A Simple, rapid and sensitive extractive and spectrophotometric method has been described for the analysis of diphenhyldramine –HCl (DPH) in pure form and in pharmaceutical formulations. The method is based on the formation of chloroform soluble ion-pair complex with Bromophenol blue(BPB) in a phthalate buffer at pH 3.0.The extracted complex shows maximum absorbance at 410 nm. Beer's law is obeyed in the concentration range 0.2-25.0 µg.ml-1. The molar absorptivity and Sandell's sensitivity for the system being 2.416x104 L.mol-1.cm-1 and 0.012µg.cm-2, respectively. The limit of detection was found to be 0.155 µg.ml-1. The proposed method was successfully applied to the determination of the drug in pharmaceutical formulation and satisfactory results were obtained.
Univariate and Simplex Optimization for The Analysis of Diphenhydramine-HCl Through Ion-pair Formation
The Analysis of Diphenhydramine-HCl Through Ion-pair Formation
Univariate and Simplex Optimization
Publication Date
Thu Aug 01 2019
Journal Name
Journal Of Economics And Administrative Sciences
مقارنة مقدرات بيز لدالة المعولية لتوزيع باريتو من النوع الاول باستعمال دوال معلوماتية مضاعفة مختلفة
Pareto type I distribution
reliability function
bayes method
double prior distributions (chi-gamma square distribution. gamma- erlang distribution
erlang exponential distribution
the squared error loss function.
توزيع باريتو من النوع الاول
دالة المعولية
طريقة بيز
الدوال المعلوماتية المضاعفة : توزيع مربع كاي- كاما
توزيع كاما - ارلنك
التوزيع ارلنك- الاسي
دالة الخسارة التربيعية.
The comparison of double informative priors which are assumed for the reliability function of Pareto type I distribution. To estimate the reliability function of Pareto type I distribution by using Bayes estimation, will be used two different kind of information in the Bayes estimation; two different priors have been selected for the parameter of Pareto type I distribution . Assuming distribution of three double prior’s chi- gamma squared distribution, gamma - erlang distribution, and erlang- exponential distribution as double priors. The results of the derivaties of these estimators under the squared error loss function with two different double priors. Using the simulation technique, to compare the performance for
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