Background: Dyslipidemia is a major cause of
cardiovascular disease, which in turn, is the most
common cause of female morbidity and mortality.
Postmenopausal women (natural and surgical) are at
higher risk of developing cardiovascular disease,
especially coronary artery atherosclerosis.
Objective: To observe the relationship between blood
lipids: total cholesterol (TC), high density lipoproteincholesterol (HDL-C), low density lipoproteincholesterol (LDL-C), triglycerides (TGs), and very low
density lipoprotein- cholesterol (VLDL-C), LDL-C/
HDL-C ratio (atherogenic index) and menopausal
status, and to determine the co-factors that may explain
this relationship
Methods: A prospective, cross-sectional study, which
includes 279 women, age range from 35-55 years
agreed to participate in this study. They were divided
into 4 groups according to their menopausal status.
These were pre-, peri post- natural and surgical postmenopausal. Data were collected from participants in a
pre-coded questionnaire and an overnight fasting blood
sample was collected for biochemical analysis.
Results: Postmenopausal women had higher levels of
lipids than pre or peri-menopausal. TC concentration
and LDL-cholesterol levels were higher in natural and
surgical menopause than in pre and pri-menopausal
women (p<0.01 and p<0.05 respectively). While
LDL/HDL-C ratio (atherogenic index) were higher in
the surgical postmenopausal women than in premenopausal group (p<0.05). No significant inter-group
differences were found in HDL-C. Triglycerides, and
VLDL levels were higher in surgical menopause group
than in both pre- and peri-menopause groups (p<0.05).
No significant differences were demonstrated in pre-,
peri-, and natural menopausal women with regard to
triglyceride and VLDL levels and LDL/HDL-C ratio.
Conclusion : Dyslipidemia is more frequent among
women with natural and surgical menopause groups
than in the other groups. This makes those women
more susceptible to CVD. Certain co factors appear to
have direct associations with lipid levels in each group
and those were discussed.
The research gained its importance from the importance of technical reserves in the insurance activity and its impact on the result of the activity of insurance companies and their financial position and thus reflected on the insurance prices as the technical reserves are one of the most important and most valuable budget items usually, as well as that the insurance activity has a role in maintaining economic development where some countries develop laws and instructions for the formation of those reserves binding application to insurance companies and the fact that the financial statements in general are of interest to shareholders, banks, the General Tax Authority and other beneficiaries In the insurance activity as policyholders and t
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The research concluded that
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