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The aim of this study is to find a relationship between oxidative stress and adiponectin in
Iraqi patients with acromegaly. The present study included 30 patients with acromegaly
disease attending at Al-Yarmuk teaching hospital , and 30 healthy individuals as a control
group.The two groups with ages ranging (30-55) years. The results revealed a highly
significant elevation in all parameters (GH,IGF-1 , adiponectin , malondialdehyde , and
peroxynitrite ) levels in sera of patients when compared with healthy control .It can be
concluded that oxidative stress (malondialdehyde and peroxynitrite ) may be valuable in
detecting of endocrine diseases like acromegaly .