Silymarin, a flavolignans from seeds of ‘milk thistle’ “Silybum marianum” has been widely used from ancient times because of its excellent hepatoprotective action. It has been used clinically to treat liver disorders including acute and chronic viral hepatitis, toxin/drug-induced hepatitis and cirrhosis and alcoholic liver disease. The efficacy and dose-response effect of silymarin (125, 250 and 500 mg/kg) were assessed using egg albumin-induced paw edema in rats as a model of acute inflammation. In this model, 56 rats were used and allocated into 7 subgroups each containing 8 rats. All treatments were given intraperitonealy 30 minutes before induction of inflammation by egg albumin and then the increase

In this paper, a four species mathematical models involving different types of ecological interactions is proposed and analyzed. Holling type – II functional response is a doubted to describes the behavior of predation. The existence, uniqueness and boundedness of the solution are discussed. The existences and the stability analysis of all possible equilibrium points are studied. suitable Lyapunov functions are used to study the global dynamics of the system. Numerical simulations are also carried out to investigate the influence of certain parameters on the dynamical behavior of the model, to support the analytical results of the model.

     The work in this paper focuses on solving numerically and analytically a  nonlinear social epidemic model that represents an initial value problem  of ordinary differential equations. A recent moking habit model from Spain is applied and studied here. The accuracy and convergence of the numerical and approximation results are investigated for various methods; for example, Adomian decomposition, variation iteration, Finite difference and Runge-Kutta. The discussion of the present results has been tabulated and graphed. Finally, the comparison between the analytic and numerical solutions from the period 2006-2009 has been obtained by absolute and difference measure error.

This study aims to numerically simulate the flow of the salt wedge by using computational fluid dynamics, CFD. The accuracy of the numerical simulation model was assessed against published laboratory data. Twelve CFD model runs were conducted under the same laboratory conditions. The results showed that the propagation of the salt wedge is inversely proportional to the applied freshwater discharge and the bed slope of the flume.  The maximum propagation is obtained at the lowest discharge value and the minimum slope of the flume. The comparison between the published laboratory results and numerical simulation shows a good agreement. The range of the relative error varies between 0 and 16% with an average of 2% and a roo

Finding communities of connected individuals in complex networks is challenging, yet crucial for understanding different real-world societies and their interactions. Recently attention has turned to discover the dynamics of such communities. However, detecting accurate community structures that evolve over time adds additional challenges. Almost all the state-of-the-art algorithms are designed based on seemingly the same principle while treating the problem as a coupled optimization model to simultaneously identify community structures and their evolution over time. Unlike all these studies, the current work aims to individually consider this three measures, i.e. intra-community score, inter-community score, and evolution of community over

     This study was aimed to investigate the effects of Cuminum cyminum seed aqueous extract on the function and histological structure of rat kidney treated with dibutyl phthalate (DBP). Eighteen albino rats weighing 190-240g and aged 10-12 weeks were used for this study which went on for 28 days. The rats were divided into three groups (each with six animals): 1^st  group: control rats were given food and tap water, 2^nd group was given DBP (420mg/Kg. B.W.)  with tap water and diet, 3^rd group were fed cumin plant orally at a daily dose of (200 mg/kg B.W.) and DBP (420mg/kg. B.W.) was given with drinking water and fed with diet daily. Kidney and liver function parameters were measured and hi

The nuclear structure of  ⁴⁰Ar, ¹¹²Cd, ¹³³Cs, ¹⁵¹Eu, ¹⁵⁴Sm, and ²²⁶Ra target nuclei used in nuclear battery technology was investigated. These nuclei are widely used for the radioisotope thermo-electric generator space studies and for betavoltaic battery microelectronic systems. For this purpose, some nuclear static properties were calculated. In particular, the single particle radial nuclear density distribution, the corresponding root mean square radii, neutron skin thicknesses, and binding energies were calculated within the framework of Hartree-Fock approximation with Skyrme interaction. The bremsstrahlung spectra produced by the absorption of beta particles throu

In this work, the dynamic behavior of discrete models is analyzed with Beverton- Holt function growth . All equilibria are found . The existence and local stability are investigated of all its equilibria.. The optimal harvest strategy is done for the system by using Pontryagin’s maximum principle to solve the optimality problem. Finally numerical simulations are used to solve the optimality problem and to enhance the results of mathematical analysis