Mannich base is a versatile compound that can be easily modified to introduce different functional groups, allowing for the creation diverse selection of items with varying features. Additionally, the Mannich reaction is a valuable tool in organic synthesis, due to the fact it provides an effortless and efficient approach for synthesizing C-N bonds. Overall, The Mannich base and even its derivatives are essential in many aspects of chemistry and its complexes are in the pharmaceutical industry. Studies have revealed that it shows good anti-cancer, anti-mycobacterial, remarkable anti-HIV, anti-tubercular, anti-convulsant, anti-fungal, antiviral, antitumor, cytotoxic activities and in industrial applications such as in the creation of polymers, surface activity agents, deter gents and resins. The presence of the basic Mannich sidechain has shown marked antimalarial, anti - inflammatory, analgesic and anti - microbial activities. These compounds have also been shown to inhibit corrosion, as well as antioxidant and reducing agents. This review article shows the definition, importance and different applications of Mannich base ligands with transitional metal. These complexes exhibit potent anti-microbial, antiviral, and anti-cancer activities, showcasing their potential in pharmaceutical research and drug development. Moreover, the luminescent properties of Mannich base metal complexes have been harnessed for applications in optoelectronics and sensing. Their tunable emission profiles make them suitable candidates for various sensing platforms and light-emitting devices Mannich base metal complexes.
Three-dimensional seismic reflection study was conducted for the Eastern
Baghdad oil field which is located in the middle part of Iraq within Al-Madaaen
province that belong to Baghdad governarate, South of Diyala River , this field
includes two southern parts (S1 and S2), the study area was about 781.905 km 2 for
the upper Cretaceous age, synthetic seismogram was generated from data of EB-5
and EB-1 wells. Saadi reflector was picked and identified to determine the Hartha
Formation. The seismic sections and time slice maps confirmed that the upper
Cretaceous age was affected by faults and the indicators of faults ended within
Hartha Formation and continue to the deeper formations with increasing intensity.
The
CD-nanosponges were prepared by crosslinking B-CD with diphenylcarbonate (DPC) using ultrasound assisted technique. 5-FU was incorporated with NS by freeze drying, and the phase solubility study, complexation efficiency (CE) entrapment efficiency were performed. Also, the particle morphology was studied using SEM and AFM. The in-vitro release of 5-FU from the prepared nanosponges was carried out in 0.1N HCl.
5-FU nanosponges particle size was in the nano size. The optimum formula showed a particle size of (405.46±30) nm, with a polydispersity index (PDI) (0.328±0.002) and a negative zeta potential (-18.75±1.8). Also the drug entrapment efficiency varied with the CD: DPC molar ratio from 15.6 % to 30%. The SEM an
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Breast tumors patients generally have more oxidative stress than normal females. This was clear from a highly significant elevation (P<0.05) in malondialdehyde level in RBCs, serum and tissue of all patients groups with breast cancer as compared with control group. In this study we had found that free radicals in malignant breast tumors were higher than benign tumors, therefore the MDA might be used as a marker for prognosis of the disease.
Objective: To evaluate the changes in the surface quality of irreversible hydrocolloid impression material
hydrogum following disinfection with 0.525% sodium hypochlorite, 0.2% Chlorehexidine Gluconate, and 4%
Povidone Iodine.
Methodology: Forty specimens of alginate impression materials hydrogum were fabricated according to the
ISO 1563 and were divided into four groups according to the method of solution dipping: group 1: Dip in
0.525% sodium hypochlorite, group 2: Dip in 0.2% chlorhexidine gluconate, Group 3: Dip in 4% Povidone Iodine,
Group 4: No treatment with any solution (control group). Then the specimens were poured in type II stone.
Surface detail was determined using a stainless steel block in accordance w
The study area is located at AL Jabal AL-Akhdar region North Eastern part of Libya. The study includes (23) fresh samples that are taken from Darnah limestone Formation, these samples were distributed on and covered about (210) km2. The porosities and permeabilities of these samples were determined. This study is important because this formation is considered as a good reservoir for hydrocarbon accumulation in other places in Libya.
The porosity was measured by three different methods namely by porosimeter (using core samples), thin sections and binocular microscope. The permeability are also measured by two methods, the first method was by Nitrogen method and the other is by Klinkenberg method. The instrument that used for measuring
In this part of programme , different bacterial isolates mainly Salmonella spp, Shigella spp and Escherichia coli were used for antagonism with Saccharomyces boulardii under different conditions . S.boulardii was grown under aerobic conditions and antagonized with young overnight nutrient broth cultures of test bacterial isolates and other kept in refrigerator for a week after full growth . Young cultures were more susceptible to antagonistic effect of yeast compared to old cultures and on isolates grown on solid medium for 24 hr. S.boulardii grown under aerobic and microaerobic conditions and antagonized with overnight broth cultures of test bacterial isolates , The results revealed that aerobic cultures of yeast had more inhibito
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Inflammatory bowel disease (IBD) a chronic inflammatory condition of the gastrointestinal tract characterized by alternating episodes of clinical relapse and remission (Wallace, 2014), with Crohn's disease (CD) and ulcerative colitis (UC) being the two primary subtypes (Souza, 2016). The present study was achieved in Baghdad teaching hospital from November 2021 to June 2022 to prove if the diagnostic marker of Crohn’s disease (CD) (IL-6, CRP and Calprotectin( are rises in saliva as in sera and if there are significant difference in the levels of those markers between the Crohn’s disease (CD)group and control group.
The recent study was measured the levels of C-reactive protein (CRP), Interleukin-6 (IL6
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Introduction: The present study was performed to evaluate the influence of a 1064 nm fiber laser on shear bond strength (SBS) at the interface of titanium and resin cement. Methods: Forty titanium discs of 6 mm × 3 mm (diameter and thickness respectively) were categorized into four groups (n=10): control group without any surface treatment and three groups treated with a fiber laser with 81 ns pulse duration, 30 kHz frequency, 10000 mm/s scanning speed, 0.05 mm spot size, and different average power values (3, 5 and 7 W) depending on the tested group. Titanium disc characterization was performed by the scanning electron microscope (SEM) and surface roughness tester. Phase analysis was achieved using an X-ray diffractometer (XRD). F
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In this paper, the effects of prey’s fear on the dynamics of the prey, predator, and scavenger system incorporating a prey refuge with the linear type of functional response were studied theoretically as well as numerically approach. The local and global stabilities of all possible equilibrium points are investigated. The persistence conditions of the model are established. the local bifurcation analysis around the equilibrium points, as well as the Hopf bifurcation near the positive equilibrium point, are discussed and analyzed. Finally, numerical simulations are carried out, and the obtained trajectories are drowned using the application of Matlab version (6) to explain our found analytical
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