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Impact of Plasma Focal Adhesion Kinase, Ephrin Receptor Type A4, and Adiponectin in Patients with Acute Myeloid Leukemia
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Abstract<sec> <title>BACKGROUND:

Focal adhesion kinase (FAK), ephrin receptor type A4 (EphA4), and adiponectin (ADPN) are important indicators in inflammation, tumor growth, migration, and angiogenesis in some cancers. The predictive impact of their concentrations in acute myeloid leukemia (AML) patients to be identified remains. The research sought to explore the effect of FAK, EphA4, and ADPN as prognostic biomarkers, and their influence on patient survival, and to look for any potential correlation between their levels with hematological parameters in AML patients.

PATIENTS, MATERIALS, AND METHODS:

The study was carried out on 65 newly diagnosed adult de novo AML patients and 15 controls. Plasma levels were assayed by enzyme-linked immunosorbent assay at diagnosis. The overall survival (OS) was determined after 12 months.

RESULTS:

The FAK concentrations were significantly (P < 0.001) higher among AML patients than the controls. EphA4 level was insignificantly lower in AML patients than in control (P = 0.902), and insignificantly higher ADPN concentrations among AML patients than the control (P = 0.352). There were no significant differences between monocytic and nonmonocytic AML patients in FAK, EphA4, and ADPN levels. Regarding the OS, cases with lower than median levels of FAK were associated with a significant (P = 0.002) higher OS time in days, and cases with higher than median levels of EphA4 and ADPN had a significant (P = 0.007 and P = 0.039, respectively) higher OS time in days.

CONCLUSIONS:

FAK, EphA4, and ADPN can be used as noninvasive prognostic markers in AML patients with a possible role in AML pathogenesis, and resistance to chemotherapy.

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Publication Date
Wed Jun 29 2022
Journal Name
Journal Of The College Of Education For Women
Cognitive Motive of the Kindergarten Child
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Encouraging children towards the cognitive motivation through the discovery and knowledge of the environment around them is essential. Thus, during the two researchers’ supervision of the practical lessons that involved the female students’ application of their experience in the Applied Kindergarten Laboratory, it has been noticed that there was a difference in the cognitive motivation of kindergarten children. In order to reinforce the research problem, the two researchers sent an open questionnaire to a sample of randomly selected kindergarten teachers from Al-Karkh and Al-Rasafa sides. The responses collected accentuated the researchers’ sense of the existing problem. To achieve the aim of the study represented by examining the

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Publication Date
Sun Aug 01 2021
Journal Name
Materials Today: Proceedings
A review of automatic history matching
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Publication Date
Fri Mar 30 2007
Journal Name
Iraqi Journal Of Chemical And Petroleum Engineering
Testing of Drinking Water Reservoirs Coating
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The present study refers to a ready-made three components epoxy based paint made by the Modern Paints Industries Company (Al-Za'farania, Baghdad) subjected to several tests in order to improve its specifications by optimizing the application conditions. The paint components are under the trade names: Resin (D-5547), Hardener (H-1457) and Thinner (P-851). The paint is used for painting drinking water reservoirs from inside.

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Publication Date
Sun Mar 30 2014
Journal Name
Iraqi Journal Of Chemical And Petroleum Engineering
Structure Rheology of Polyethylene Oxide Solution
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Intrinsic viscosities have been studied for polyethylene oxide in water which has wide industrial applications. The polyethylene oxide samples had two different structures, the first one was linear and covers a wide range of molecular weight of 1, 3, 10, 20, 35, 99, 370, 1100, 4600, and 8000 kg/mol and the second one was branched and had molecular weights of 0.55 and 40 kg/mol.
Intrinsic viscosities and Huggins constants have been determined for all types and molecular weights mentioned above at 25ºC using a capillary viscometer. The values of Mark-Houwink parameters (K and a) were equal to 0.0068 ml/g and 0.67 respectively, and have not been published for this range of molecular weight in as yet.

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Publication Date
Sun Jul 01 1990
Journal Name
Bulletin Of The Iraq Natural History Museum (p-issn: 1017-8678 , E-issn: 2311-9799)
NEMATODE PARASITES OF SOME IRAQI BATS
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Three species of nematodes are recorded from alimentary tracts of some Iraqi bats for the first tithe, while reporting Thelandros alatus constitutes first record of this species from mammals. Information on infection rate, distribution and halts are provided along with some relevant remarks.

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Publication Date
Wed Oct 15 2014
Journal Name
Iraqi Journal Of Agricultural Sciences
Mechanism of plant salinity stress tolerance
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Publication Date
Tue Oct 30 2018
Journal Name
Civil Engineering Journal
Equivalent Modulus of Asphalt Concrete Layers
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A flexible pavement structure usually comprises more than one asphalt layer, with varying thicknesses and properties, in order to carry the traffic smoothly and safely. It is easy to characterize each asphalt layer with different tests to give a full description of that layer; however, the performance of the whole; asphalt structure needs to be properly understood. Typically, pavement analysis is carried out using multi-layer linear elastic assumptions, via equations and computer programs such as KENPAVE, BISAR, etc. These types of analysis give the response parameters including stress, strain, and deflection at any point under the wheel load. This paper aims to estimate the equivalent Resilient Modulus (MR) of the asphalt concrete

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Publication Date
Fri Jul 01 2016
Journal Name
Journal Of Engineering
FRACTURE PROPERTIES OF LOCAL ASPALT CONCRETE
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The local asphalt concrete fracture properties represented by the fracture energy, J-integral, and stress intensity factor are calculated from the results of the three point bending beam test made for pre notches beams specimens with deformation rate of 1.27 mm/min. The results revealed that the stress intensity factor has increased by more than 40% when decreasing the testing temperature 10˚C and increasing the notch depth from 5 to 30mm. The change of asphalt type and content have a limited effect of less than 6%.

 

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Publication Date
Fri Oct 01 2010
Journal Name
Iraqi Postgraduate Medical Journal
Frequency of genodermatoses among Iraqi patient
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HR Al-Hamami, AA Noaimi, MM Al-Waiz, AS Al-Kabraty, Iraqi Postgraduate Medical Journal, 2010 - Cited by 4

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Publication Date
Sun Oct 02 2016
Journal Name
Journal Of Educational And Psychological Researches
Aesthetic awareness among teachers of kindergarten
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All - Mighty Allah is beautiful and loves beauty and  Man is the only living  that is given by  the gift of Almighty Allah  the ability to awareness of beauty and the taste of  everything which recognized by him  around all aspects of life.

So the  children have more  ability  than others towards  feeling the  sense of beauty and the distinction between the beautiful and the ugly understanding , as they are attracted to the beauty , so we  should promote and encourage  their sense of beauty in future  the beauty in behavior , in psychology and in the community, as well.

This is definitely be done through all of

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