Drug loading
Drug release
Controlled release
Kinetic release
Surface functionalization
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In this work, mesoporous silica SBA-15 was prepared and functionalized with amine groups (i.e., NH2)
to form NH2/SBA-15. The curcumin (CUR) was encapsulated into the surface and pore of NH2/SBA-15 to
create CUR@NH2/SBA-15 as an efficient carrier in drug delivery systems (DDSs). The three samples (i.e.,
SBA-15, NH2/SBA-15, and CUR@NH2/SBA-15) were characterized. The study investigated the effect of the
carrier dose, initial CUR concentration, pH, and contact time on the CUR loading efficiency (DLE%) via
adsorption. The best DLE% for the SBA-15 and NH2/SBA-15 were found to be 45% and 89.7%, respectively.
The Langmuir isotherm had a greater correlation coefficient (R2) of 0.998 for SBA-15. A pseudo-secondorder kinetic model seemed to fit well
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