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jih-1773
Determination of Integrinα2 (ITGA2), Progesterone, Prolactin, Estradiol, Zinc and Vitamin C in Serum of Female Iraqi Patients with Breast Cancer
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Back ground: Cancer is the second leading cause of death throughout the world. Breast cancer, is one of the leading mortality reasons in women from Western Countries, in Iraq, breast cancer is the second reason of death After cardiovascular Diseases.

Material and method:

The study was carried out of period from October/2016-january /2017 and  included (90) serum samples for Iraqi women suffered from breast cancer . Samples were divided into two groups ,the first group included (66) patients (females) their age rang (22-55) years which attended to (tumor unit) at medical city educational oncology hospital and Al-Amal Al-Waatanii hospital in Baghdad ,the second group included (38) for females apparently healthy their age (22-55) were studied as a control group. All patients women which included in this study were enrolled to a diagnostic criteria which made according to clinical, mamografical, histological finding. All of them were early diagnosed (without treatment).The disease was diagnosed by consultant medical staff at the hospital .Three (3ml) of peripheral blood has been drawn from both understudying groups, serum isolated and placed in Eppendorf tube in deep freeze (-20) until used. To determin the understudying  hormones (progesterone ,prolactin and estradiol ),Eliza technique has been used while  vitamin c and zinc were determined sepctrophotometricly.

Result:

 By ELISA technique (ITGA2) recorded a non-significant differences in patients. Progesterone recorded a significantly increasing in patients (P<0.01). Prolactin showed a higher significantly increasing in patients (p< 0.01), while estradiol serum level  recorded a higher significantly decreasing (P<0.01) in patients .The result of biochemistry study part which included zinc and vitamin C, zinc  recorded   a highest significantly decreasing (P<0.01) in patients,. As well as vitamin C recorded a significantly decreasing (P<0.05) in patients.

 

Conclusion:

 According to the significant correlation between the three studied factors (integrin, progesterone and vitamin c) we may conclude that increasing level of progesterone and decreasing level of vitamin c may effect integrin expression in a downregulation  manner and perhaps breast cancer occurring and prognosis

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Publication Date
Sun Apr 03 2016
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Imaging and clinicopathological characteristics of breast cancer among women under the age of 40 years
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Background: although breast cancer in young women is less common and often overlooked, it is still considered a major health concern.
Objectives: to evaluate the demographic, clinical, radiological and histopathological characteristics of breast cancer among a sample of Iraqi women diagnosed under the age of 40 years.
Patients and methods: a retrospective study enrolled 73 females below the age of 40 years with a history of breast cancer. All data was extracted from an established information system database designed by the Principal Investigator of the Iraqi National Breast Cancer Research Project under supervision of the International Agency for Research on Cancer (IARC) over a 4-years period from 2011 to 2014.
Results: sevent

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Publication Date
Sun Jul 03 2016
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Imaging and clinicopathological characteristics of breast cancer among women under the age of 40 years
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Background: although breast cancer in young women is less common and often overlooked, it is still considered a major health concern.
Objectives: to evaluate the demographic, clinical, radiological and histopathological characteristics of breast cancer among a sample of Iraqi women diagnosed under the age of 40 years.
Patients and methods: a retrospective study enrolled 73 females below the age of 40 years with a history of breast cancer. All data was extracted from an established information system database designed by the Principal Investigator of the Iraqi National Breast Cancer Research Project under supervision of the International Agency for Research on Cancer (IARC) over a 4-years period from 2011 to

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Publication Date
Sun Dec 02 2012
Journal Name
Baghdad Science Journal
The Relation of IGF-1 and Insulin Resistance in a Sample of Iraqi Obese Type 2 Diabetic Patients with Macrovascular Disease
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Type 2 diabetes mellitus(T2DM) is a metabolic disease that is associated with an increased risk for atherosclerosis by 2-4 folds than in non- diabetics. In general population, low IGF-1 has been associated with higher prevalence of cardiovascular disease and mortality .This study aims to find out the relationship between IGF-1 level and other biochemical markers such as Homeostasis Model Assessment insulin resistance(HOMAIR) and Body Mass Index(BMI) in type 2 diabetic patients . This study includes (82) patients (40 females and 42 males) with age range (40-75) years,(34) non obese diabetic patients and (48) obese diabetic patients. The non obese individuals considered

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Publication Date
Tue May 01 2018
Journal Name
Journal Of Information Engineering And Applications
Development of Prognosis Factors in a Scoring System for Predicting of Breast Cancer Mortality
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Today, the prediction system and survival rate became an important request. A previous paper constructed a scoring system to predict breast cancer mortality at 5 to 10 years by using age, personal history of breast cancer, grade, TNM stage and multicentricity as prognostic factors in Spain population. This paper highlights the improvement of survival prediction by using fuzzy logic, through upgrading the scoring system to make it more accurate and efficient in cases of unknown factors, age groups, and in the way of how to calculate the final score. By using Matlab as a simulator, the result shows a wide variation in the possibility of values for calculating the risk percentage instead of only 16. Additionally, the accuracy will be calculate

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Publication Date
Wed Nov 28 2018
Journal Name
Iraqi Journal Of Science
Evaluation of TLR-2 sera levels in a sample of Iraqi pulmonary TB patients
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The non-specific response of immunity has developed as the initial barrier for human protection from invading pathogens, which comprises certain pathogen recognition receptors (PRR) for instance toll-like receptors (TLRs). Toll like receptor 2 (TLR 2) is capable of recognizing pathogen associated molecular patterns (PAMP) coded by Mycobacterium tuberculosis. To evaluate TLR 2 level in sera of pulmonary tuberculosis (TB) patients. About 120 subjects, involving 80 patients with pulmonary TB including 40 multiple drug resistance (MDR), 20 recently diagnosed pulmonary TB (RD) and 20 recurrent TB patients named as old cases (OC), in addition to 40 apparently healthy individuals were studied as control group. Sera from 68 TB patients

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Publication Date
Sun Jun 02 2013
Journal Name
Baghdad Science Journal
Detection of Type 2 Diabetes Mellitus in Serum from Women with Polycystic Ovarian Syndrome
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Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorder. To determine the metabolic disorders in women with PCOS, (25) women with PCOS ages (15 - 47) years have been investigated and compared with (20) healthy individuals. All the studied groups were carried out to measure fasting blood sugar, (anti-GAD Ab, anti ?-islet cell Ab by IFAT) and measured insulin level by ELISA. There was significant elevation in the concentration of fasting blood sugar than in control groups (p ? 0.05) and there was negative results for anti-GAD Ab and anti ?-islet cell Ab by IFAT test for serum of women with PCOS, while there was significant differences in the insulin level for women with PCOS compared with control groups (p ? 0.05), these

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Publication Date
Tue Jan 01 2013
Journal Name
Baghdad Science Journal
Detection of Type 2 Diabetes Mellitus in Serum from Women with Polycystic Ovarian Syndrome
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Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorder. To determine the metabolic disorders in women with PCOS, (25) women with PCOS ages (15 - 47) years have been investigated and compared with (20) healthy individuals. All the studied groups were carried out to measure fasting blood sugar, (anti-GAD Ab, anti β-islet cell Ab by IFAT) and measured insulin level by ELISA. There was significant elevation in the concentration of fasting blood sugar than in control groups (p ≤ 0.05) and there was negative results for anti-GAD Ab and anti β-islet cell Ab by IFAT test for serum of women with PCOS, while there was significant differences in the insulin level for women with PCOS compared with control groups (p ≤ 0.05),

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Publication Date
Wed Jan 01 2020
Journal Name
Annals Of Tropical Medicine And Public Health
Role of high sensitivity C - Reactive protein and some of heavy metals in patients with rheumatoid arthritis
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Publication Date
Mon Oct 25 2021
Journal Name
Iraqi Journal Of Science
Determination of some virulence factors of Citrobacter freundii isolated from Iraqi patients
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      This study included the isolation and identification of Citrobacter freundii from 220 samples collected from inpatients and outpatients suffering from urinary tract infection (UTI) and identified at the laboratory of the General Samarra Hospital in Samarra City, Iraq. The study was conducted to investigate some of the virulence factors produced by C. freundii. The results showed that 67 isolates were  belonging to the C. freundii, with a rate of  30.45%. Twenty eight samples were from inpatients (41.8%)  and 39 samples were from outpatients. The bacterial identification was based on cultural and biochemical tests and confirmed by using VIT

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Publication Date
Tue Jun 30 2015
Journal Name
Al-kindy College Medical Journal
Surgical –Audit on breast cancer risk factors in AL-Russafa district in Baghdad
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Background: Breast cancer remains a substantial cause of morbidity and mortality, there is a need for continued efforts to understand the etiology of the disease, maintain screening effort, implement prevention strategies, and develop better treatments.Objective: To analyze the risk factors, improve early detection and prevention of breast cancer in Al-Russafa district- Baghdad, aiming to increase survival rate and improve the quality of life.Methods: A cross sectional audit of 258 breast cancer cases seen at Al-Elwiya maternity teaching hospital from January2009 to December 2011,data collected from patients files were: age, gender , residency, marital status, parity, age at menarche and menopause age at first live birth, hormonal therap

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