developments in inclusive education in many different countries, recognizing that all students, including those with disabilities, have a right to education. Around the world, educators, professionals, and parents are concerned about including children with disabilities in mainstream schools along with their peers. As a result of this trend, a number of factors are contributing, including the increasing importance of education in achieving social justice for pupils with special education needs; the right of individuals with disabilities to attend mainstream schools together with their typically developing peers; the benefit of equal opportunities for everyone in achie
... Show MoreThe research aims to identify the level of balance in the architectural thought influenced by the rational type human consciousness, the materialistic based on the Empirical type, moral based on human experience as source of knowledge.
This was reflected in architecture in the specialized thought that the mind is the source of knowledge which explains the phenomena of life. The rational approach based on objectivity and methodology in (Form Production), the other approach is based on subjectivity in form production (Form Inspiration).
The research problem is that there is imbalance in the relationship between the rational side and the human experience in architecture, which led into imbalance between theo
... Show MoreIraq depends mainly on Tigris and Euphrates Rivers to provide high percentage of agricultural water use for thousands years. At last years, Iraq is suffering from shortage in water resources due to global climate changes and unfair water politics of the neighboring countries, which affected the future of agriculture plans for irrigation, added to that the lack of developed systems of water management in the irrigation projects and improper allocation of irrigation water, which reduces water use efficiency and lead to losing irrigation water and decreasing in agricultural yield. This study aims at studying the usability of irrigation and leaching scheduling within the irrigating projects and putting a complete annual or seasonal irrigatio
... Show MoreWe notice that the issue of development is one of the most important issues in ourepoch especially in our country which classify within back ward countries.
When we talk here about the development we don’t mean only the development of capitals or the development of products.but the most important thing is the development of mind .if we notice the experience of developits economy and it didn’t reach to the wanted aim.because these sides . The highness of the meutal rate of the nation is the standard of of the nation is the standard of the sentific and cultural advance for this nation .And that is what we have noticed in human societies ingenerall .
We noticed that
... Show MoreA space X is named a πp – normal if for each closed set F and each π – closed set F’ in X with F ∩ F’ = ∅, there are p – open sets U and V of X with U ∩ V = ∅ whereas F ⊆ U and F’ ⊆ V. Our work studies and discusses a new kind of normality in generalized topological spaces. We define ϑπp – normal, ϑ–mildly normal, & ϑ–almost normal, ϑp– normal, & ϑ–mildly p–normal, & ϑ–almost p-normal and ϑπ-normal space, and we discuss some of their properties.
Long before the pandemic, labour force all over the world was facing the quest of incertitude, which is normal and inherent of the market, but the extent of this quest was shaped by the pace of acceleration of technological progress, which became exponential in the last ten years, from 2010 to 2020. Robotic process automation, work remote, computer science, electronic and communications, mechanical engineering, information technology digitalisation o public administration and so one are ones of the pillars of the future of work. Some authors even stated that without robotic process automation (RPA) included in technological processes, companies will not be able to sustain a competitive level on the market (Madakan et al, 2018). R
... Show MoreThroughout this paper R represents commutative ring with identity and M is a unitary left R-module. The purpose of this paper is to investigate some new results (up to our knowledge) on the concept of weak essential submodules which introduced by Muna A. Ahmed, where a submodule N of an R-module M is called weak essential, if N ? P ? (0) for each nonzero semiprime submodule P of M. In this paper we rewrite this definition in another formula. Some new definitions are introduced and various properties of weak essential submodules are considered.
Interval methods for verified integration of initial value problems (IVPs) for ODEs have been used for more than 40 years. For many classes of IVPs, these methods have the ability to compute guaranteed error bounds for the flow of an ODE, where traditional methods provide only approximations to a solution. Overestimation, however, is a potential drawback of verified methods. For some problems, the computed error bounds become overly pessimistic, or integration even breaks down. The dependency problem and the wrapping effect are particular sources of overestimations in interval computations. Berz (see [1]) and his co-workers have developed Taylor model methods, which extend interval arithmetic with symbolic computations. The latter is an ef
... Show MoreIn this paper is to introduce the concept of hyper AT-algebras is a generalization of AT-algebras and study a hyper structure AT-algebra and investigate some of its properties. “Also, hyper AT-subalgebras and hyper AT-ideal of hyper AT-algebras are studied. We study on the fuzzy theory of hyper AT-ideal of hyper AT-algebras hyper AT-algebra”. “We study homomorphism of hyper AT-algebras which are a common generalization of AT-algebras.