Preferred Language
Articles
/
jih-1660
A New Biological System For Detecting Environmetal Carcinogens And /Or Mutagenes And Their Adversary
...Show More Authors

A  new  test  system  for  detecting  environment  carcinogenes and/or  mutagenes  and  their  adversary  It  has  been  induced.  One hundred and fifty   mutants   were isolated from   the basidiomycete fungus Coprinus cinereus   which were   resistant to guanine analogue S- az.aguanine .All the spontaneous and induced with UV light origin mutants were isolated from the wild type strains Bc9/6.6 and  Hd5.5

.These mutants were te ted on selective medium containing  different

concentrations of the analogue and also to their ability to usc purine bases and their degredated  products as  a sole  nitrogene source were tested ; and their ability to grow on HAT   medium was tested . According  to  the results obtained  from these test;  mutants  were

classified into four phenotypic groups for each  iJd -type strain .

All  the  8-az.aguanine  resistant  mutants  were  d.ikaryotized   with

compatible wild strains. The dikaryons produced were unable to grow on  medium           containing        8-az.aguanine                     which               establish the recessiveness of the mutations to their respective wi ld-type alleles. Complementation   test  detcrmind  four  genes   which  controll   the resi stance  to 8- azaguaninc in Coprinus cincres   .These genes were desi gnated  azg-1, azg-2, azg'-3, azg-4.Three of these genes azg-1, azg-2 and azg'-4werc carried by Bc9/6.6 and Hl /5.5 mutants. While, azg-3 gene  was found in Bc9/6.6 mutants only.

These  genes  are determ.ind for  the  first  time  in  fungus coprinus cinereus  .

Mutants which carry azg-1  gene were characterized by their inability to use   hypozanthine and                                              guanine as a sole nitrogen source in the

medium ; their failure to grow  on HAT medium  and their resistance

to all concentrations of 8- az.aguanine used.This gene is considered to

 

 

 

 

IBN AL- HAITHAM J.FOH PURE & API'L.SCI.         VOL.19(4) 2006

 

represent  a mutation led to   lose or   modify the specificity of the enzyme hypoxauthine -guanine phosphoribosyl transferase (HGPRT) whi ch play an important role in transferring hypoxauthine and guanine to their nucleotides  by salvage pathway.

Spore analysis indi cated that azg'-1  gene locted in linkage group II

,since it gave a distance of 28 map units with the mating type gene

B.

The assessment of the cytotoxic , mutagn ic and antimutagc•tic role of

the  aqueous extract of  garl ic     (Allium  sativum  L.)  against the genotoxic effect of mitomycin - C

( MMC ) evaluate the ability of the mutagen to induce mutation in

HGPRT gene by    using the asexual spores (oidia )of Copninus cineraus for the strain AZG78 and by depending on the viabil ity and mutation rate in HGPRT gene test .To assess cytotoxity and mutagenecity of garlic extract , gradual concentrations were prepared . The concentration of choice was considered with respect to  two factors ; high survi val rate and low mutagenic  activity (similar to negative control ). To examine the antimutagenic  effects of  the extract, an interation was made between the crude  extract and the mutagen   MMC with respect to three kinds of treatments before , aOer and with mutagen . The study concentrated on two sides 1- on the toxic and /or m utagenic effect of the aqueous extract of garlic . 2 - Antimutagenic activity of the extract with respect to   the mutageen MMC . However,   this activity was dependent on the type of the treatment . The extract showed best antimutagenic activity when it was used before the mutagen , so itis considered as desmutagen to the genotox i c effects of MMC.

These data support the hypothesis that garlic compounds may be eflicacius in preventions of cancer and also we could use the HGPRT

gene as  a  sensitive biological  system  in  detecting environmental mutagenes or carcinogens and their adversary .

View Publication Preview PDF
Quick Preview PDF
Publication Date
Sun Jan 01 2023
Journal Name
The Egyptian Journal Of Hospital Medicine
Changes in Interleukin-35 (IL-35), Anti-TSHR antibody and Human Insulin- like Growth Factor 1 Receptor (IGF1R) in Graves’ Disease Patients Treatedwith Radioactive Iodine
...Show More Authors

View Publication
Crossref
Publication Date
Mon Dec 05 2022
Journal Name
Baghdad Science Journal
Effects of Castor Oil Nanoemulsion Extracted by Hexane on the Fourth Larval stage of Culex quinquefsciatus from Al Hawizeh Marsh/Iraq, and Non- Targeted Organism
...Show More Authors

           The current study aims to show the importance of plant products as mosquitocides against Culex quinquefasciatus. Castor oil Nanoemulsions were subedit in various ratios including castor oil, ethanol, tween 80, and deionized water by using ultrasonication. Thermodynamic, centrifugation, PH, assay which improved that the formula  of 10 ml  of castor  oil, ethanol  5ml, tween 80 (14 ml) and deionized water 71ml was more stable than other formulas. The stable formula of castor oil nanoemulsion was characterized by transmission electron microscopy (TEM) and dynamic light scattering (DLS). Nanoemulsion droplets were spherical in shape and were found to have a Z-average diameter of 87.4nm. A concentration of ca

... Show More
View Publication Preview PDF
Scopus (3)
Crossref (1)
Scopus Crossref
Publication Date
Sat Dec 30 2017
Journal Name
Iraqi National Journal Of Nursing Specialties
Assessment of Levels of premenstrual psychological and physical Problems (Premenstrual Syndrome-PMS) of Students of the Colleges of Bab Al-Mua’dham Complex/ University of Baghdad
...Show More Authors

Objectives: To assess levels of premenstrual psychological disorders of the students in Bab Al-Mua’dham Complex and to find out the relationship between the levels of premenstrual psychological and physical disorders and some demographic characteristics of the students. Methodology: A descriptive study was accomplished throughout the period from the 1st of October, 2015 to the 8th of July, 2016 to assess the psychological and physical problems. A purposive sample of 313 students distributed among different colleges of Bab Al-Mua’dam complex distributed as following: 82 students are from college of Arts; 79 students are from College of Languages; 48 students are from college of Islamic Sciences: and 104 are from College of Nursing. For t

... Show More
View Publication Preview PDF
Crossref
Publication Date
Sat Sep 01 2012
Journal Name
Australian Journal Of Basic And Applied Sciences
Electrochemical interferences of Mn<sup>2+</sup> with Hg<sup>2+</sup>, Cd<sup>2+</sup> and Cu<sup>2+</sup> at different modified GCE
...Show More Authors

Glassy carbon electrode (GCE) was modified with carbon nanotubes CNT and C60 by attachment and solution evaporation techniques, respectively. CNT/Li+/GCE and C60/Li+/GCE were prepared by modifying CNT/GCE and C60/GCE in Li+ solution via cyclic voltammetry (CV) potential cycling. The sensing characteristics of the modified film electrodes, demonstrated in this study for interference of Mn2+ in different heavy metals ion esp. Hg2+, Cd2+ and Cu2+. The interfering effect was investigated that exert positive interference on the redox peaks of Mn2+. The modification of GCE with nano materials and Li+ act an enhancement for the redox current peaks to observe the effect of interference for Mn2+ in 1:1 ratio with different heavy metals ion.

Scopus (3)
Scopus
Publication Date
Tue Jul 15 2025
Journal Name
Modern Sport
Job commitment and its relation to the behavior of citizenship in physical education teachers Directorate of Education Baghdad AL- Karkh THird Search submitted by Research
...Show More Authors

View Publication Preview PDF
Publication Date
Fri Jan 01 2016
Journal Name
Journal University Of Kerbala
Synthesis and Characterization of Some Metal Complexes of [2-chloro-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylcarbamothioyl)acetamide] (L)
...Show More Authors

A new ligand [ 2-chloro-N- (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro -1H-pyrazol- 4-ylcarbamothioyl)acetamide](L) was synthesized by reacting the Chloro acetyl isothiocyanate with 4-aminoantipyrine,The ligand was characterized by(C HNS) elemental microanalysis and the spectral measurements including Uv-Vis ,IR ,1H and13C NMR spectra, some transition metals complex of this ligand were prepared and characterized by Uv-Vis, FT-IR spectra, conductivity measurements, magnetic susceptibility and atomic absorption. From the obtained results the molecular formula of all prepared complexes were [M(L)2(H2O)2]Cl2 (M+2 =Mn, Co, Ni, Cu, Zn, Cd and Hg),the proposed geometrical structure for all complexes were octahedral.

Publication Date
Wed May 12 2021
Journal Name
Annals Of The Romanian Society For Cell Biology
Contribution Ratio of Cognitive Learning Outcome in the Performance of the Two Skills of Mastering by Parallel Spherical Standing and Equilibrium on the Balance Beam
...Show More Authors

The purpose of this paper is to identify the statistical indicators of the searched variables and identify the relationship between the cognitive learning outcome and the performance of the two mastering skills by parallel spherical standing and equilibrium on the balance beam. And the identification of the percentage of the cognitive learning outcome contribution to the performance of the two mastering skills by parallel spherical standing and the equilibrium on the balance beam. The two researchers used the descriptive approach in the survey method and the correlational relations, being the most appropriate to the nature of the research problem. The research community for the second stage students in the College of Physical Education and

... Show More
View Publication Preview PDF
Publication Date
Thu Oct 01 2020
Journal Name
Biochemical And Cellular Archives
Study on the effect of methotraxate drug on Retinol-Binding Protein 4 (RBP4), nesfatin and some trace elements in Iraqi male patients with rheumatoid arthritis
...Show More Authors

Methotrexate (MTX) is one of the most effective medications to treat rheumatoid arthritis (RA).Aserum of 60 Iraqi male patients suffering from RA as (G1) was newly diagnosis and the same patient in G1 after taking MTX as G2 and 40 Iraqi male healthy control as G3. Nesfatin-1 (Nf-1) is belong to the adipokine family withpleiotropic effect. Nf-1 has been found in different tissues, including stomach, pancreas, bone cells, cartilage and heart. Retinol binding protein (RBP4) was known as transpoter of retinol from its storage sites in the liver to the extrahepatic tissues. Moreover, RBP4 acts as adipokine and contributes in the pathophsyology of prototypic inflammatory disease, rheumatoid arthritis (RA). The results showed a significant increas

... Show More
Scopus
Publication Date
Mon Jul 04 2022
Journal Name
Journal Of Accounting And Financial Studies ( Jafs )
The role of agricultural insurance in the prevention of financing risks in the form of slam : "An Empirical Study on Shikan Insurance and Reinsurance Company
...Show More Authors

The aim of this research is to introduce agricultural insurance, to define financing in the form of salam and the role of agricultural insurance in the prevention of risks to agricultural finance operations in the form of salam by verifying the hypotheses through which to reach the results, including the imposition of risks for agricultural finance in the form of salam, The study of agricultural finance in the form of salm, the deductive approach to the development of the problem of research and hypotheses, and the inductive method to extrapolate the results through analysis and brother The researcher concluded that agricultural insurance works to bridge the risks facing agricultural finance in the form of the ladder in cases of

... Show More
View Publication Preview PDF
Publication Date
Thu Dec 28 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Synthesis and Spectro-Kinetic Study of the Complexes of Pd+2 Ion with 2-(5-Bromo-2- pyridylazo)5diethylaminophenol Reagent in Ethanol – Water Solutions
...Show More Authors

      The complexes of Pd+2 ion with 2-(5-bromo-2-pyridylazo)-5-dieıhyl aminophenol (BPADAP) were studied kinetically and spectrophotometrically in aqueous ethanolic solutions. The reagent forms 1:1, 2:1 square planer and 1:1 bridged shape binuclear complexes with Pd+2 ion. All these complexes (violet colour) absorb light in the same region at 540, 575 and 618nm. The band at 618 nm seems to be specific for complexes of Pd+2ion with BPADAP.   The rate constants of the growth in 93% H2O + 7% ethanol of 1:1 and 2:1 complexes at 575 and 618 nm were followed the first order kinetics and are quite of the same values , 0.495 and 0.463 min- 1  respectively. The rate constants of the decay of 2:1 complex

... Show More
View Publication Preview PDF
Crossref