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In study of effective bioactive compounds, we have synthesized the Co((ІІ), Mn(ІІ), Fe(ІІ), Cu(ІІ), Ni(ІІ), and Zn(ІІ)
complexes of the Schiff base derived from trimethoprim and2'-amino-4-chlorobenzophenone and characterized by
spectroscopic (NMR, IR, Mass, UV–vis,), analytical, TGA studies and magnetic data .The solution electronic spectral study
suggests the stoichiometry of the synthesized complexes and Elemental analysis detected the square planer and octahedral
geometry of the compounds. The prepared metal complexes presented promoted efficiency versus the screened bacterial
(Escherichia Coli and Staphylococcus aureus) antibacterial efficacy against (Staphylococcus aureus, Salmonella spp., E. coli,
Vibrio spp., Pseud
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