Background: Hybrid diabetes (or double diabetes, DD) occur when the patient which exhibits characteristics that combine type 1 diabetes (T1DM) and type 2 diabetes (T2DM). Formerly epidemiological studies found that quarter of people with T1D also had the metabolic syndrome. Subfatin, Also called cometin, it is a small (~27kDa) cytokine secreted by protein encoded by a gene called METRNL (simeler of meteorin). is much expressed in skin in the mucosal tissues and activated macrophages. Subfatin has also been described as a hormone that effected in some diseases such as metabolic diseases (including dyslipidemia), type 2 diabetes and obesity. Objectives: The current study objective is evaluating the subfatin in the blood serum of double diabetes patients to find predictive significance of diagnosis for this disease. Subjects and methods: Eighty individuals were studied , divided them into two groups . Forty patients with double diabetes represented the first group (G1), and the second group (G2), which represented the control group, consisted of (40) individuals, and the range ages of the study were (18-60)years. Whole blood was used to determine HbA1c. Samples were centrifuged, and the obtained serum was used to evaluate other biochemical markers. The technique used to determine the level of subfatin in the blood was a quantitative sandwich enzyme-linked immunosorbent assay (ELISA). Results: A significant increase shown by this study in the serum levels of subfatin in (DD) patients (n = 40) compared with control subjects (n = 40) (p value < 0.05). The ROC curves analysis for serum subfatin level when used as test for diagnosis subjects into of double diabetes cases (G1) and control group (G2), showed the AUC ( area under curve) for serum of subfatin was (1.000) have interval of confidence (95% ) and both lower and upper bound was (1.000). Conclusions: serum subfatin level could be a used as a novel biomarker of double diabetes (DD) and may contribute to the early diagnosis of diabetes.
The research aims to demonstrate the quality of the auditor’s report by analyzing a number of models represented by the auditor’s report based on the Iraqi audit evidence and the auditor’s report in light of the application of international auditing standards for the report and the auditor’s report in light of the application of the International Auditing Standard 701, in addition to explaining the impact of applying the International Auditing Standard 701. International Auditing 701 in enhancing the quality of the auditor's report, and in order to reach these goals, a comparison was made on international experiences before and after the application of the standard in addition to the results of the questionnaire distribut
... Show MoreBackground: Fractures of the humeral shaft
accounting for approximately 3% of all
fractures. There is a wide array of good
options for their treatment and controversy
over the best methods. Although good
techniques of osteosynthesis are available, the
aim of this article is toemphasize on the benefit
and good outcome of conservative treatment
for properly selected cases to decrease the cost
and avoid the complications of surgery.
Ovarian cystic lesions are one of the most common pathologic disorders in gynecology and a common reason for surgery. The purpose of the study was to determine the histopathologic characteristics of benign cystic ovarian lesions and their correlation to age, type, laterality, locularity, and size of ovarian cystic lesions. This is a retrospective study carried out on 100 cases from the archive in the Imam Kadhimian medical city and the educational laboratories of Baghdad medical city, out of 100 patients, the most common age group that underwent cystectomy was 20-40 years old. The vast majority of the cysts were non-neoplastic (67%) while the neoplastic cysts occupy 33% of all cysts. The most common non-neoplastic cyst was cor
... Show MoreBackground: Endometrial Cancer (EC) is the malignant tumor originating from endometrium cell (lining of the uterus). EC incidence and mortality have increased in recent years. Routinely used methods for EC diagnosis and treatment are histopathological tissue culture after surgery and postoperative radiotherapy, however there is still not enough efficient treatment for recurrence or progression of this disease. So, there is a critical need for further EC identification by new biological ways for the prognostic diagnosis of it. Objective: This study aimed to look for ways by which could help in diagnosis of EC before the hysterectomy. Materials and Methods: 55 patients with EC and 57 healthy women were involved in this study (up to 45 years)
... Show MoreThis study was designed to determine the correlation between Y chromosome azoospermia factor (AZF) subregions microdeletions and oligozoospermia in infertile men. Subjects included 50 infertile men with oligozoospermia who had been referred to the Fertility Center and infertility treatment in Kamal Al-Samarrai Hospital\Baghdad health office-Iraq. DNA was extracted from blood samples. Polymerase chain reaction (PCR) amplification of 3 loci spanning the AZFa, AZFb and AZFc subregions of the Y chromosome using sY84, sY127 and sY254 and were performed. The frequency of deletions involving AZFa subregion of the Y-chromosome was found in twelve of the patients (24%) in oligozoospermic infertile Iraqi men. While the other subregion (AZFb and AZ
... Show MoreOral carcinoma is the 6th most common cancer in the world. MicroRNAs are small non-coding single stranded RNAs. They have been shown to be capable of altering mRNA expression; thus some are oncogenic or tumor suppressive in nature. The salivary microRNA-31 has been proposed as a sensitive marker for oral malignancy since it was abundant in saliva more than in plasma. A total of 55 whole saliva samples were collected from 35 cases diagnosed with OC their ages and gender matched with 20 healthy subjects. TaqManq RT-PCR was performed for RNA samples. Mean age was 52.23+13.73 years in cases (range:17-70 years) with male predominance represented 69%. Risk of smoking and alcoholism was highly significant. The median fold change of miR-31 was sign
... Show MoreBackground : The aim of this work is to study the clinical features and causative fungi of tinea pedis in diabetic and non-diabetic patients. Result : Tinea pedis was estimated to be the second most common skin disease in the United States, after acne. Up to 15% of the U.S., population may have tinea pedis. Across Europe and East Asia, prevalence rates reach 20 %. Methods: The Complete history taking regarding: age, sex, occupation, residency, history of diabetes and diabetic profile (fasting blood sugar and post prandial).and Clinical examination of the feet Aim of the study : The aim of this work was to study the clinical features and causative fungi of tinea pedis in diabetic and non-diabetic patients Conclusion : Tinea pedis is more
... Show MoreBackground: Epilepsy is a common neurological disorder of incidence rate 1-2%. Genetic, congenital, developmental, tumors, head trauma and central nervous system infections maybe the cause of epilepsy. This study aimed to determine the prevalence of stomatitis, xerostomia and taste disorder among patients taking carbamazepine or sodium valproate and to make salivary analysis for IgA, cystatin c and salivary flow rate. Material and method:This study performed in al- Yarmuk teaching hospital in Baghdad, Samples consist of (70) epileptics half of them treated with carbamazepine and other half treated with sodium valproate, and (18) healthy control group of both genders and with different ages to detect the prevalence of oral manifestations, s
... Show MoreBackground: Fractures of the humeral shaft accounting for approximately 3% of all fractures. There is a wide array of good options for their treatment and controversy over the best methods. Although good techniques of osteosynthesis are available, the aim of this article is toemphasize on the benefit and good outcome of conservative treatment for properly selected cases to decrease the cost and avoid the complications of surgery. Method : During the period from February 2011 to June 2012 fifty-five fractures of humeral shaft were treated at orthopedicdepartment in the ALKindyteaching hospital. 22 fractures considered suitable for the study. The patients treatedconservatively by using the‘U’ shaped coaptation slab. Then we shift to POP c
... Show MoreABSTRACT The present study was conducted to determine the mode of presentation of hypothyroidism in pediatric patients and the effects of timing of diagnosis and therapy on the patient’s outcome. The study involved review and evaluation of the medical records of 41 registered patients in the Endocrine clinic of Children Welfare Teaching Hospital in Baghdad during the period from January 1991 to July 2007. Forty one patients included in this study. Twenty four (58.5%) were males and17 (41.4%) were females with a male to female ratio of 1.4:1, their age range is 40 days to12.3 years. The majority of the studied patients were infants 19(47%). The most commonly observed presenting features were growth retardation and short stature. The best t
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