Cryptosporidium parvum
intestinal and spleen homogenate
IFN-g
TNF-a
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Cryptosporidiosis is mainly cause a persistent diarrhea in immune compromised patients, BALB/c mice have
been suppressed by dexamethasone, tissue Th1, Th2 and Th17 cytokines concentrations in the ileum were significantly diminished
in both infected and immunosuppressed mice. Level of IFN-g, TNF-a, IL-12, IL-6, IL-17A was increased in level, IL-4 didn’t
increases, in both ileal and spleen tissue. Levels of above cytokines were examined in spleen in order to follow the proliferation
of CD4+ T-cell during C. parvum infection.