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Effects of herbs–containing phytoestrogens on rat testis: A histological, histochemical and biochemical study

ABSTRACT: BACKGROUND: Estrogens has traditionally been known as the female hormone, but this idea has been challenged in early 1990’s and an essential physiological role for estrogen in male fertility was identified. Phytoestrogens are naturally occurring non-steroidal plant chemicals that can act like the female hormone estrogen. The herbs ( anise alfalfa and vervain ) chosen in this study contain phytoestrogens. OBJECTIVE: Previous studies demonstrated controversy of the effects of phytoestrogens on the rat testes .Hence, the present investigation was undertaken to investigate the influence of typical dose of herbs containing phytoestrogen on the rat testis. MATERIALS AND METHODS: Twenty-four apparently normal mature male rats were divided into four groups of 6 animals each. The first "control" group received only 4ml of distilled water as a placebo. The second group received 40mg/kg of anise seed; the third group received 53.3 mg/kg of dried herb of vervain and the fourth group received 400 mg /kg of alfalfa seeds. All experimental groups received the doses through orogastric tube daily for fourteen days. Testicular histology was evaluated by light and enzyme histochemistry. Plasma FSH and testosterone concentrations were taken to support our results. RESULTS: Histological examination of anise, alfalfa and vervain – treated groups showed an increase in the height of germinal epithelia. There was marked lipoprotein lipase activity in the whole of the interstitial tissue which is more in amount in experimental groups than that in control group. Acid phosphatase granules were infiltered the seminiferous epithelia mildly in control group , moderately in anise and vervain groups and markedly in alfalfa group. The number of interstitial cells showing marked acid phosphatase activity was higher in all experimental groups than that in control group. Alkaline phosphatase exhibited intense activity in the boundary tissue of the seminiferous tubules in testes of control and experimental groups but it appeared thicker in the latter. CONCLUSION: The low dose and short duration of treatment used in our study made these phytoestrogen – containing herbs to have a stimulatory effect on leydig cell steroidogenesis. This study also demonstrated that aniseed being the most potent of the three herbs followed by alfalfa in stimulating testosterone synthesis. This is possibly attributed to the coumarin constituent of aniseed and alfalfa. KEY WORDS: phytoestrogen-containing herbs, testis, acid phosphatase, alkaline phosphatase, lipoprotein lipase

Publication Date
Fri Jan 05 2018
Journal Name
International Journal Of Science And Research (ijsr)
Image Steganography Based on Discrete Wavelet Transform and Chaotic Map, IJSR, Call for Papers, Online Journal

'Steganography is the science of hiding information in the cover media', a force in the context of information sec, IJSR, Call for Papers, Online Journal

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Publication Date
Mon Jan 20 2020
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Genetic Algorithm and Particle Swarm Optimization Techniques for Solving Multi-Objectives on Single Machine Scheduling Problem

In this paper, two of the local search algorithms are used (genetic algorithm and particle swarm optimization), in scheduling number of products (n jobs) on a single machine to minimize a multi-objective function which is denoted as  (total completion time, total tardiness, total earliness and the total late work). A branch and bound (BAB) method is used for comparing the results for (n) jobs starting from (5-18). The results show that the two algorithms have found the optimal and near optimal solutions in an appropriate times.

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Publication Date
Fri Dec 01 2023
Journal Name
Iraqi Journal Of Physics
Polluted Water Sensor Based on Carbon Quantum Dots/Alq3 Using Drop Casting and Spin Coating Techniques

Water quality sensors have recently received a lot of attention due to their impact on human health. Due to their distinct features, environmental sensors are based on carbon quantum dots (CQDs). In this study, CQDs were prepared using the electro-chemical method, where the structural and optical properties were studied. These quantum dots were used in the environmental sensor application after mixing them with three different materials: CQDs, Alq3 polymer and CQDs and Alq3 solutions using two different methods: drop casting and spin coating, and depositing them on silicon. The sensitivity of the water pollutants was studied for each case of the prepared samples after measuring the change in resistance of the samples at a temperature of

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Publication Date
Sat Apr 01 2023
Journal Name
International Journal Of Electrical And Computer Engineering (ijece)
Flexible handover solution for vehicular ad-hoc networks based on software defined networking and fog computing

<p>Vehicular ad-hoc networks (VANET) suffer from dynamic network environment and topological instability that caused by high mobility feature and varying vehicles density. Emerging 5G mobile technologies offer new opportunities to design improved VANET architecture for future intelligent transportation system. However, current software defined networking (SDN) based handover schemes face poor handover performance in VANET environment with notable issues in connection establishment and ongoing communication sessions. These poor connectivity and inflexibility challenges appear at high vehicles speed and high data rate services. Therefore, this paper proposes a flexible handover solution for VANET networks by integrating SDN and

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Publication Date
Wed Apr 01 2020
Journal Name
Indian Journal Of Forensic Medicine & Toxicology
Hormonal and mineral imbalance effect on bone resorption in predialysis iraqi patients with chronic kidney disease

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Publication Date
Thu May 06 2010
Journal Name
Journal Of Engineering
A PROPOSED PROCEDURE FOR ANALYSING REINFORCED EMBANKMENTS

Publication Date
Thu Dec 01 2022
Journal Name
Journal Of Education For Pure Science- University Of Thi-qar
Dorsal Hand Vein Image Recognition: A Review

Subcutaneous vascularization has become a new solution for identification management over the past few years. Systems based on dorsal hand veins are particularly promising for high-security settings. The dorsal hand vein recognition system comprises the following steps: acquiring images from the database and preprocessing them, locating the region of interest, and extracting and recognizing information from the dorsal hand vein pattern. This paper reviewed several techniques for obtaining the dorsal hand vein area and identifying a person. Therefore, this study just provides a comprehensive review of existing previous theories. This model aims to offer the improvement in the accuracy rate of the system that was shown in previous studies and

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Publication Date
Tue Nov 26 2024
Journal Name
Philosophy Journal
Richard Rorty: Toward a Philosophy Without Mirrors

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Publication Date
Wed Jun 01 2011
Journal Name
Journal Of The College Of Basic Education
A Proposed Steganographic Method in Digital Media

WA Shukur, journal of the college of basic education, 2011 The aim of this research is designing and implementing proposed steganographic method. The proposed steganographic method don’t use a specific type of digital media as a cover but it can use all types of digital media such as audio, all types of images, video and all types of files as a cover with the same of security, accuracy and quality of original data, considering that the size of embedded data must be smaller than the size of a cover. The proposed steganographic method hides embedded data at digital media without any changing and affecting the quality of the cover data. This means, the difference rate between cover before hiding operation and stego is zero. The proposed steg

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Publication Date
Sun Feb 10 2019
Journal Name
Journal Of The College Of Education For Women
Building a Visual Test for Kindergartens’ children

The present research aimed to test the imagination of children, and may build sample consisted of (400) a baby and child, selected by random way of four Directorates (first Resafe, second Resafe ,first alkarkh , second alkarkh), in order to achieve the objective of research the tow researchers have a test of imagination and extract the virtual and honesty plants distinguish paragraphs and paragraphs and difficulty factor became the test consists of (32), statistical methods were used (Pearson correlation coefficient, coefficient of difficult passages, highlight paragraphs, correlation equation, an equation wrong Standard) the tow researchers have a number of recommendations and proposals.

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