Preferred Language
Articles
/
jkmc-908
Comparison between Reference Infliximab (Remicade) and its Biosimilar (Remsima) in Patients with Ankylosing Spondylitis: A Field-based Pharmacoeconomic Study
...Show More Authors

Background: Ankylosing spondylitis is a chronic inflammatory disease that mostly involves the spine and sacroiliac joints. It is associated with a decreased quality of life. Biological medicines such as infliximab and its biosimilar are the mainstay treatments for active ankylosing spondylitis.

Objective: The study objective was to conduct a pharmacoeconomic study comparing the cost-effectiveness of the reference infliximab with its biosimilar in ankylosing spondylitis patients visiting public hospitals.

Subjects and Method: This is a two-center pharmacoeconomic study performed at two large teaching governmental hospitals in Baghdad, Iraq, which supplied infliximab to outpatients with ankylosing spondylitis. The outcome data were obtained from patient’s medical records and face-to-face interviews with the patients from December 2021 through April 2022. The Independent T-Test was used to measure the differences in areas of utility, and quality of life, between the two infliximab groups.

Results: The study recruited 62 patients with ankylosing spondylitis who received infliximab (31 received Remicade, and 31 received Remsima) for at least 12 weeks at two public teaching hospitals. The mean age of the patients was 37.85 years and 83.9% were men. In general, both reference infliximab and its biosimilar were successful in increasing the quality of life. Their importation costs were different from 2019 to 2021. The incremental cost-effectiveness ratio of reference infliximab versus biosimilar was $ 40,909/quality-adjusted life year (QALY) according to 2019 pricing. In contrast, in 2021 reference infliximab (Remicade) was less expensive and yielded slightly better quality of life improvement than biosimilar (Remsima) making Remicade more cost-effective (dominant).

Conclusion: Remicade was slightly superior to Remsima in quality of life improvement. However, it was difficult to determine whether the reference or its biosimilar was more cost-effective in 2019 because the health officials did not specify a willingness to pay per quality-adjusted life year. Compared to Remsima, Remicade was more cost-effective in 2021 because it was less expensive and more effective in terms of quality of life improvement.

Scopus Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Thu Nov 30 2023
Journal Name
Iraqi Journal Of Science
Attention Mechanism Based on a Pre-trained Model for Improving Arabic Fake News Predictions
...Show More Authors

     Social media and news agencies are major sources for tracking news and events. With these sources' massive amounts of data, it is easy to spread false or misleading information. Given the great dangers of fake news to societies, previous studies have given great attention to detecting it and limiting its impact. As such, this work aims to use modern deep learning techniques to detect Arabic fake news. In the proposed system, the attention model is adapted with bidirectional long-short-term memory (Bi-LSTM) to identify the most informative words in the sentence. Then, a multi-layer perceptron (MLP) is applied to classify news articles as fake or real. The experiments are conducted on a newly launched Arabic dataset called the Ara

... Show More
View Publication Preview PDF
Scopus Crossref
Publication Date
Sat Dec 01 2012
Journal Name
Journal Of Engineering
Effect Of Technology Based Learning As A Supplement To Traditional Technology On Student's Achievement
...Show More Authors

This paper describes a practical study on the impact of learning's partners, Bluetooth Broadcasting system, interactive board, Real – time response system, notepad, free internet access, computer based examination, and interaction classroom, etc, had on undergraduate student performance, achievement and involving with lectures. The goal of this study is to test the hypothesis that the use of such learning techniques, tools, and strategies to improve student learning especially among the poorest performing students. Also, it gives some kind of practical comparison between the traditional way and interactive way of learning in terms of lectures time, number of tests, types of tests, student's scores, and student's involving with lectures

... Show More
View Publication Preview PDF
Crossref
Publication Date
Tue Aug 31 2021
Journal Name
Iraqi Journal Of Science
Development of a Job Applicants E-government System Based on Web Mining Classification Methods
...Show More Authors

     Governmental establishments are maintaining historical data for job applicants for future analysis of predication, improvement of benefits, profits, and development of organizations and institutions. In e-government, a decision can be made about job seekers after mining in their information that will lead to a beneficial insight. This paper proposes the development and implementation of an applicant's appropriate job prediction system to suit his or her skills using web content classification algorithms (Logit Boost, j48, PART, Hoeffding Tree, Naive Bayes). Furthermore, the results of the classification algorithms are compared based on data sets called "job classification data" sets. Experimental results indicate

... Show More
View Publication Preview PDF
Scopus (5)
Scopus Crossref
Publication Date
Tue Jun 01 2021
Journal Name
Baghdad Science Journal
A New Methodology to Find Private Key of RSA Based on Euler Totient Function
...Show More Authors

          The aim of this paper is to present a new methodology to find the private key of RSA. A new initial value which is generated from a new equation is selected to speed up the process. In fact, after this value is found, brute force attack is chosen to discover the private key. In addition, for a proposed equation, the multiplier of Euler totient function to find both of the public key and the private key is assigned as 1. Then, it implies that an equation that estimates a new initial value is suitable for the small multiplier. The experimental results show that if all prime factors of the modulus are assigned larger than 3 and the multiplier is 1, the distance between an initial value and the private key

... Show More
View Publication Preview PDF
Scopus (9)
Crossref (3)
Scopus Clarivate Crossref
Publication Date
Wed Nov 16 2016
Journal Name
Eurasip Journal On Wireless Communications And Networking
Evaluation of efficient vehicular ad hoc networks based on a maximum distance routing algorithm
...Show More Authors

Traffic management at road intersections is a complex requirement that has been an important topic of research and discussion. Solutions have been primarily focused on using vehicular ad hoc networks (VANETs). Key issues in VANETs are high mobility, restriction of road setup, frequent topology variations, failed network links, and timely communication of data, which make the routing of packets to a particular destination problematic. To address these issues, a new dependable routing algorithm is proposed, which utilizes a wireless communication system between vehicles in urban vehicular networks. This routing is position-based, known as the maximum distance on-demand routing algorithm (MDORA). It aims to find an optimal route on a hop-by-ho

... Show More
View Publication Preview PDF
Scopus (26)
Crossref (18)
Scopus Clarivate Crossref
Publication Date
Sun Apr 26 2020
Journal Name
Iraqi Journal Of Science
Fabrication of a Chemical Sensor Based on Surface Plasmon Resonance via Plastic Optical Fiber
...Show More Authors

In this work, a chemical optical fiber sensor based on Surface Plasmon Resonance (SPR) was designed and implemented using plastic optical fiber. The sensor is used for estimating refractive indices and concentrations of various chemical materials (methanol, distilled water, ethanol, kerosene) as well as for evaluating the performance parameters such as sensitivity, signal to noise ratio, resolution and the figure of merit of the fabricated sensor. It was found that the value of the sensitivity of the optical fiber-based SPR sensor, with 40 nm thick and 10 mm long Au metal film of exposed sensing region, was 3μm/RIU, while the SNR was 0.24, the figure of merit was 20, and the resolution was 0.00066. The sort of optical fiber utilized i

... Show More
View Publication Preview PDF
Scopus (17)
Crossref (11)
Scopus Crossref
Publication Date
Thu Dec 01 2016
Journal Name
Journal Of Engineering
A Hybrid Coefficient Decimation- Interpolation Based Reconfigurable Low Complexity Filter Bank for Cognitive Radio
...Show More Authors

Non uniform channelization is a crucial task in cognitive radio receivers for obtaining separate channels from the digitized wideband input signal at different intervals of time. The two main requirements in the channelizer are reconfigurability and low complexity. In this paper, a reconfigurable architecture based on a combination of Improved Coefficient Decimation Method (ICDM) and Coefficient Interpolation Method (CIM) is proposed. The proposed Hybrid Coefficient Decimation-Interpolation Method (HCDIM) based filter bank (FB) is able to realize the same number of channels realized using (ICDM) but with a maximum decimation factor divided by the interpolation factor (L), which leads to less deterioration in stop band at

... Show More
View Publication Preview PDF
Publication Date
Thu Feb 06 2025
Journal Name
Journal Of Baghdad College Of Dentistry
Fracture resistance of endodontically treated premolars with extensive MOD cavities restored with different composite restorations (An In vitro study)
...Show More Authors

Background: This in vitro study evaluated the fracture resistance of weakened endodontically treated premolars with class II MOD cavities restored with different composite restorations (Low-shrinkage Filtek P90, nanohybrid Filtek Z250 XT and SDR bulk fill). The type and mode of fracture were also assessed for all the experimental groups. Materials and Method: Fifty human adult maxillary premolar teeth were selected for this study. Standardized extensive class II MOD cavities with endodontic treatment were prepared for all teeth, except those that were saved as intact control. The teeth were divided into five groups of ten teeth each (n=10): (Group 1) intact control group, (Group 2) unrestored teeth with endodontic treatment, (Group 3) resto

... Show More
View Publication Preview PDF
Publication Date
Sun Jan 01 2023
Journal Name
Journal Of Molecular Liquids
Theoretical modeling study on preparation of nanosized drugs using supercritical-based processing: Determination of solubility of Chlorothiazide in supercritical carbon dioxide
...Show More Authors

View Publication
Scopus (11)
Crossref (11)
Scopus Clarivate Crossref
Publication Date
Thu May 13 2021
Journal Name
Al-kindy College Medical Journal
Vitamin D deficiency/ insufficiency and some of its related factors in a sample of Iraqi pregnant women and their neonates at Al-Elwiya Maternity Teaching Hospital during 2019
...Show More Authors

Background: Vitamin D deficiency/ insufficiency is common in different age groups in both genders especially among pregnant women and neonates where it is associated with several adverse outcomes including preeclampsia and preterm delivery.  

Objectives: To assess the extent of vitamin D deficiency/ insufficiency among mothers and their neonates and some factors related to it and identify some adverse outcomes of the deficiency/ insufficiency on neonates (preterm birth and low birth weight).

Subject and Methods: A cross-sectional study was conducted on 88 Iraqi pregnant women and neonates admitted to “Al-Elwiya teaching hospital for maternity” in Baghdad- Al

... Show More
View Publication Preview PDF
Crossref (1)
Crossref