Preferred Language
Articles
/
OxeIW5MBVTCNdQwCc9I3
Impact of Plasma Focal Adhesion Kinase, Ephrin Receptor Type A4, and Adiponectin in Patients with Acute Myeloid Leukemia
...Show More Authors
Abstract<sec> <title>BACKGROUND:

Focal adhesion kinase (FAK), ephrin receptor type A4 (EphA4), and adiponectin (ADPN) are important indicators in inflammation, tumor growth, migration, and angiogenesis in some cancers. The predictive impact of their concentrations in acute myeloid leukemia (AML) patients to be identified remains. The research sought to explore the effect of FAK, EphA4, and ADPN as prognostic biomarkers, and their influence on patient survival, and to look for any potential correlation between their levels with hematological parameters in AML patients.

PATIENTS, MATERIALS, AND METHODS:

The study was carried out on 65 newly diagnosed adult de novo AML patients and 15 controls. Plasma levels were assayed by enzyme-linked immunosorbent assay at diagnosis. The overall survival (OS) was determined after 12 months.

RESULTS:

The FAK concentrations were significantly (P < 0.001) higher among AML patients than the controls. EphA4 level was insignificantly lower in AML patients than in control (P = 0.902), and insignificantly higher ADPN concentrations among AML patients than the control (P = 0.352). There were no significant differences between monocytic and nonmonocytic AML patients in FAK, EphA4, and ADPN levels. Regarding the OS, cases with lower than median levels of FAK were associated with a significant (P = 0.002) higher OS time in days, and cases with higher than median levels of EphA4 and ADPN had a significant (P = 0.007 and P = 0.039, respectively) higher OS time in days.

CONCLUSIONS:

FAK, EphA4, and ADPN can be used as noninvasive prognostic markers in AML patients with a possible role in AML pathogenesis, and resistance to chemotherapy.

Scopus Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Sat Jul 21 2018
Journal Name
Plant Archives
EXTRACTION, ANTIMICROBIALACTIVITYAND PHYTOCHEMICAL OF CLERODENDRUM VISCOSUM
...Show More Authors

Clerodendrum plant is believed to be very useful in many countries for treating various health disorders .“in this study was undertaken to assess antimicrobial activity of ethanol and aqueous extracts of clerodendrum plant”. Display my alcoholic extract higher inhibition of the aqueous extract all of the bacteria (Esherichia Coli , Pseudomonas aeruginosa, Bacillus subtilis). While the inhibition of the aqueous extract bacteria (Streptococcus, Shigelladysenteria) in higher alcoholic extract. However, the bacteria (Klebseillapneumoniae) did not shown any inhibition zone for both aqueous and alcoholic extracts. From the above results,“ it is concluded the antibacterial properties of Clerodendrum against life threatening pathogens”. So,

... Show More
Publication Date
Tue Mar 01 2022
Journal Name
Structures
Behavior of reinforced concrete tapered beams
...Show More Authors

Scopus (12)
Crossref (12)
Scopus Clarivate Crossref
Publication Date
Thu Aug 31 2017
Journal Name
Journal Of Engineering
Finite Element Analysis of UHPC Corbels
...Show More Authors

   Finite element method is the most widely numerical technique used in engineering field. Through the study of behavior of concrete material properties, various concrete constitutive laws  and failure criteria have been developed to model the behavior of concrete. A feature of the Finite Element program (ATENA) is used in this study to model the behavior of UHPC corbel under concentrated load only. The Finite Element (FE) model is followed by verification against experimental results. Some variable effects on the shear capacity of the UHPC corbels are also demonstrated in a parametric study. A proposed design equation of shear strength of UHPC corbel was presented and checked with numerical results.
 

View Publication Preview PDF
Publication Date
Sun Mar 26 2023
Journal Name
Wasit Journal Of Pure Sciences
Pure Graph of a Commutative Ring
...Show More Authors

A new definition of a graph called Pure graph of a ring denote Pur(R) was presented , where the vertices of the graph represent the elements of R such that there is an edge between the two vertices ???? and ???? if and only if ????=???????? ???????? ????=????????, denoted by pur(R) . In this work we studied some new properties of pur(R) finally we defined the complement of pur(R) and studied some of it is properties

View Publication Preview PDF
Crossref
Publication Date
Mon Mar 23 2020
Journal Name
Journal Of Engineering
Survey Study of Factional Order Controllers
...Show More Authors

This is a survey study that presents recent researches concerning factional controllers. It presents several types of fractional order controllers, which are extensions to their integer order counterparts. The fractional order PID controller has a dominant importance, so thirty-one paper are presented for this controller. The remaining types of controllers are presented according to the number of papers that handle them; they are fractional order sliding mode controller (nine papers), fuzzy fractional order sliding mode controller (five papers), fractional order lag-lead compensator (three papers), fractional order state feedback controller (three papers), fractional order fuzzy logic controller (three papers). Finally, several conclusions

... Show More
Publication Date
Tue Jul 01 1997
Journal Name
Polymer-plastics Technology And Engineering
Reverse Calculation of Pressure from Pseudopressure
...Show More Authors

View Publication
Scopus Clarivate Crossref
Publication Date
Tue Sep 18 2018
Journal Name
Kant
SOME METHODOLOGICAL OF LEARNING TENNIS STUDENTS
...Show More Authors

This study is due to insufficient development of the issues of initial training in tennis at youthful (student) age. Objective: development of a methodological and scientific-methodological base of students' tennis with current trends in tennis. Summing up the best practices of modern tennis, we came to the conclusion that the formation of the art of reflection backhands in teaching beginner students of sports specialization to achieve future success. In modern conditions in the development of Russian tennis student opens the possibility of using new technologies and programs. Using these approaches, we have developed a training program and tested students' tennis in the pedagogical experiment, which resulted in its effectiveness.

Publication Date
Tue Dec 01 2020
Journal Name
Baghdad Science Journal
A Generalization of t-Practical Numbers
...Show More Authors

This paper generalizes and improves the results of Margenstren, by proving that the number of -practical numbers  which is defined by   has a lower bound in terms of . This bound is more sharper than Mangenstern bound when  Further general results are given for the existence of -practical numbers, by proving that the interval contains a -practical for all

View Publication Preview PDF
Scopus (1)
Scopus Clarivate Crossref
Publication Date
Fri Feb 01 2019
Journal Name
Journal Of The College Of Education For Women
The Educational Ideology of John Dewey
...Show More Authors

The Educational Ideology of John Dewey

View Publication Preview PDF
Publication Date
Tue Jan 03 2023
Journal Name
College Of Islamic Sciences
The mechanism of managing religious difference
...Show More Authors

 

The mechanism of managing religious difference

God is the Lord of the worlds, forget them and their jinn, Arabs and non-Muslims, He is the Lord of Muslims and Lord of non-Muslims, as He created them male and female despite their differences in tongues and colors, so He created them according to their diversity and distinction in beliefs and religions.

 To prevent flare-ups due to differences, the Lord of the worlds set limits that he has forbidden to cross, and draw clear maps as mechanisms for managing religious differences and lifting psychological barriers between the different, so that they can coexist in peace and freedom, each adhering to his faith, and practicing the rituals of his religion.

... Show More
View Publication Preview PDF