وفاء صبري ماهود
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Dr. Wafaa SAbri Mahood
PhD
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assistant professor
College of Education for Pure Sciences (Ibn Al-Haitham)
,
Deparment of Biology
[email protected]
Publication Date
Thu Jun 08 2017
Detection of BRAF Gene in Some Iraqi Bowel Inflammation and Colorectal Cancer Patients
The impacts of the inflammatory process on neoplasia development were observed in many cancer, it has a great role in the etiology, development and progression of invasive colorectal tumors. This study was designed to investigate the BRAF mutation and assist the clinicopathological parameter in some Iraqi bowel inflammation and colorectal cancer patients. Thirty patients were enrolled in this study (15 suffering bowel inflammation and 15 having colorectal cancer). BRAF gene was screened for the presence of mutations using PCR technique and direct sequencing. .The results revealed no BRAF mutation in position 1799 for exon fifteen in both samples of bowel inflammation and colorectal cancer. These results were confirmed previous arti
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