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Parkinson’s disease (PD) consider as a progressive ageing neurodegenerative disease,
Parkinson’s consider as a heterogenous disease, with mainly initiate through correlation between genetic
and epigenetic by inducing of different factors on some related genes, these factors like (environmental,
toxicants, nutrition, heavy metals, pesticides, some drugs) and also(trauma on head ,strokes) in addition to
unknown reasons which cause an idiopathic PD .Current study aims to focusing on specific related PD
gene called SNCA by single nucleotides polymorphism (rs2619363) as a risk factor for PD initiation
disease in PD patients in addition to study the effect of polymorphisms on random Iraqi patients with
different gastrointestinal
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