أختبرت في هذه الدراسه حساسيه اختبار فرط الحساسية المتأخر وعلاقته ببعض معايير الخمج باللشمانيا في مجموعتين من حيوانات الهامستر المحقونه و كالآتي : حقنت المجموعة الأولى بطفيلي اللشمانيا الأحشائيه الحيه بينما حقنت المجموعةالثانية بلقاح عالق اللشمانيا الجلديه المقتولة بالحرارة . اظهرت المجموعه الثانيه اعلى معدل في تفاعل فرط الحساسية المتأخر(1.5 ±0.23ملم) , واقل المعدلات في كل من معامل الطحال (2.02±0.15) , طول الطحال (28.3±0.25 ملم) , معامل الكبد (4.47±0.24) واعداد الطفيليات في الطحال (1.8±0.02) مليون طفيلي, بينما أظهرت المجموعه الأولى اقل معدل في تفاعل فرط الحساسية المتأخر(1.01 ±0.08ملم) , واعلى المعدلات في كل من نسبة تضخم الطحال (2.45 ±0.15), طول الطحال (33±0.01 ملم) , معامل الكبد (5.60±0.19) واعداد الطفيليات في الطحال (11±0.5مليون طفيلي). يمكن ان تكون هذه النتائج دليلاً على وجود علاقه عكسيه بين الأستجابه لأختبار فرط الحساسيه المتأخر و بعض معايير شدة الخمج التجريبي باللشمانيا في حيوانات الهامستر الذهبي.
اختبار فرط الحساسية المتأخر وعلاقتة بشدة الخمج لمستضدين مختلفين لجنس اللشمانيا
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Publication Date
Wed Nov 30 2016
Journal Name
International Business Management
ESTIMATE OF THE MULTIPLIER EFFECT OF THE MONETARY AND FISCAL POLICY ON NON-OIL GROSS DOMESTIC PRODUCT IN THE IRAQI ECONOMY FOR THE PERIOD OF 1990-2014
The monetary policy is a vital method used in implementing monetary stability through: the management of income and adjustment of the price (monetary targets) in order to promote stability and growth of real output (non-cash goals)
the tool of interest rate and direct investment guides or movement towards the desired destination
and supervisory instruments of monetary policy in both quantitative and qualitative. The latter is very important as a standard compass to investigate the purposes of the movement monetary policy in the economy. The public and businesses were given monetary policy signals by those tools. In fiscal policy
there are specific techniques to follow to do the spending and collection of revenue. This is done in order to actualize the adopted goals by the state and the relative closeness between monetary policy and fiscal policy objectives that requires relationship between two policies. Also
in order to achieve the goal of stability and promote economic growth within the tax multiplier. Multiplier of government spending is aiming at the goal of stability automatically and the allocation or distribution of economic stability through a basic introduction of the aim and objective of allocating resources to the required fields. In this vein
the objectives of the fiscal policy can be brought up spontaneously with the provisions of side and control effects which are in consonant with the outcome received in terms of economic cycle. The research showed that the impact of monetary policy in Iraq is insignificant on non-oil gross domestic product through a multiplier of monetary policy (K) and the flexibility of non-oil gross domestic product for money supply (E). Similarly
the impact of fiscal policy on non-oil gross domestic product through the fiscal policy multiplier (K) and the flexibility of non-oil gross domestic product for the government to spend are insignificant
The monetary policy is a vital method used in implementing monetary stability through: the management of income and adjustment of the price (monetary targets) in order to promote stability and growth of real output (non-cash goals); the tool of interest rate and direct investment guides or movement towards the desired destination; and supervisory instruments of monetary policy in both quantitative and qualitative. The latter is very important as a standard compass to investigate the purposes of the movement monetary policy in the economy. The public and businesses were given monetary policy signals by those tools. In fiscal policy, there are specific techniques to follow to do the spending and collection of revenue. This is done in order to
... Show MorePublication Date
Tue Mar 01 2022
Journal Name
Iraqi Journal Of Agricultural Sciences
CORRELATION OF TMPRSS2-ERG GENE FUSION STATUS WITH CLINICOPATHOLOGICAL CHARACTERISTICS IN PROSTATE CANCER OF IRAQI PATIENTS
The aim of this study was to establish the existence and interaction of TMPRSS2 – ERG gene fusion status with clinicopathological features of prostate cancer patients. This research consisted of 123 embedded formalin-fixed tissues obtained from the prostate tumor patients. The above gene fusion is detected through the technique of fluorescent in situ hybridization (FISH) by means of a triple color probe. Seven samples have not been scored due to technical difficulties and 46 patients have fusion (39.6%)
while the remaining (70) have not been seen with fusion. Of the 46 fusion-positive
17 (36%) were caused by ERG-translocation
of the other 29 (63%) were caused by the interstitial segment deletion between the two genes due to their sequential position. In order to find a substantial correlation between 116 patients (fusion took place in 46 and non-fusion in 70) with clinicopathological features
the following findings were calculated: Our findings recorded non-significant correlation at age
BMI and tumor size at which (P-value >0.05).While results showed significant association with: pathological T stage (P value = 0.011)
Gleason score (P value = 0.002)
perineural invasion (P value = 0.047) and PSA (P value = 0.033). The clinicopathological features which had a considerable correlation with fusion status are very important as they aid the doctors in prognosis and treatment of such tumor.
Publication Date
Sat Sep 01 2018
Journal Name
Polyhedron
Novel dichloro (bis {2-[1-(4-methylphenyl)-1H-1, 2, 3-triazol-4-yl-κN3] pyridine-κN}) metal (II) coordination compounds of seven transition metals (Mn, Fe, Co, Ni, Cu, Zn and Cd)
The 1
3-dipolar cycloaddition “click” reaction between an azide and an alkyne to give a 1
2
3-triazole was reported by Huisgen in 1961 [1]. In 2002 the Copper(I)-catalyzed Azide-Alkyne Cycloaddition (CuAAC) to prepare a 1
2
3-triazole was reported [2]
[3]. The existence of relatively basic nitrogen atoms in the 1
2
3-triazole rings
and the possibility of introducing additional donor groups in the substituents (Fig. 1)
made the CuAAC “click” reaction an attractive method to prepare differently substituted 1
2
3-triazoles. These compounds have been used as ligands to coordinate to various metal ions that display a range of applications such as in electrochemical and photochemical studies
in supramolecular chemistry
magnetism
metal-ion sensing and catalysis [4]. The reasons for the success of the “click” reaction
is that it is easy to carry out and is widely applicable. It is not affected by a variety of functional groups
and can be carried out with a variety of Cu(I) catalysts and solvents
including aqueous conditions. The Cu(I) catalysts overcome the high activation energy barrier of the non-catalyzed Huisgen reaction by changing the mechanism of the reaction. A large variety of copper catalysts can be used for the CuAAC reaction
on condition that the maximum concentration of Cu(I) species is generated during the reaction. The pre-catalyst can be a Cu(II) salt (usually CuSO4) together with a reducing agent (often sodium ascorbate) or a Cu(I) compound in the presence of a base or amine ligand and a reducing agent to prevent oxidation to Cu(II). Some strong oxidising cupric salts or complexes such as Cu(OAc)2 also work. The solvent is very flexible from organic to aqueous
with the most commonly used combination water + an alcohol (t-BuOH
MeOH or EtOH). The key role of the solvent or solvent mixture is to solubilize the substrates and Cu(I) catalyst in order to ensure rapid reactions. Such aqueous conditions are very useful for biochemical conjugations
as well as for organic syntheses.
We recently reported on the synthesis of a series of differently substituted 1
2
3-triazole chromophores
the substituted 2-(1-phenyl-1H-1
2
3-triazol-4-yl)pyridine ligands [5]
see Fig. 2 middle
with substituents R = H (L1)
CH3 (L2)
OCH3 (L3)
COOH
F
Cl
CN
CF3
O(CH2)3CH3 and N(CH3)2. These versatile ligands were found to coordinate to various first row transition metals
such as manganese
cobalt and nickel [6]. Here we extend the series to include more first row transition metal(II) coordination compounds
iron
copper and zinc
as well as a second row transition metal(II) coordination compound
cadmium
containing the 2-(1-(4-methyl-phenyl)-1H-1
2
3-triazol-1-yl)pyridine chromophore (Fig. 2 right with R = CH3). This series of seven novel coordination compounds is the first series of pyridyl-triazole based transition metal coordination compounds where seven different transition metals are coordinated to the same 1
2
3-triazole chromophore
namely 2-(1-(4-methyl-phenyl)-1H-1
2
3-triazol-1-yl)pyridine.