Recently, some prostate cancer patients have acquired resistance to the second -generation drugs (anzalutamide and apalutamide) prescribed for the treatment of this disease due to the emergence of the F876L mutation, which represents a challenge to modern medicine. In this study, a new series of 2-thiohydantoin derivatives were prepared through the reaction of different derivatives of maleimide (1c-4c) with isothiocyanate derivatives. The prepared compounds were diagnosed using FT-IR,¹H-NMR ,¹³C-NMR, Mass spectra. The prepared series compounds has been studied against prostate cancer cells. The MTT assay was used to determine the activity of the prepared compounds against prostate cancer cells. The da

فسيفساء قبة الصخرة دراسة تحليلية

Intelligence is the production of nervous system function and it's contents memory and creative thinking and understanding and other processes. It's a general cognitive ability and it's a concept. It's essential for good judgment and reasoning, there's an argument about definition of intelligence, is it one ability or multiple abilities. Multiple intelligences theory presented by (Gardner 1983) view intelligence as composing from six types of intelligences: (1) linguistic. (2) mathematical. (3) visual – spatial. (4) musical. (5) bodily – kinesthetic. (6) personal. Present research has reached to several conclusions. Most important one is that multiple intelligences theory is based on the conception of distinct varieties of intelligen

This research examines the electronic check slip of an educational doctrinal study, in terms of explaining the truth of the electronic check and the legal organization of it and the way it is handled, and then devising the jurisprudence related to it.

After this trip start to get interesting conclusion, conclusion and maintenance station,
the conclusion, where we summarize the most important findings:
1. We found that the triads are the conversations that will be assigned in three narrators
between the workbook and the Prophet.
2. The number of triangles is the Imam recaps (15) recently, and all true only recently one
well in the Book of Rites and the modern were weak in the book authorization and the Book of
Virtues of the Quran.
3. Triads varied in the ways of drama at the gates of Islamic jurisprudence, he may talk and
one each from the Book of purity and prayer, fasting, marriage and the tortillas and the virtues
of the Quran, and has had three conversat

Judicial jurisprudence is one of the important legal solutions to address the shortcomings of legislation. Throughout its long history, human societies have known many cases in which the judge finds himself facing a legislative vacuum in addition to civil legal texts that are difficult for the judge to implement due to ambiguity or contradiction, which requires diligence. To rule on resolving disputes before him in order not to deny justice, but the judge in his jurisprudence was not absolute, but rather bound by certain controls represented by observing the wisdom of legislation on the one hand and taking into account the nature of the texts on the other side, and from here this research came to shed light on the jurisprudence and its cont

 In the research I dealt with the form of the preference verb, as well as the elements of the preference noun and its states in its abstraction from the and addition and its conjugation with (the) and its addition to the negation and knowledge. It is (good, evil, and love) omitting the hamza in it.

The most influential theory of ‘Politeness’ was formulated in 1978 and revised in 1987 by Brown and Levinson. ‘Politeness’, which represents the interlocutors’ desire to be pleasant to each other through a positive manner of addressing, was claimed to be a universal phenomenon. The gist of the theory is the intention to mitigate ‘Face’ threats carried by certain ‘Face’ threatening acts towards others.

            ‘Politeness Theory’ is based on the concept that interlocutors have ‘Face’ (i.e., self and public – image) which they consciously project, try to protect and to preserve. The theory holds that various politeness strategies are used to prot

The divorce is one of the important problem that prominence in Iraq it needs a remedy speedily .

This problem appears specially at the war of 2003 , it is effected on culture and it trances through communications tools , internet and satellite .

Supreme judicial council recorded about (41536) divorced cases , whereas the rate of this number arise to (87.530) through 2012 , in the same time the Iraqi courts recorded about 20%-30% of wedding cases .

The two researchers focused in their study on the concept of Alienation as a basic variable through its enhancing on the psychological health for divorces , in which they take this sense to connect it with their shortage that reflect negatively on their psychological and

Find cares studying the aesthetics of environmental art, one of the topics that is one of the problems of the aesthetic side in the arts of postmodernism, so this research came as an attempt to get to know the aesthetic concepts of environmental art that can be learned from functional testing in the formation of the post-modern control. The research involved four chapters: The first chapter discusses the general framework of the research methodology, as it was displayed in itThe research problem and its importance and define its objective to identify the aesthetics of environmental art at the level of the body, meaning, the receiver .ozlk in Iraq and America as the spatial limits of the time limits are period stretching from 1970 to 2006