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Effects of herbs–containing phytoestrogens on rat testis: A histological, histochemical and biochemical study

ABSTRACT: BACKGROUND: Estrogens has traditionally been known as the female hormone, but this idea has been challenged in early 1990’s and an essential physiological role for estrogen in male fertility was identified. Phytoestrogens are naturally occurring non-steroidal plant chemicals that can act like the female hormone estrogen. The herbs ( anise alfalfa and vervain ) chosen in this study contain phytoestrogens. OBJECTIVE: Previous studies demonstrated controversy of the effects of phytoestrogens on the rat testes .Hence, the present investigation was undertaken to investigate the influence of typical dose of herbs containing phytoestrogen on the rat testis. MATERIALS AND METHODS: Twenty-four apparently normal mature male rats were divided into four groups of 6 animals each. The first "control" group received only 4ml of distilled water as a placebo. The second group received 40mg/kg of anise seed; the third group received 53.3 mg/kg of dried herb of vervain and the fourth group received 400 mg /kg of alfalfa seeds. All experimental groups received the doses through orogastric tube daily for fourteen days. Testicular histology was evaluated by light and enzyme histochemistry. Plasma FSH and testosterone concentrations were taken to support our results. RESULTS: Histological examination of anise, alfalfa and vervain – treated groups showed an increase in the height of germinal epithelia. There was marked lipoprotein lipase activity in the whole of the interstitial tissue which is more in amount in experimental groups than that in control group. Acid phosphatase granules were infiltered the seminiferous epithelia mildly in control group , moderately in anise and vervain groups and markedly in alfalfa group. The number of interstitial cells showing marked acid phosphatase activity was higher in all experimental groups than that in control group. Alkaline phosphatase exhibited intense activity in the boundary tissue of the seminiferous tubules in testes of control and experimental groups but it appeared thicker in the latter. CONCLUSION: The low dose and short duration of treatment used in our study made these phytoestrogen – containing herbs to have a stimulatory effect on leydig cell steroidogenesis. This study also demonstrated that aniseed being the most potent of the three herbs followed by alfalfa in stimulating testosterone synthesis. This is possibly attributed to the coumarin constituent of aniseed and alfalfa. KEY WORDS: phytoestrogen-containing herbs, testis, acid phosphatase, alkaline phosphatase, lipoprotein lipase

Publication Date
Mon May 21 2007
Journal Name
Journal Of Planner And Development
Towards a decentralized planning policy in Iraq

Iraq is changing from the centralized system of governance to the decentralized system, which assumes devolution of more authorities to the local governments of Iraqi provinces and cities. This puts a responsibility on the academics to produce more research work on the best framework for this change, to ensure the best results. The main objective of this research is to suggest a policy for the decentralized transformation in domain of Urban and Regional Planning in Iraq. A suggested program for the transformation is involved in the paper as well, with analysis for the new relationships between different levels of planning authorities depending on democracy. In addition, a description for planning process flows from bottom to top.

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Publication Date
Wed Dec 15 2021
Journal Name
Arab World English Journal
Aggressive Language in Literature: A Pragmatic Approach

Aggression is a negative form of an anti-social behavior. It is produced because of a particular reason, desire, want, need, or due to the psychological state of the aggressor. It injures others physically or psychologically. Aggressive behaviors in human interactions cause discomfort and disharmony among interlocutors. The paper aims to identify how aggressive language manifests itself in the data under scrutiny in terms of the pragmatic paradigm. Two British literary works are the data; namely, Look Back in Anger by John Osborne (1956), and The Birthday Party by Harold Pinter (1957). This paper endeavors to answer the question of how aggressive language is represented in literature pragmatically? It is hoped to be significant to

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Publication Date
Sat Jan 30 2021
Journal Name
Iraqi Journal Of Science
A Metaheuristic Approach to the C1S Problem

Given a binary matrix, finding the maximum set of columns such that the resulting submatrix has the Consecutive Ones Property (C1P) is called the Consecutive Ones Submatrix (C1S) problem. There are solution approaches for it, but there is also a room for improvement. Moreover, most of the studies of the problem use exact solution methods. We propose an evolutionary approach to solve the problem. We also suggest a related problem to C1S, which is the Consecutive Blocks Minimization (CBM). The algorithm is then performed on real-world and randomly generated matrices of the set covering type.  

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Publication Date
Mon Nov 19 2018
Journal Name
Al–bahith Al–a'alami
A Proposed Vision for Editing News Forms

This research deals with a very important subject as it tries to change the theoretical and scientific heritage and some professional rules adopted in the newsroom. Most media students have difficulties in writing news for press correctly. The researcher tries to identify the compatibility of what is published in local news agencies with professional and academic standards.
The research finds detailed editorial rules for a number of news formats which will play an important role in writing news for press easily, especially for the beginners and newcomers. Also, it discovers a new fact denying the beliefs of some researchers and writers in not having news conclusion in news edited according to the inverted pyramid pattern.
The re

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Publication Date
Sat Jul 31 2021
Journal Name
Iraqi Journal Of Science
Chaos in a Hybrid Food Chain Model

In this paper, chaotic and periodic dynamics in a hybrid food chain system with Holling type IV and Lotka-Volterra responses are discussed. The system is observed to be dissipative. The global stability of the equilibrium points is analyzed using Routh-Hurwitz criterion and Lyapunov direct method. Chaos phenomena is characterized by attractors and bifurcation diagram. The effect of the controlling parameter of the model is investigated theoretically and numerically.

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Publication Date
Wed Jan 02 2013
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Rotavirus infection as a cause watery diarrhea

Summary
Background: Rotavirus infection is the most commoncause of watery viral diarrhea in children younger than 5 years of age; it is a major cause of childhood morbidity and mortality.
Objective:The aim of the study is todetermine the clinical picture, age distribution of patients with rotavirus infection and their maternal educational background.
Patients &methods: A total of 202 patients suffering from diarrhea were included in this study, over 6 months period( from 1stof March 2011to 30th of August 2011),in Children Welfare Teaching hospital. History and physical examinationwere carried out, anthropometrics measures were done and plotted on Centers for Disease Control& World Health Organization charts to determine

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Publication Date
Tue Mar 30 2021
Journal Name
Baghdad Science Journal
User-Oriented Preference Toward a Recommender System

            Nowadays, it is convenient for us to use a search engine to get our needed information. But sometimes it will misunderstand the information because of the different media reports. The Recommender System (RS) is popular to use for every business since it can provide information for users that will attract more revenues for companies. But also, sometimes the system will recommend unneeded information for users. Because of this, this paper provided an architecture of a recommender system that could base on user-oriented preference. This system is called UOP-RS. To make the UOP-RS significantly, this paper focused on movie theatre information and collect the movie database from the IMDb website that provides informatio

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Publication Date
Sun Jul 03 2011
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Type II- Pleuropulmonary Blastoma: A case report

Pleuropulmonary blastoma is a rare and aggressive neoplasm typically presents in young children, younger than 5 years, as a pulmonary and/or pleural-based tumor. We reported a case of type-II pleuropulmonary blastoma (PPB) in an 8 month old infant who presented to Al-Khansa'a Maternity Hospital in Western Mosul with a history of repeated attacks of shortness of breath and signs of pulmonary infection unresponsive to treatment. A bronchoscopic examination showed a mass involved and obstructed the orifice of the main bronchial tree of the right upper lung lobe. A thoracotomy was performed; tumor involved the right upper lung lobe, the covering pleural surface and invading the mediastinal structures. Right

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Publication Date
Wed Jan 01 2020
Journal Name
Annals Of Tropical Medicine And Public Health
Dithiocarbamates derivatives as anticancer agents: A Review

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Publication Date
Wed Sep 07 2022
Journal Name
2022 Iraqi International Conference On Communication And Information Technologies (iiccit)
Vehicular Ad-hoc Network (VANET) – A Review

This paper explores VANET topics: architecture, characteristics, security, routing protocols, applications, simulators, and 5G integration. We update, edit, and summarize some of the published data as we analyze each notion. For ease of comprehension and clarity, we give part of the data as tables and figures. This survey also raises issues for potential future research topics, such as how to integrate VANET with a 5G cellular network and how to use trust mechanisms to enhance security, scalability, effectiveness, and other VANET features and services. In short, this review may aid academics and developers in choosing the key VANET characteristics for their objectives in a single document.

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