Despite not being digested, trace elements and/or heavy metals are important for the activity of enzymes, physiological processes, and homeostasis. If certain trace elements are present in excess, they can have harmful effects and pose major health hazards. Objective: The aims to examine the connection between serum zinc, copper levels, and the Cu/Zn ratio, and several anthropometric parameters, including an index of body mass and the waist-hip ratio. In our study, we used atomic absorption spectrometry (AAS) to measure serum levels of copper (Cu) and zinc (Zn) in 60 individuals, 30 patients with kidney cancer and 30 healthy controls. We assessed serum uric acid, creatinine, and urea using the semi-auto analyzer BA-88A (Korea). The results revealed a highly significant in the level of serum Cu, Zn and Cu/Zn ratio when compared with control, additionally high significant elevation in serum uric acid, creatinine and urea when compared with control. The result also indicates a prevalence of body mass index (BMI) and waist-hip-ratio (WHR) in patients with kidney cancer when compared with control. Our study compares blood levels of copper (Cu) and zinc (Zn) in kidney cancer patients to those in healthy controls. We aim to investigate any differences in the prevalence of these trace elements between the two groups, additionally of that a good relationship between BMI and WHR with serum Cu and Zn in the patient with kidney cancer. Current data reveal a significant prevalence of altered levels of copper (Cu), zinc (Zn), and the Cu/Zn ratio in patients with kidney cancer